Click here to switch to the map view.

The map label for this gene is murA2

Identifier: 49188169

GI number: 49188169

Start: 5063148

End: 5064437

Strand: Reverse

Name: murA2

Synonym: BAS5183

Alternate gene names: 49188169

Gene position: 5064437-5063148 (Counterclockwise)

Preceding gene: 49188170

Following gene: 49188168

Centisome position: 96.86

GC content: 41.09

Gene sequence:

>1290_bases
ATGGAAAAATTGCTAATTGAAGGCGGAAGAGCTTTAAATGGAACAATTCGCGTGAGTGGTGCAAAGAACAGCGCCGTTGC
ATTAATTCCAGCGACAATTTTAGCAGATACTCCAGTAACTATTGGTGGTGTCCCTAATATTTCGGACGTGAAAATGTTAG
GAGACTTACTAGAGGAAATTGGAGGAAGAGTAACGTATGGACAGGAGGAAGAGATGGTAGTCGATCCTTCTAACATGGTT
GCAATGCCTTTACCAAACGGAAAAGTGAAAAAATTGCGTGCTTCTTATTATTTAATGGGTGCGATGCTTGGCCGTTTTAA
AAAAGCTGTTATTGGGCTTCCAGGTGGATGTCACTTAGGACCGAGGCCAATTGATCAGCATATTAAAGGGTTTGAAGCGT
TAGGTGCACATGTTACGAATGAACAAGGTGCTATCTATTTAAGAGCAGATGAACTACGCGGGGCTCGTATTTATTTAGAT
GTTGTTAGTGTAGGAGCTACGATTAATATTATGCTAGCAGCTGTACGAGCGAAAGGTAGAACTGTTATTGAAAACGCAGC
GAAAGAACCAGAGATTATTGATGTAGCTACACTGTTAACTAGCATGGGAGCACGTATTAAAGGTGCTGGTACAGATGTAA
TCCGAATTGATGGTGTGGATTCATTGCACGGTTGTCATCATACGATCATTCCAGATCGTATTGAAGCGGGTACGTATATG
ATTTTAGGTGCTGCATCAGGAGGAGAAGTAACAGTTGATAATGTTATTCCTCAGCACTTAGAGTCAGTTACGGCGAAGCT
CCGAGAAGCTGGTGTCCAGGTTGAAACGAATGATGACCAGATTACAGTGAACGGTGATAGAAGATTAAAAGTAGTTGATA
TAAAAACGCTTGTATATCCAGGTTTCCCAACAGACTTACAACAGCCGTTTACAACACTTTTAACAAAGGCGCATGGAACG
GGTGTTGTAACGGATACGATTTATGGTGCACGTTTTAAACATATTGATGAATTACGTCGTATGAATGCACAAATTAAAGT
AGAAGGTCGATCAGCTATCGTAACTGGTCCTGTTTTATTGCAAGGTGCAAAAGTGAAAGCGAGTGATTTGCGAGCTGGAG
CAGCACTTGTTATCGCAGGATTAATGGCGGATGGAATTACAGAAGTAACCGGACTTGAGCATATTGATCGAGGTTATGAA
AATATAGTAGACAAGCTTAAAGGGCTTGGTGCAAACATTTGGCGAGAACAAATGACAAAGCAAGAAATTGAAGAAATGAA
GAACGCATAA

Upstream 100 bases:

>100_bases
ATTTATTGAGTTTTGGGATGGAAAAGTAATTGAGATTCTTAAGGGGGAGCTTTCTATAAAAATATAGAAAGTAAATACAT
TCACAAGAAGGGAGCTCAAT

Downstream 100 bases:

>100_bases
GTGATACTTCCGCAAGGGGGAAGCGAAGCATCACTACTTGCGGAAGTACACTTTATAGAAAAAACACGGTTCACAAAATA
CGGCAGAAATATAAAGACTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA

Sequences:

>Translated_429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA
>Mature_429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=44.3645083932854, Blast_Score=350, Evalue=7e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_BACAN (Q81JW5)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847735.1
- RefSeq:   YP_022730.1
- RefSeq:   YP_031422.1
- ProteinModelPortal:   Q81JW5
- SMR:   Q81JW5
- EnsemblBacteria:   EBBACT00000010839
- EnsemblBacteria:   EBBACT00000015800
- EnsemblBacteria:   EBBACT00000023203
- GeneID:   1085274
- GeneID:   2821084
- GeneID:   2853124
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5578
- KEGG:   bar:GBAA_5578
- KEGG:   bat:BAS5183
- TIGR:   BA_5578
- TIGR:   GBAA_5578
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG482701
- OMA:   IGGKVTY
- ProtClustDB:   PRK12830
- BioCyc:   BANT260799:BAS5183-MONOMER
- BioCyc:   BANT261594:GBAA5578-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45867; Mature: 45867

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCEECCEEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEHEEEHHHCCC
TVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLL
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHEE
QGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTK
ECCCEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC
>Mature Secondary Structure
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCEECCEEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEHEEEHHHCCC
TVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLL
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHEE
QGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTK
ECCCEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629