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The map label for this gene is mgtC [H]

Identifier: 50085120

GI number: 50085120

Start: 1972389

End: 1973111

Strand: Reverse

Name: mgtC [H]

Synonym: ACIAD1983

Alternate gene names: 50085120

Gene position: 1973111-1972389 (Counterclockwise)

Preceding gene: 50085121

Following gene: 50085115

Centisome position: 54.83

GC content: 42.05

Gene sequence:

>723_bases
ATGATGACTTTACAAGTTTTACAAAATACCAGTTTGTCCAATATGGCTGATACCTTGATTAGCTTGGCAGTTGCATTTAT
TTTAGGCGGATTGATTGGCTTTGAGCGACAATATCGGCAGCGTACAGCTGGATTACGTACCAATGTGCTGGTTGCCCTTG
GTGCAGCAATTTTTGTTGATATTGCGAATAACCTTTCAGGTGCGGATGGGGCTGTTCGTGTTATCGCTTATGTCGTATCT
GGCATTGGTTTTCTTGGCGCAGGTGTGATTATGCGCCAAGAAGGCAACATCCATGGTTTAAATACAGCAGCAACACTTTG
GTGTTCTGCTGCTATTGGTGCTGCGGCGGGCTCAGATCAAATTGTAGAAGCGGTAGTTGCAACAGCATTTATTCTGGCTG
CCAATACATTGCTTCGGCCTTTGGTCAATATGATTGATCGCCAACCGCTTGATGCAGAATCTGAAGTGACGCATATCATT
TATTTAGTTGCCAATAAGGCTCATCGTAAACTGGTGATGTATAAATTGACTGAGATCCTGCAGCATTTTAATTATCCATT
AAAGGATTTGGATGTGGAGCCATTTGGTGACAATGATATTGAAATTGAAGCAACACTCATTGCGACCTCGATTGATCCAG
TTGAAATGAATGAAATCATTACACAGATCAATCAGGTACCCCAAGTACAGCAAGCTTATTGGGATAAAAATACGATGGCT
TAG

Upstream 100 bases:

>100_bases
TACTTCTTATATCTACCTTTTATTTTGTTTGCCTATATGTGTTTGACTCAATGGGTTAAGCGTATGTATATCCGTCGTTA
CGGATGGCAATAAGAGCAAT

Downstream 100 bases:

>100_bases
GCATCGTATTTTTGATGACAAGTAGGAATTAAGATTTTTTAAATTTTGTTTTGAGAACCATTGAAACAATCACACCGACG
ATCAGCCCCCAGAAGGCCGA

Product: magnesium ABC transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MMTLQVLQNTSLSNMADTLISLAVAFILGGLIGFERQYRQRTAGLRTNVLVALGAAIFVDIANNLSGADGAVRVIAYVVS
GIGFLGAGVIMRQEGNIHGLNTAATLWCSAAIGAAAGSDQIVEAVVATAFILAANTLLRPLVNMIDRQPLDAESEVTHII
YLVANKAHRKLVMYKLTEILQHFNYPLKDLDVEPFGDNDIEIEATLIATSIDPVEMNEIITQINQVPQVQQAYWDKNTMA

Sequences:

>Translated_240_residues
MMTLQVLQNTSLSNMADTLISLAVAFILGGLIGFERQYRQRTAGLRTNVLVALGAAIFVDIANNLSGADGAVRVIAYVVS
GIGFLGAGVIMRQEGNIHGLNTAATLWCSAAIGAAAGSDQIVEAVVATAFILAANTLLRPLVNMIDRQPLDAESEVTHII
YLVANKAHRKLVMYKLTEILQHFNYPLKDLDVEPFGDNDIEIEATLIATSIDPVEMNEIITQINQVPQVQQAYWDKNTMA
>Mature_240_residues
MMTLQVLQNTSLSNMADTLISLAVAFILGGLIGFERQYRQRTAGLRTNVLVALGAAIFVDIANNLSGADGAVRVIAYVVS
GIGFLGAGVIMRQEGNIHGLNTAATLWCSAAIGAAAGSDQIVEAVVATAFILAANTLLRPLVNMIDRQPLDAESEVTHII
YLVANKAHRKLVMYKLTEILQHFNYPLKDLDVEPFGDNDIEIEATLIATSIDPVEMNEIITQINQVPQVQQAYWDKNTMA

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=112, Percent_Identity=46.4285714285714, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25952; Mature: 25952

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLQVLQNTSLSNMADTLISLAVAFILGGLIGFERQYRQRTAGLRTNVLVALGAAIFVD
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IANNLSGADGAVRVIAYVVSGIGFLGAGVIMRQEGNIHGLNTAATLWCSAAIGAAAGSDQ
HHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVEAVVATAFILAANTLLRPLVNMIDRQPLDAESEVTHIIYLVANKAHRKLVMYKLTEIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHH
QHFNYPLKDLDVEPFGDNDIEIEATLIATSIDPVEMNEIITQINQVPQVQQAYWDKNTMA
HHCCCCHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCC
>Mature Secondary Structure
MMTLQVLQNTSLSNMADTLISLAVAFILGGLIGFERQYRQRTAGLRTNVLVALGAAIFVD
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IANNLSGADGAVRVIAYVVSGIGFLGAGVIMRQEGNIHGLNTAATLWCSAAIGAAAGSDQ
HHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVEAVVATAFILAANTLLRPLVNMIDRQPLDAESEVTHIIYLVANKAHRKLVMYKLTEIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHH
QHFNYPLKDLDVEPFGDNDIEIEATLIATSIDPVEMNEIITQINQVPQVQQAYWDKNTMA
HHCCCCHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA