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The map label for this gene is 50085149

Identifier: 50085149

GI number: 50085149

Start: 2005012

End: 2006724

Strand: Reverse

Name: 50085149

Synonym: ACIAD2014

Alternate gene names: NA

Gene position: 2006724-2005012 (Counterclockwise)

Preceding gene: 50085152

Following gene: 50085148

Centisome position: 55.76

GC content: 39.4

Gene sequence:

>1713_bases
ATGAAGCAAGAAACTGCACTGAAGTTGCTAAAAGCGGGTGAAAATGTTTTTTTAACTGGTTCGGCTGGTGCAGGAAAAAC
CTATACACTGAATCAGTACATCAACTATTTGAAAGTACGAAAAGTACCTGTGGCAGTTACAGCATCAACAGGAATTGCAG
CGACACATATGAATGGGATGACCATTCATACTTGGGCAGGCATTGGTATTAAAGATCGCTTGTCGGATGATGATCTTAAA
CGCATGAAAGAGCGAAAATATTTAAAAGAACATCTTGAAAATGCTCAGGTTTTAATTATTGATGAAATTTCGATGCTGCA
CGCCAAACAGCTTAATCTAGTGAACCAAGTACTCAAATATTTTAAAGAAAGTGATGAGGCTTTTGGTGGTATTCAGGTGA
TTGTTGCAGGCGATTTTTTTCAGTTGCCGCCTGTAGGAAAAAATGACGAACGCAATCGCGACAAGTTTTGTTTTATGTCC
GATGCCTGGGTCGAAGCTAAATTTCGGGTCTGCTATCTGACTGAACAGCATCGTCAGGACGATGAAATACTTAATCAAAT
TTTGAATGCGATTCGTGCACAGAATATTCAAAATGAGCATAAGCATGCTTTGCTTACATCACGGCAGCATAATATTGGCG
AAACTTTTACGCGTTTATACACGCACAATATGGATGTTGATAACATTAATTTTCAGCATTTGAATGAAATTGAAAATGAA
AGTCATCAATTTAATGCGGTTTTGGATGGTAACGACAAGCTTCTAGAAACTTTAAAGTCATCGGTACGTGCGCCTGAAGA
GCTGACTTTAAAAAAACATGCCAAAGTAATGTTTGTAAAAAACAATTTTGATATGGGCTATATCAACGGTAGTTTAGGTG
AAGTGATTGGGTTTGAAGAAGATGATGAACATGGCATTTTACCTAAAGTAAAAATGACTGACGGCACAACACTGTTGGTT
GAGCCTGAAACTTGGTCGATTGAAAATGAAGCAGGAAAGAGTATTGCCAGCTTTCAGCAAATTCCCCTGCGTTTAGCATG
GGCAATTACCATTCATAAAAGTCAGGGCATGACTTTAGAAGCTGCGGAAATTAATCTGACACATACTTTTGAAAAAGGTC
AGGGTTACGTGGCTTTATCCCGACTTAAATCTTTAACTGGCCTACGCTTACTTGGTTTTAATGAACAAGCTTTGGAGCTT
GATGCGCTGGCGCTTAAAGCGGACAAACGTTTTCAGGAATTATCACAAGAGGCAGAGGATCATTTTGCAGAAATTGATTT
GGCAGATCAGCACAAAGCCTTTATTCGCCACTGCGGTGGTACGCTCAATGAAACTGAAATTTCACGTAATGAGAAAAAGT
TGTTAAAAGGTGCGAAACAAAATTACGGATCAGCAACTTTAGATGAAACCCGTGCTTTGTTTGAAGAAGGTTATGAAATT
CAGGATATTGCTGTTGAGCGTGGTTTGACTCCAGCTACAATTATCAATCATTTGGCACGTTTGCAAAAAGAGCAAGGTCT
GGATATTTCTGTTGCTCACCCTGGCGAAGAGGTCGTCGAACAAATTCGTAAACTCTATAAGCGCGTACAAAAAAGCAAAC
GACCAGAAAACTTTAATGATGATGGTTCGATCAAACTCAAACCGATTGTTGAATTAACCAGTCCACGCATGGGCTATGAT
CAGGTGCGTCTAGCGCTGTTGTTTATTGAATAG

