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The map label for this gene is aroC

Identifier: 50085163

GI number: 50085163

Start: 2018141

End: 2019232

Strand: Reverse

Name: aroC

Synonym: ACIAD2028

Alternate gene names: 50085163

Gene position: 2019232-2018141 (Counterclockwise)

Preceding gene: 50085164

Following gene: 50085156

Centisome position: 56.11

GC content: 44.87

Gene sequence:

>1092_bases
ATGGCAGGGAATAGTATAGGACAACTCTTTCGTGTCACAACGTGTGGCGAATCACATGGTGTGGGCTTGATGGCGATTGT
CGATGGCGTTCCACCTGGGCTTGAATTGTGTGAAGAAGATTTACAAAAAGATTTGGATCGACGTAAGCCTGGTACATCTA
AGTTTGCAACGCAGCGTAAAGAACCTGATCAAGTAAAAATAATTTCGGGCGTGTTTGAAGGTAAGACGACAGGCACATCG
ATTGGTTTGTATATTGAAAATACAGATCAGAAGTCTAAAGATTACGGCAATATCGCGCAAACTTTCCGTCCTGGTCATGC
CGATTATACTTATACGCAAAAGTATGGTTTCCGTGATTATCGAGGTGGTGGTCGTTCGAGTGCACGTGAAACGGCAATGC
GTGTTGCAGCAGGGGCTATTGCTAAAAAATATTTGGCAGAAAAGTTTGGCCTTGTGGTTCGTGGCCATGTCATACAGATT
GGCAATGAAGTCGCAGAAAAATTAGACTGGAATGAAGTTTCCCAGAATCCATTTTTCTGTGGCGATGTCGATGCTGTGCC
TCGCTTTGAGGCTTTGGTGACCTCTTTACGCGAGCAGGGAACAAGCTGTGGTGCCAAACTCGAAATTTTGGCCGAGCAAG
TTCCTGTGGGTTGGGGGGAGCCTGTTTTTGATCGTCTGGATGCAGATATTGCACATGCAATGATGAGCATTAATGCAGTT
AAAGGTGTTGAAATAGGGGATGGTTTTGCCGTAGCAGGACAATTTGGACATGAAACACGTGACGAATTAAGCACACAAGG
TTTTTTGGCGAATCATGCTGGTGGAATTTTAGGTGGAATTTCGAGTGGTCAAACCATTCGTGTTGCGATTGCACTTAAAC
CTACTGCAAGTATTACCACATCAGGAAAGACCATTAATTTGGATCGGGAAGATACAGATGTACTGACCAAAGGTCGCCAT
GATCCTTGTGTTGGCGTGCGCGCGACACCAATTGCAGAAGCAATGCTCGCCATTGTACTGATGGATCATTTTTTACGACA
TCGTGCTCAAAATGCGGATGTTGTTATGCCATTTGAACCCATAGCACCTTAA

Upstream 100 bases:

>100_bases
CCAGAAAGGTGGTTCAGGTATTTTTGCGTTAACGGCTGAGCAATGTCGTCGTTATCAACGTTTGTTTCAAGAATCTTTAG
ACGTATAAGGAGTTGTATAC

Downstream 100 bases:

>100_bases
GCATTTTGCTTTACAATTAACTGCCTCACGCCATGAATGACGTGAGGCATTTTTTATGACTTGTTATACACGTCGATAAA
GTTTTTATATGCGCTTGATT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLELCEEDLQKDLDRRKPGTSKFATQRKEPDQVKIISGVFEGKTTGTS
IGLYIENTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGLVVRGHVIQI
GNEVAEKLDWNEVSQNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEQVPVGWGEPVFDRLDADIAHAMMSINAV
KGVEIGDGFAVAGQFGHETRDELSTQGFLANHAGGILGGISSGQTIRVAIALKPTASITTSGKTINLDREDTDVLTKGRH
DPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVMPFEPIAP

Sequences:

>Translated_363_residues
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLELCEEDLQKDLDRRKPGTSKFATQRKEPDQVKIISGVFEGKTTGTS
IGLYIENTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGLVVRGHVIQI
GNEVAEKLDWNEVSQNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEQVPVGWGEPVFDRLDADIAHAMMSINAV
KGVEIGDGFAVAGQFGHETRDELSTQGFLANHAGGILGGISSGQTIRVAIALKPTASITTSGKTINLDREDTDVLTKGRH
DPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVMPFEPIAP
>Mature_362_residues
AGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLELCEEDLQKDLDRRKPGTSKFATQRKEPDQVKIISGVFEGKTTGTSI
GLYIENTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGLVVRGHVIQIG
NEVAEKLDWNEVSQNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEQVPVGWGEPVFDRLDADIAHAMMSINAVK
GVEIGDGFAVAGQFGHETRDELSTQGFLANHAGGILGGISSGQTIRVAIALKPTASITTSGKTINLDREDTDVLTKGRHD
PCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVMPFEPIAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=354, Percent_Identity=70.0564971751412, Blast_Score=490, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6321290, Length=376, Percent_Identity=42.5531914893617, Blast_Score=268, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_ACIAD (Q6FAR2)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046673.1
- ProteinModelPortal:   Q6FAR2
- SMR:   Q6FAR2
- STRING:   Q6FAR2
- GeneID:   2878788
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2028
- NMPDR:   fig|62977.3.peg.1935
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q6FAR2
- ProtClustDB:   PRK05382
- BioCyc:   ASP62977:ACIAD2028-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39092; Mature: 38961

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLELCEEDLQKDLDRRKPGTSKFATQRK
CCCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCC
EPDQVKIISGVFEGKTTGTSIGLYIENTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDY
CCCCEEEEEHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGLVVRGHVIQIGNEVAEKLDWNEVSQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHEEHHHHHHHHCCCHHCCCCCCEE
GDVDAVPRFEALVTSLREQGTSCGAKLEILAEQVPVGWGEPVFDRLDADIAHAMMSINAV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVAGQFGHETRDELSTQGFLANHAGGILGGISSGQTIRVAIALKPTASITT
CCEECCCCEEEECCCCCCHHHHHHHCCCHHHCCCCCEECCCCCCEEEEEEEECCCCEEEE
SGKTINLDREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVMPFEP
CCCEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
IAP
CCC
>Mature Secondary Structure 
AGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLELCEEDLQKDLDRRKPGTSKFATQRK
CCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCC
EPDQVKIISGVFEGKTTGTSIGLYIENTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDY
CCCCEEEEEHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGLVVRGHVIQIGNEVAEKLDWNEVSQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHEEHHHHHHHHCCCHHCCCCCCEE
GDVDAVPRFEALVTSLREQGTSCGAKLEILAEQVPVGWGEPVFDRLDADIAHAMMSINAV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVAGQFGHETRDELSTQGFLANHAGGILGGISSGQTIRVAIALKPTASITT
CCEECCCCEEEECCCCCCHHHHHHHCCCHHHCCCCCEECCCCCCEEEEEEEECCCCEEEE
SGKTINLDREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVMPFEP
CCCEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
IAP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA