Click here to switch to the map view.

The map label for this gene is speH2

Identifier: 49188047

GI number: 49188047

Start: 4936441

End: 4936812

Strand: Direct

Name: speH2

Synonym: BAS5061

Alternate gene names: 49188047

Gene position: 4936441-4936812 (Clockwise)

Preceding gene: 49188046

Following gene: 49188051

Centisome position: 94.41

GC content: 36.02

Gene sequence:

>372_bases
ATGGAATATTCTACTTTCGGTAAGCATATAATAGTAGATTTGTGGGGAGTGGATTTTTCCCTATTAGATGATATGTACTT
TTTAGAACATCATTTAATTCACGCTGCCGATCTCTCGGGTGCCCATGTTTTAAACGTAAGTACAAAAGAATTTGATCCGC
ATGGCGTTACTGTTTTAGTTTTACTATCAGAAAGCCACCTCTCTATTCACACTTATCCAGAACAAAACTTTGCCGCCATT
GATTGTTATACGTGCGGTACAACCGTTGAACCGCAAATAGCGATTGATTATATCGTAAGTATATTGAAACCAAATGAGAT
GCATATAAGAAGATTAATTCGTGGTATAGGAGAGATTGTAAATACCGATTAA

Upstream 100 bases:

>100_bases
TAATTTCGCTCTCCTAAACTCAGAATCGAACCTTATCCTACACCAATGTTACAAAAAGGAAATGGAGTTTTGACGATATC
ACAGGAAGGAGTGCTACCTT

Downstream 100 bases:

>100_bases
ATATCACTCTTACTCATTTGTAAAAAGGAGGGTTGTAAATACCATCAGTGGAACGAATCCTCCACTGATGGTACAGACAC
ATACATAAAAAAACCTTGCA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC 2; SAMDC 2

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLVLLSESHLSIHTYPEQNFAAI
DCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIVNTD

Sequences:

>Translated_123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLVLLSESHLSIHTYPEQNFAAI
DCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIVNTD
>Mature_123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLVLLSESHLSIHTYPEQNFAAI
DCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIVNTD

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH2_BACAN (Q81X04)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847614.1
- RefSeq:   YP_022109.1
- RefSeq:   YP_031300.1
- ProteinModelPortal:   Q81X04
- SMR:   Q81X04
- EnsemblBacteria:   EBBACT00000009473
- EnsemblBacteria:   EBBACT00000017439
- EnsemblBacteria:   EBBACT00000022682
- GeneID:   1085056
- GeneID:   2819169
- GeneID:   2850561
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5446
- KEGG:   bar:GBAA_5446
- KEGG:   bat:BAS5061
- TIGR:   BA_5446
- TIGR:   GBAA_5446
- GeneTree:   EBGT00050000001345
- HOGENOM:   HBG485559
- OMA:   KPNEMHI
- ProtClustDB:   PRK01706
- BioCyc:   BANT260799:BAS5061-MONOMER
- BioCyc:   BANT261594:GBAA5446-MONOMER
- BRENDA:   4.1.1.50
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13878; Mature: 13878

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: ACT_SITE 65-65 ACT_SITE 70-70 ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEE
LLSESHLSIHTYPEQNFAAIDCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIV
EEECCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NTD
CCC
>Mature Secondary Structure
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEE
LLSESHLSIHTYPEQNFAAIDCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIV
EEECCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NTD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629