Upstream 100 bases:

>100_bases
ATTGAATTTAAATAATAAAAAACCAATTTTTATGTATTGGGATTTAACTTTCTCATTAAAATCGTTAAGCTATGCGCACA
TTTATTAAAGTCATTAGGTT

Downstream 100 bases:

>100_bases
TAGGGTCACCCGTATGCCACACGTTGTCATTGATTATTCTGCAAATTTAGAAAATTTTGAGCCTAAGCAACTTTTATTAA
AAATTAACCATGCATTGGTA

Product: helicase

Products: NA

Alternate protein names: Helicase; TPR Domain Protein; TPR Domain-Containing Protein; ATPase; Exonuclease V Subunit Alpha; Helicase-Related Protein; 5-3' DNA Helicase; Aaa ATPase; Glycosysltransferase; Hrdc Domain Protein; HRDC Domain Protein; Helicase-Family Protein; RecD-Like Exodeoxyribonuclease V Alpha Chain; RRM3/PIF1 Helicase-Like Protein; Helicase Protein; ATP-Dependent ExoDNAse Alpha Subunit; DNA Helicase AAA ATPase; DNA Helicase/AAA ATPase; Helicase RecD/TraA Family

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYINYLKVRKVPVAVTASTGIAATHMNGMTIHTWAGIGIKDRLSDDDLK
RMKERKYLKEHLENAQVLIIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGKNDERNRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQNIQNEHKHALLTSRQHNIGETFTRLYTHNMDVDNINFQHLNEIENE
SHQFNAVLDGNDKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDEHGILPKVKMTDGTTLLV
EPETWSIENEAGKSIASFQQIPLRLAWAITIHKSQGMTLEAAEINLTHTFEKGQGYVALSRLKSLTGLRLLGFNEQALEL
DALALKADKRFQELSQEAEDHFAEIDLADQHKAFIRHCGGTLNETEISRNEKKLLKGAKQNYGSATLDETRALFEEGYEI
QDIAVERGLTPATIINHLARLQKEQGLDISVAHPGEEVVEQIRKLYKRVQKSKRPENFNDDGSIKLKPIVELTSPRMGYD
QVRLALLFIE

Sequences:

>Translated_570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYINYLKVRKVPVAVTASTGIAATHMNGMTIHTWAGIGIKDRLSDDDLK
RMKERKYLKEHLENAQVLIIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGKNDERNRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQNIQNEHKHALLTSRQHNIGETFTRLYTHNMDVDNINFQHLNEIENE
SHQFNAVLDGNDKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDEHGILPKVKMTDGTTLLV
EPETWSIENEAGKSIASFQQIPLRLAWAITIHKSQGMTLEAAEINLTHTFEKGQGYVALSRLKSLTGLRLLGFNEQALEL
DALALKADKRFQELSQEAEDHFAEIDLADQHKAFIRHCGGTLNETEISRNEKKLLKGAKQNYGSATLDETRALFEEGYEI
QDIAVERGLTPATIINHLARLQKEQGLDISVAHPGEEVVEQIRKLYKRVQKSKRPENFNDDGSIKLKPIVELTSPRMGYD
QVRLALLFIE
>Mature_570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYINYLKVRKVPVAVTASTGIAATHMNGMTIHTWAGIGIKDRLSDDDLK
RMKERKYLKEHLENAQVLIIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGKNDERNRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQNIQNEHKHALLTSRQHNIGETFTRLYTHNMDVDNINFQHLNEIENE
SHQFNAVLDGNDKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDEHGILPKVKMTDGTTLLV
EPETWSIENEAGKSIASFQQIPLRLAWAITIHKSQGMTLEAAEINLTHTFEKGQGYVALSRLKSLTGLRLLGFNEQALEL
DALALKADKRFQELSQEAEDHFAEIDLADQHKAFIRHCGGTLNETEISRNEKKLLKGAKQNYGSATLDETRALFEEGYEI
QDIAVERGLTPATIINHLARLQKEQGLDISVAHPGEEVVEQIRKLYKRVQKSKRPENFNDDGSIKLKPIVELTSPRMGYD
QVRLALLFIE

