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The map label for this gene is yvcI [H]

Identifier: 49187991

GI number: 49187991

Start: 4877065

End: 4877523

Strand: Reverse

Name: yvcI [H]

Synonym: BAS5005

Alternate gene names: 49187991

Gene position: 4877523-4877065 (Counterclockwise)

Preceding gene: 49187992

Following gene: 49187990

Centisome position: 93.28

GC content: 39.0

Gene sequence:

>459_bases
ATGCAAAGAGTGACAAACTGTGTGTTAATTAGAGATAATGAAGTACTCTTACTCCAAAAACCTCGTCGAAATTGGTGGGT
TGCACCAGGCGGGAAAATGGAGCGTGGTGAGACGGTAAGAGATTCCGTTGTCCGCGAGTACCGTGAGGAAACAGGTATTT
ATTTAAAGAACCCAGCGTTAAAGGGGGTCTTCACCTTTGTTATCCAAGAAGGTGATAAAGTTGTTTCTGAATGGATGATG
TTCTCCTTTTTAGCGACAGATTTTGCAGGAGAAAACAAACTAGAGAGCGAAGAAGGCATCATTGGCTGGCATACATTTGA
TAAAATTGATGATTTAGCAATGGCACCAGGAGATTATCACATTATTGATTATTTAATTAAAGGAAATGGAATAATCTACG
GTACATTTGTATATACCCCAGATTTTGAGTTGCTTTCATATCGATTAGATCCGAGTTAA

Upstream 100 bases:

>100_bases
AAAGAGGACTGGCTCCTTCGTTGTAGCAAACTGTTTTTGATAGTATAATGAAATGAGTATGCAGTGAGAAATTTGCTGCA
AGTAGCTGAGGTGAAGAAAC

Downstream 100 bases:

>100_bases
ACCGTCAAGGAGAGGATACGATGACAGAGAATAATGATATAAAAATGGTAATTATTACAGGAATGTCTGGAGCTGGAAAG
ACAGTAGCTTTACAAAGTTT

Product: mutT/nudix family protein

Products: CMP; diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MQRVTNCVLIRDNEVLLLQKPRRNWWVAPGGKMERGETVRDSVVREYREETGIYLKNPALKGVFTFVIQEGDKVVSEWMM
FSFLATDFAGENKLESEEGIIGWHTFDKIDDLAMAPGDYHIIDYLIKGNGIIYGTFVYTPDFELLSYRLDPS

Sequences:

>Translated_152_residues
MQRVTNCVLIRDNEVLLLQKPRRNWWVAPGGKMERGETVRDSVVREYREETGIYLKNPALKGVFTFVIQEGDKVVSEWMM
FSFLATDFAGENKLESEEGIIGWHTFDKIDDLAMAPGDYHIIDYLIKGNGIIYGTFVYTPDFELLSYRLDPS
>Mature_152_residues
MQRVTNCVLIRDNEVLLLQKPRRNWWVAPGGKMERGETVRDSVVREYREETGIYLKNPALKGVFTFVIQEGDKVVSEWMM
FSFLATDFAGENKLESEEGIIGWHTFDKIDDLAMAPGDYHIIDYLIKGNGIIYGTFVYTPDFELLSYRLDPS

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17548; Mature: 17548

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVTNCVLIRDNEVLLLQKPRRNWWVAPGGKMERGETVRDSVVREYREETGIYLKNPAL
CCCCCEEEEEECCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCH
KGVFTFVIQEGDKVVSEWMMFSFLATDFAGENKLESEEGIIGWHTFDKIDDLAMAPGDYH
HHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHEECCCCEE
IIDYLIKGNGIIYGTFVYTPDFELLSYRLDPS
EEEEEEECCCEEEEEEEECCCHHHEEEEECCC
>Mature Secondary Structure
MQRVTNCVLIRDNEVLLLQKPRRNWWVAPGGKMERGETVRDSVVREYREETGIYLKNPAL
CCCCCEEEEEECCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCH
KGVFTFVIQEGDKVVSEWMMFSFLATDFAGENKLESEEGIIGWHTFDKIDDLAMAPGDYH
HHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHEECCCCEE
IIDYLIKGNGIIYGTFVYTPDFELLSYRLDPS
EEEEEEECCCEEEEEEEECCCHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; H2O [C]

Specific reaction: CTP + H2O = CMP + diphosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]