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The map label for this gene is yybE [H]

Identifier: 49188055

GI number: 49188055

Start: 4944216

End: 4945100

Strand: Direct

Name: yybE [H]

Synonym: BAS5069

Alternate gene names: 49188055

Gene position: 4944216-4945100 (Clockwise)

Preceding gene: 49188053

Following gene: 49188059

Centisome position: 94.56

GC content: 37.85

Gene sequence:

>885_bases
ATGGAACTTCTTCAACTAAAATACTTTCAAACAGTCGCAAGATTAGAGCATATGACAAAAGCCGCTGAAGAATTGCATAT
CGCACAACCTTCGCTCAGCAAAACAATTGCTAGATTAGAAAAGGACTTAGGCGTTCCGTTATTTGACCGCCAAGGGCGAC
AAATTACATTAAACCCTTTCGGGAAAGTATTTTTAAAACGAGTAGAGCGCATTTTTCATGAATTAAGTGAAGGCGAACGA
GAAATTAAAGATTTAGCTGACTTACAACAAAGCTCTATTACGCTGGCTGTTTCTATTCCAAGAATATTACCAGAACTAAT
CGGTTCTTTTTTACTAGAACATCCTAACGTTCGATTCCAGCAATTTCTCGCATCTACTCCTTCTATGAAACGACAACTAG
ATAATATAGAAATTGACTTTTGTATTTCTTCTGTGCCAATTGAAGGCGAGGAAATTATTTGGGAGCCACTTATTACAGAA
GAAATTTTCTTAGTCGTCCCTTCAGGCCATCGTTTATCAGGACGTGAAAGTATCTATCTGCATGAAGTAAAAGACGAACC
GTTCATTAGTATGAACACTGGTTACGGATTTCGACACTTAACAGATGAATTTTGTAAAGAAGCTGGATTCACGCCACATA
TCGCTTTTGAAGTAGATGAACCAACCGTGATTAGCGATCTTATTAAGCAAGGCCTCGGCATCGCCTTTGTCCCAAGTTTA
ACTTTATTAAAAAACTCTACTTTAGCATTAAATAAGTTACGTATTATGGAACCCGTTTGTAAGCGAACGATTGGCTTAAG
CTGGTCCAAAAAACGTTACTTATCGAAAACCGCTCAGCAATTCCGTGAATTCGTGATAGATTACTTCTCCAATATTAAGG
CGTAA

Upstream 100 bases:

>100_bases
AATGGTTTAACAGATTTACTATACACGTCCATTTTCATACTGTATAATACATCTTTAATTATCAATTCATTCCTTTTGGT
CTATAGAAAGGAGAGTCAAA

Downstream 100 bases:

>100_bases
AATGATATCAATAAATAAAAGATGCCATCCCGATAGGGTGGCACCTTCTATTGTTCACTTTTCTCTAATTCTATTTCAGC
TAAAAGCGGTAGTACGTTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNPFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSGRESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIMEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA

Sequences:

>Translated_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNPFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSGRESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIMEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
>Mature_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNPFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSGRESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIMEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=30.0699300699301, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=26.4406779661017, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=24.9146757679181, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=25.2, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=27.3648648648649, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=25.0825082508251, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=27.5303643724696, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789204, Length=273, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788481, Length=285, Percent_Identity=23.1578947368421, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=30, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788297, Length=299, Percent_Identity=22.4080267558528, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=259, Percent_Identity=28.957528957529, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790208, Length=289, Percent_Identity=24.9134948096886, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789506, Length=293, Percent_Identity=22.5255972696246, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33673; Mature: 33673

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNPF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHH
GKVFLKRVERIFHELSEGEREIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITEEIFLVVPSGHRLSGRESIYL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCCEEEEEECCCCCCCCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLALNKLRIMEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNPF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHH
GKVFLKRVERIFHELSEGEREIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITEEIFLVVPSGHRLSGRESIYL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCCEEEEEECCCCCCCCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLALNKLRIMEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]