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The map label for this gene is lytT [H]

Identifier: 49188255

GI number: 49188255

Start: 5152512

End: 5153228

Strand: Reverse

Name: lytT [H]

Synonym: BAS5270

Alternate gene names: 49188255

Gene position: 5153228-5152512 (Counterclockwise)

Preceding gene: 49188256

Following gene: 49188254

Centisome position: 98.56

GC content: 29.15

Gene sequence:

>717_bases
ATGAAAATTTTACTGATTATGGAAGAAGCAGAAGAGCGAAGAAGTTTGGCTGAAAAATTTATTGAAAATATAAAGAATGT
AGAATGTTTTGAAGCAAGTATGGGAACAGAAGCACTATTTATCATGAAAAAGCATACACCAGATTTTGTTTTTTTAAACT
CAAAATTAATGGATGGAACTGGATTTGAATATGTGAATTTATTAAGGGAAGTAAATTGTTATGCAAAATTTATTTTTATG
GGTGAAGATATAGAAGAATCCATTACGGCATTTCGTTTTCAAGCATTTTATTATTTACTACGCCCATTTCGCGAAGAAGA
TTTGCAATTCCTTTTATATAGAATGGGTAAAGAGCAAGGAGAGAAAGCAAAGAGTTATTTGCGAAAACTACCGATAGAAG
GTCAAGAAGGAATTCGGTATATTTTTCCGGAAGATATTGTATATGTAAGCAAAAATAAGGAAAACAAAACAGTTTCAATT
TATACAACAAATAATCAGTATATTTCAACATATACACTTCAGGAGCTAGAAAATAAGCTAAATGCATATGATTTTTTACG
TGTGCATAAAAGTTATTTAATTAATATGTCATATGTACAAGAGTTAAAGCCTTACTATAATGGCACATATAATCTATATT
TAGATAAATATGATGAGCAACCGATTCCAGTTAGTCGTAATTATGTGAAACGACTTCGAAATAAAATTGAATTGTAG

Upstream 100 bases:

>100_bases
TTTAGATAAATAATGGTATAGTAAGAAAAAGGGAATGTTCTTTATAAAAGCGAATGTATACAACAGGACATACGGACAAA
AGAATTAGGTGGTTGAAGAA

Downstream 100 bases:

>100_bases
CAGATAATGCAATTTTTTTAACATGATAAACTAAAAATCCTTCATGATAGGGAGGATTCAAGTTAAATATTCAGAAAATT
TAGTACAATCCCACTAAGAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGTGFEYVNLLREVNCYAKFIFM
GEDIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQGEKAKSYLRKLPIEGQEGIRYIFPEDIVYVSKNKENKTVSI
YTTNNQYISTYTLQELENKLNAYDFLRVHKSYLINMSYVQELKPYYNGTYNLYLDKYDEQPIPVSRNYVKRLRNKIEL

Sequences:

>Translated_238_residues
MKILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGTGFEYVNLLREVNCYAKFIFM
GEDIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQGEKAKSYLRKLPIEGQEGIRYIFPEDIVYVSKNKENKTVSI
YTTNNQYISTYTLQELENKLNAYDFLRVHKSYLINMSYVQELKPYYNGTYNLYLDKYDEQPIPVSRNYVKRLRNKIEL
>Mature_238_residues
MKILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGTGFEYVNLLREVNCYAKFIFM
GEDIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQGEKAKSYLRKLPIEGQEGIRYIFPEDIVYVSKNKENKTVSI
YTTNNQYISTYTLQELENKLNAYDFLRVHKSYLINMSYVQELKPYYNGTYNLYLDKYDEQPIPVSRNYVKRLRNKIEL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=246, Percent_Identity=27.6422764227642, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788724, Length=250, Percent_Identity=24.8, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28516; Mature: 28516

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGT
CEEEEEEHHHHHHHHHHHHHHHHHCCCEEHHHCCCCEEEEEEEECCCCEEEEECEECCCC
GFEYVNLLREVNCYAKFIFMGEDIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQG
CHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCC
EKAKSYLRKLPIEGQEGIRYIFPEDIVYVSKNKENKTVSIYTTNNQYISTYTLQELENKL
HHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHHH
NAYDFLRVHKSYLINMSYVQELKPYYNGTYNLYLDKYDEQPIPVSRNYVKRLRNKIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGT
CEEEEEEHHHHHHHHHHHHHHHHHCCCEEHHHCCCCEEEEEEEECCCCEEEEECEECCCC
GFEYVNLLREVNCYAKFIFMGEDIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQG
CHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCC
EKAKSYLRKLPIEGQEGIRYIFPEDIVYVSKNKENKTVSIYTTNNQYISTYTLQELENKL
HHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHHH
NAYDFLRVHKSYLINMSYVQELKPYYNGTYNLYLDKYDEQPIPVSRNYVKRLRNKIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]