Specific function: Unknown

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI82546872, Length=426, Percent_Identity=37.793427230047, Blast_Score=285, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI25143421, Length=420, Percent_Identity=33.0952380952381, Blast_Score=225, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17534623, Length=427, Percent_Identity=27.4004683840749, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537113, Length=427, Percent_Identity=27.4004683840749, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17533663, Length=427, Percent_Identity=27.1662763466042, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536913, Length=427, Percent_Identity=27.1662763466042, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17537851, Length=427, Percent_Identity=27.1662763466042, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17566502, Length=130, Percent_Identity=35.3846153846154, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321820, Length=309, Percent_Identity=38.1877022653722, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6323579, Length=333, Percent_Identity=38.7387387387387, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI19920652, Length=421, Percent_Identity=36.104513064133, Blast_Score=247, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64577; Mature: 64577

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYINYLKVRKVPVAVTASTGIAATHMNGM
CCHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCEEEEEECCCEEEEECCCE
TIHTWAGIGIKDRLSDDDLKRMKERKYLKEHLENAQVLIIDEISMLHAKQLNLVNQVLKY
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
FKESDEAFGGIQVIVAGDFFQLPPVGKNDERNRDKFCFMSDAWVEAKFRVCYLTEQHRQD
HHHCCCCCCCEEEEEECCEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEHHCCCH
DEILNQILNAIRAQNIQNEHKHALLTSRQHNIGETFTRLYTHNMDVDNINFQHLNEIENE
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
SHQFNAVLDGNDKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEE
CCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCC
DDEHGILPKVKMTDGTTLLVEPETWSIENEAGKSIASFQQIPLRLAWAITIHKSQGMTLE
CCCCCCCCEEEECCCCEEEECCCCCCCCCHHCHHHHHHHHCCEEEEEEEEEECCCCCEEE
AAEINLTHTFEKGQGYVALSRLKSLTGLRLLGFNEQALELDALALKADKRFQELSQEAED
EEEEEEEEEEECCCCEEHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFAEIDLADQHKAFIRHCGGTLNETEISRNEKKLLKGAKQNYGSATLDETRALFEEGYEI
HHHCCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCE
QDIAVERGLTPATIINHLARLQKEQGLDISVAHPGEEVVEQIRKLYKRVQKSKRPENFND
EEHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
DGSIKLKPIVELTSPRMGYDQVRLALLFIE
CCCEEEEEEEEECCCCCCHHHEEEEEEEEC
>Mature Secondary Structure
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYINYLKVRKVPVAVTASTGIAATHMNGM
CCHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCEEEEEECCCEEEEECCCE
TIHTWAGIGIKDRLSDDDLKRMKERKYLKEHLENAQVLIIDEISMLHAKQLNLVNQVLKY
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
FKESDEAFGGIQVIVAGDFFQLPPVGKNDERNRDKFCFMSDAWVEAKFRVCYLTEQHRQD
HHHCCCCCCCEEEEEECCEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEHHCCCH
DEILNQILNAIRAQNIQNEHKHALLTSRQHNIGETFTRLYTHNMDVDNINFQHLNEIENE
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
SHQFNAVLDGNDKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEE
CCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCC
DDEHGILPKVKMTDGTTLLVEPETWSIENEAGKSIASFQQIPLRLAWAITIHKSQGMTLE
CCCCCCCCEEEECCCCEEEECCCCCCCCCHHCHHHHHHHHCCEEEEEEEEEECCCCCEEE
AAEINLTHTFEKGQGYVALSRLKSLTGLRLLGFNEQALELDALALKADKRFQELSQEAED
EEEEEEEEEEECCCCEEHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFAEIDLADQHKAFIRHCGGTLNETEISRNEKKLLKGAKQNYGSATLDETRALFEEGYEI
HHHCCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCE
QDIAVERGLTPATIINHLARLQKEQGLDISVAHPGEEVVEQIRKLYKRVQKSKRPENFND
EEHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
DGSIKLKPIVELTSPRMGYDQVRLALLFIE
CCCEEEEEEEEECCCCCCHHHEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA