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The map label for this gene is efp

Identifier: 50085316

GI number: 50085316

Start: 2176269

End: 2176847

Strand: Reverse

Name: efp

Synonym: ACIAD2206

Alternate gene names: 50085316

Gene position: 2176847-2176269 (Counterclockwise)

Preceding gene: 50085320

Following gene: 50085315

Centisome position: 60.49

GC content: 40.93

Gene sequence:

>579_bases
GTGCCAGTCATGGCCAGTTATTCTACAAATGAATTCAAGCAAGGCCTTAAGGTCATGCTTGACGGTAACCCATGTTCAAT
CATGGAAAATGAATATGTTAAGCCTGGTAAGGGTCAAGCATTCAACCGTGTAAAACTTCGTAACCTTAAAACAGGTAAAG
TTTTAGAAAAAACATTTAAATCTGGTGATTCACTAGAAGCAGCTGACATTGTAGAAGTAGAAATGGACTACCTTTACAAC
GATGGCGAGCTTTGGAACTTTATGGATCCTGTAACTTTTGAGCAAATTGCTGCAGATAAAGTTGCCATGGGTGATGCCGC
AAAATGGTTGAAAGATGACTCAAACGAAAAATGTAGCATTATGCTGTTTAATGGTGTGCCATTAAATGTAAGTGCCCCAA
ATTTTGTGGTCTTGAAAATTGTTGAAACTGATCCAGGTGTTCGTGGAGATACTTCTGGCGGTGGCGGCAAGCCTGCAAAA
CTTGAAACAGGTGCGGTTGTTCGTGTTCCGTTATTTGTTCAGCAAGAAGATAGCGTTCGCGTAGACACTCGTACGGGTGA
ATATTTAGAACGTGCATAA

Upstream 100 bases:

>100_bases
CGATTGCCAGTTTTGCTCTTGATATAAATAGTTTATCATGCGACACGGAAAAAATAATGCTAGTCTAGCATTAATACATT
TAAGTTAGTAAGTTTGGAGT

Downstream 100 bases:

>100_bases
TAGCCAAATAATAGACTATTATGGAAGGGTGATAAATAATCACCCTTTTTTTATGCCAAAGTCGTAGAGGAATATAACAA
AATAAGGAGTAAAGTCACTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFKSGDSLEAADIVEVEMDYLYN
DGELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSIMLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAK
LETGAVVRVPLFVQQEDSVRVDTRTGEYLERA

Sequences:

>Translated_192_residues
MPVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFKSGDSLEAADIVEVEMDYLYN
DGELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSIMLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAK
LETGAVVRVPLFVQQEDSVRVDTRTGEYLERA
>Mature_191_residues
PVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFKSGDSLEAADIVEVEMDYLYND
GELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSIMLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAKL
ETGAVVRVPLFVQQEDSVRVDTRTGEYLERA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=60.1063829787234, Blast_Score=242, Evalue=1e-65,
Organism=Escherichia coli, GI87082061, Length=185, Percent_Identity=25.9459459459459, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ACIAD (Q6FAA9)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046826.1
- ProteinModelPortal:   Q6FAA9
- SMR:   Q6FAA9
- STRING:   Q6FAA9
- GeneID:   2878440
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2206
- NMPDR:   fig|62977.3.peg.1597
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   WKVLEFL
- PhylomeDB:   Q6FAA9
- ProtClustDB:   PRK00529
- BioCyc:   ASP62977:ACIAD2206-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21121; Mature: 20990

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFK
CCEECCCCHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHC
SGDSLEAADIVEVEMDYLYNDGELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSI
CCCCCCCCEEEEEEEEEEECCCCEECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEE
MLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAKLETGAVVRVPLFVQQEDSVR
EEECCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCCEE
VDTRTGEYLERA
EECCCCHHHHCC
>Mature Secondary Structure 
PVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFK
CEECCCCHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHC
SGDSLEAADIVEVEMDYLYNDGELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSI
CCCCCCCCEEEEEEEEEEECCCCEECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEE
MLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAKLETGAVVRVPLFVQQEDSVR
EEECCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCCEE
VDTRTGEYLERA
EECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA