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The map label for this gene is livH [H]

Identifier: 50085079

GI number: 50085079

Start: 1929536

End: 1930417

Strand: Reverse

Name: livH [H]

Synonym: ACIAD1940

Alternate gene names: 50085079

Gene position: 1930417-1929536 (Counterclockwise)

Preceding gene: 50085080

Following gene: 50085078

Centisome position: 53.64

GC content: 41.04

Gene sequence:

>882_bases
ATGAATTTTTTTCTAGAAGTGCTGCTCGGTGGAACACTGGCAGGTGTGATGTATTCACTTGTGGCGATAGGCTTTGTTCT
TATTTATAGAGCCTCGGGAGTTTTTAACTTTGCGCAAGGTGCATTGGTGCTATTTTCAGCATTAACCTTTGTGAATTTAA
CTGAACACGGTGTGCCTTTTATCGTTGCCTTTGCAGTCACCTTATTTATTATTTTTATTGTGGTGTTACTCATTGATGCA
TTGGTGTTAAAGCATCTAGTGAATCGTTCAGTGATTACGCTTTTTATGGCGACATTAGGCTTAAGTTATGTGCTTGAGGG
GACTGCACAAGCAGTATGGGGAACACAGGTACATGGGCTCGACTTGGGAATTAGTGATGTTCCTATCGACTTTTATGGAA
TCCATCTAAGTAAATTTGATCTTGTTGCAACTTTGATTGCAGGCAGTCTTGTCATTATTTTATCGTTTTTATTTACCAAG
ACTCGATTTGGTATATCGCTTAGAGCAGTTGCTGATGATCCTTTGGCTTCACAATCTGTCGGAATTCGATTGAATTACAT
CTGGATTTTGGTGTGGAGTGTCGCTGGATTAGTTGCACTGGTCGCTGGATTACTCTGGGGCGCACGTTTAGGTGTGCAAT
TTTCACTGTCACTCGTGGTTTTAAAAGCATTACCTGTATTGATCATTGGTGGATTTACGTCCATTACGGGTGCCATTGTA
GGTGGTTTGATTATTGGTGCGAGTGAAAAGCTTGCCGAGATTTATCTAGGAAGTTTGATCGGGAGTGGCATAGAAAACTG
GTTTCCATACCTCATCGCAATTTTATTTTTACTGATACGTCCGACAGGGCTATTTGGTGAACAACAAGTTGCGAGGGTAT
AA

Upstream 100 bases:

>100_bases
GCAGAGTATTCAGGCGCAGCCAGAAGTGTTGCAAGTTTATTTAGGGATTGATGTAGGCCAAGTTGCGGTCTAGTTCATTG
ATTTAAAATAAGAGAAATAT

Downstream 100 bases:

>100_bases
CGATGTTTTTATTTTCTCAAGCTGAACAGTTTATTCGTCGTTATCAGGATGAAAAAAGAATTTTTGCGCTCAAACAACAT
CGCATATTGTTCTGGTTTTT

Product: branched chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNFFLEVLLGGTLAGVMYSLVAIGFVLIYRASGVFNFAQGALVLFSALTFVNLTEHGVPFIVAFAVTLFIIFIVVLLIDA
LVLKHLVNRSVITLFMATLGLSYVLEGTAQAVWGTQVHGLDLGISDVPIDFYGIHLSKFDLVATLIAGSLVIILSFLFTK
TRFGISLRAVADDPLASQSVGIRLNYIWILVWSVAGLVALVAGLLWGARLGVQFSLSLVVLKALPVLIIGGFTSITGAIV
GGLIIGASEKLAEIYLGSLIGSGIENWFPYLIAILFLLIRPTGLFGEQQVARV

Sequences:

>Translated_293_residues
MNFFLEVLLGGTLAGVMYSLVAIGFVLIYRASGVFNFAQGALVLFSALTFVNLTEHGVPFIVAFAVTLFIIFIVVLLIDA
LVLKHLVNRSVITLFMATLGLSYVLEGTAQAVWGTQVHGLDLGISDVPIDFYGIHLSKFDLVATLIAGSLVIILSFLFTK
TRFGISLRAVADDPLASQSVGIRLNYIWILVWSVAGLVALVAGLLWGARLGVQFSLSLVVLKALPVLIIGGFTSITGAIV
GGLIIGASEKLAEIYLGSLIGSGIENWFPYLIAILFLLIRPTGLFGEQQVARV
>Mature_293_residues
MNFFLEVLLGGTLAGVMYSLVAIGFVLIYRASGVFNFAQGALVLFSALTFVNLTEHGVPFIVAFAVTLFIIFIVVLLIDA
LVLKHLVNRSVITLFMATLGLSYVLEGTAQAVWGTQVHGLDLGISDVPIDFYGIHLSKFDLVATLIAGSLVIILSFLFTK
TRFGISLRAVADDPLASQSVGIRLNYIWILVWSVAGLVALVAGLLWGARLGVQFSLSLVVLKALPVLIIGGFTSITGAIV
GGLIIGASEKLAEIYLGSLIGSGIENWFPYLIAILFLLIRPTGLFGEQQVARV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=313, Percent_Identity=24.9201277955272, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31330; Mature: 31330

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
>Mature Secondary Structure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HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]