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The map label for this gene is hprK

Identifier: 49187998

GI number: 49187998

Start: 4883504

End: 4884433

Strand: Reverse

Name: hprK

Synonym: BAS5012

Alternate gene names: 49187998

Gene position: 4884433-4883504 (Counterclockwise)

Preceding gene: 49187999

Following gene: 49187997

Centisome position: 93.42

GC content: 38.82

Gene sequence:

>930_bases
ATGCCGAAAGTAAGGACAAAAGATTTGATTGAACAATTTCAATTGGAGTTAATAAGTGGTGAAGAAGGAATTCATCGTCC
GATTGATACAAGTGATTTATCACGACCTGGAATTGAAATGGCAGGATTTTTTACATATTATCCAGCTGATCGCGTGCAGC
TTCTTGGAAAGACGGAGCTTACATTCTTTGACACGTTAACGTCAGATCAAAAACAAGAGAGAATGAAAGCGCTTTGTACT
GAGGAGACGCCATGTATTATTGTAACTCGTAATCAAGATGTACCAGATGAGTTACTGCAAGCATCACGTGAATCAGGCAT
GCCTTTATTACGTTCTTCTCAAACGACAACAAGACTATCAAGTCGTTTAACAAATTATTTAGAAGGTAAGTTAGCGCCAA
CAACTGCCGTTCATGGTGTGTTAGTAGATATTTACGGCGTTGGTGTTTTAATTACAGGACAAAGTGGTGTCGGTAAAAGT
GAGACAGCTCTTGAGCTTGTAAAACGTGGTCATCGCCTTGTTGCGGATGATAGTGTAGAAATTCGCCAAGAAGATGAAGA
CATGTTAGTCGGAAGCTCACCAGATTTAATTGAGCATTTATTAGAAATTCGTGGTCTAGGCATTATTAACGTTATGACGT
TATTCGGTGCAGGAGCAGTGCGAAATTATAAGCGTATTACACTTGTTATTAATCTTGAAATTTGGGATCAAAAGAAAAAT
TATGATCGCTTAGGTCTTGATGAAGAGAAGATGAAGATTATTGATACAGAACTTACGAAGATTACACTTCCAGTTCGTCC
TGGTCGAAACTTAGCTGTTATTATTGAAGTGGCAGCGATGAACTTCCGTTTAAAACGTATGGGAGTCAATGCAGCACAGC
AGTTCTCAGAACGATTAATGAGTGCGATTGAGTTAGGAAATCAGGAGTAA

Upstream 100 bases:

>100_bases
CCGTATTTCTTGTTTCCAGAAAAAAATGGTACAATATCCGGTAGAATGGAATTTTACATCAAATGAGACTGAACCCGCAG
CGGAGTGGAGGTTTATACAT

Downstream 100 bases:

>100_bases
ACATTGGAGAGGGAGGTCATACATATGCTGTTAGGTTCTGTACCGCAGCTTGACCGCGTAGCTGTCCAACTTGGACCGTT
TCCTGTTTATTGGTACGGGA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCT
EETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKS
ETALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKN
YDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE

Sequences:

>Translated_309_residues
MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCT
EETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKS
ETALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKN
YDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE
>Mature_308_residues
PKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCTE
ETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSE
TALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKNY
DRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_BACAA (C3P0D0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002869382.1
- ProteinModelPortal:   C3P0D0
- SMR:   C3P0D0
- EnsemblBacteria:   EBBACT00000127700
- GeneID:   7852986
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_5422
- GeneTree:   EBGT00050000001684
- ProtClustDB:   PRK05428
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34587; Mature: 34456

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: ACT_SITE 138-138 ACT_SITE 159-159 ACT_SITE 177-177 ACT_SITE 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTEL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHEECCCCCE
TFFDTLTSDQKQERMKALCTEETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLS
EEEHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCHHHHHH
SRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSETALELVKRGHRLVADDSVE
HHHHHHHCCCCCCHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCE
IRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKN
ECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCC
YDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLM
CCCCCCCHHHHHHEECEEEEEEEECCCCCCEEEEEEEEHHCEEHHHHCCCHHHHHHHHHH
SAIELGNQE
HHHHCCCCC
>Mature Secondary Structure 
PKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTEL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHEECCCCCE
TFFDTLTSDQKQERMKALCTEETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLS
EEEHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCHHHHHH
SRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSETALELVKRGHRLVADDSVE
HHHHHHHCCCCCCHHHHHHHHEEEECCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCE
IRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKN
ECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCC
YDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLM
CCCCCCCHHHHHHEECEEEEEEEECCCCCCEEEEEEEEHHCEEHHHHCCCHHHHHHHHHH
SAIELGNQE
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA