Click here to switch to the map view.

The map label for this gene is mta [H]

Identifier: 49188006

GI number: 49188006

Start: 4893282

End: 4894046

Strand: Reverse

Name: mta [H]

Synonym: BAS5020

Alternate gene names: 49188006

Gene position: 4894046-4893282 (Counterclockwise)

Preceding gene: 49188007

Following gene: 49188005

Centisome position: 93.6

GC content: 34.12

Gene sequence:

>765_bases
GTGATGGTAGTGATTTCAATACAACAATTGACGAGAGAAACAGGGGTTACGGTACGTACATTACGTTATTATGATCAAAT
AGATTTATTGAAGCCGAGTGGTAAAACAGAGGGTGGACATCGGTTATATAGTGAAGCTGACGTTATTCGTTTGCAACAAA
TTTTGTTTTTAAAGGAAATGGGATTTTCATTAAAAGAAACTGCGAATATGTTAGTAAAAGGTGAGCTCGATTTAAAAAAT
TCGCTTGAAAAACAACTTCGGTTTGTACAGGAAGAACAAAAGAAATTTAATCGAATGGAGAGTGTTTTACAAGCAGTTGT
TTATTCGGTAGATGTGGAAGGAGAACTCGATTGGAAAGTTATGTTTGAACTGATTCAGCTTTCGAAGCAGTCTTCTCGTA
TACGTGAAATATTTCAAAATGAAGTGTTTTCAAAGGAAGAACAAAAATTGCTTCATAATTTACCAAACATGAGTAAGGAA
GACCTGAATGTTTTAGAATGGGTAGATTTATTAAAGCAATTTCGTACTTTTATGAAAGATGGTAAAGAAGTAGCTAGTGA
TGAGGTACAAGGGGCAACGAAGAAATTAATGCAGAAATGTTTAGAAATGGCTAATGGTGATGAAGCGTTTTTAGATAAGT
TATGGGAAGTTAGAAAATCGAAGGAAGATTCACAGAAAATGAGCCTGTATCCGATTGAAGAAGAACTTTTACTATATATG
GATGAAGCTTTTCGTGTTTATGATGAAAAGGAGAGGGATAAATGA

Upstream 100 bases:

>100_bases
ATAAAAGCTGTTTATACAAAGAGTATAAACAGCTTTTTGTATTTTTTTACAAAAGGCTCGAAAGTTACGTAACGTCATCT
TTTATAATGAAGGGGAAGAG

Downstream 100 bases:

>100_bases
GTATGCTCGCAGAATATCGTTGGTATTTTTTAATTGGGGCAGAAATTGTATTTTGGTTATCGGCTATCGGTTTCTTTTTA
CTCCGTTACGGATTTCGTTT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MMVVISIQQLTRETGVTVRTLRYYDQIDLLKPSGKTEGGHRLYSEADVIRLQQILFLKEMGFSLKETANMLVKGELDLKN
SLEKQLRFVQEEQKKFNRMESVLQAVVYSVDVEGELDWKVMFELIQLSKQSSRIREIFQNEVFSKEEQKLLHNLPNMSKE
DLNVLEWVDLLKQFRTFMKDGKEVASDEVQGATKKLMQKCLEMANGDEAFLDKLWEVRKSKEDSQKMSLYPIEEELLLYM
DEAFRVYDEKERDK

Sequences:

>Translated_254_residues
MMVVISIQQLTRETGVTVRTLRYYDQIDLLKPSGKTEGGHRLYSEADVIRLQQILFLKEMGFSLKETANMLVKGELDLKN
SLEKQLRFVQEEQKKFNRMESVLQAVVYSVDVEGELDWKVMFELIQLSKQSSRIREIFQNEVFSKEEQKLLHNLPNMSKE
DLNVLEWVDLLKQFRTFMKDGKEVASDEVQGATKKLMQKCLEMANGDEAFLDKLWEVRKSKEDSQKMSLYPIEEELLLYM
DEAFRVYDEKERDK
>Mature_254_residues
MMVVISIQQLTRETGVTVRTLRYYDQIDLLKPSGKTEGGHRLYSEADVIRLQQILFLKEMGFSLKETANMLVKGELDLKN
SLEKQLRFVQEEQKKFNRMESVLQAVVYSVDVEGELDWKVMFELIQLSKQSSRIREIFQNEVFSKEEQKLLHNLPNMSKE
DLNVLEWVDLLKQFRTFMKDGKEVASDEVQGATKKLMQKCLEMANGDEAFLDKLWEVRKSKEDSQKMSLYPIEEELLLYM
DEAFRVYDEKERDK

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29956; Mature: 29956

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVVISIQQLTRETGVTVRTLRYYDQIDLLKPSGKTEGGHRLYSEADVIRLQQILFLKEM
CEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GFSLKETANMLVKGELDLKNSLEKQLRFVQEEQKKFNRMESVLQAVVYSVDVEGELDWKV
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MFELIQLSKQSSRIREIFQNEVFSKEEQKLLHNLPNMSKEDLNVLEWVDLLKQFRTFMKD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GKEVASDEVQGATKKLMQKCLEMANGDEAFLDKLWEVRKSKEDSQKMSLYPIEEELLLYM
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHH
DEAFRVYDEKERDK
HHHHHHHHHHHCCC
>Mature Secondary Structure
MMVVISIQQLTRETGVTVRTLRYYDQIDLLKPSGKTEGGHRLYSEADVIRLQQILFLKEM
CEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GFSLKETANMLVKGELDLKNSLEKQLRFVQEEQKKFNRMESVLQAVVYSVDVEGELDWKV
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MFELIQLSKQSSRIREIFQNEVFSKEEQKLLHNLPNMSKEDLNVLEWVDLLKQFRTFMKD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GKEVASDEVQGATKKLMQKCLEMANGDEAFLDKLWEVRKSKEDSQKMSLYPIEEELLLYM
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHH
DEAFRVYDEKERDK
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]