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The map label for this gene is moaE [H]

Identifier: 49187609

GI number: 49187609

Start: 4513384

End: 4513848

Strand: Reverse

Name: moaE [H]

Synonym: BAS4616

Alternate gene names: 49187609

Gene position: 4513848-4513384 (Counterclockwise)

Preceding gene: 49187610

Following gene: 49187608

Centisome position: 86.33

GC content: 41.08

Gene sequence:

>465_bases
ATGACAAATACGTATTATGAAGTAATTGATACAGAAATCTCAATTGAAGAGGTAGCGAAGAGAGTAATTCGCCGCGAATG
TGGTGCTGTTACAACATTTATTGGAACGGTTAGAGAGTTTACGAAAGGGCGTCGTACATTATACTTAGAATATGTCGCTT
ATAAAACGATGGCAGAAAAGATGCTAGAGAAAATCGGATCAGAAGTGAAAGAGAAATGGCCAGGTACACACGTTGCGATT
ACACACCGCGTCGGTACACTACAAATTTCTGATATAGCGGTTGTTGTGGCTGTTTCAACGCCGCATCGTAAAGCGGCTTA
TGAAGCAAATGAATATATTATGGAACGCATAAAACAAATTGTTCCGATTTGGAAAAAGGAGTTTTGGGAAGATGGAGACT
CTTGGATTGGCGATCAATTAGAAAAAACGCCATATCCGGCGGGAGAGCCTGGGAAGGAGCTATAA

Upstream 100 bases:

>100_bases
ATGATGCTCCTGCAAACTTACGAGAAGAATATAAAGTATTTCATATAATAGAAGAAAAATTGTACATAGACTGGTTTTTA
CAAACGGTAAGGAGTGCGAA

Downstream 100 bases:

>100_bases
GTATGATTCGAGTATTGTTATTTGCGAACTTACAAGAAGAAGCAGGAAGAAGTGAATTACAAATAGAGAAAGAAAGTATT
ACGGTTGCAGAGTTAAAAGA

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTNTYYEVIDTEISIEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAI
THRVGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL

Sequences:

>Translated_154_residues
MTNTYYEVIDTEISIEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAI
THRVGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
>Mature_153_residues
TNTYYEVIDTEISIEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAIT
HRVGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=128, Percent_Identity=41.40625, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787003, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509279, Length=134, Percent_Identity=32.089552238806, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356259, Length=131, Percent_Identity=37.4045801526718, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17700; Mature: 17568

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTYYEVIDTEISIEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
MLEKIGSEVKEKWPGTHVAITHRVGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNTYYEVIDTEISIEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
MLEKIGSEVKEKWPGTHVAITHRVGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]