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The map label for this gene is pheA [H]

Identifier: 49187326

GI number: 49187326

Start: 4241995

End: 4242846

Strand: Reverse

Name: pheA [H]

Synonym: BAS4331

Alternate gene names: 49187326

Gene position: 4242846-4241995 (Counterclockwise)

Preceding gene: 49187327

Following gene: 49187322

Centisome position: 81.15

GC content: 40.14

Gene sequence:

>852_bases
ATGATTCGAGTAGGATATTTAGGACCAGAAGCAACATTTACAAATATGGCGGTGAGTCGTTTTTTTCCGGAAGCAGAGCA
TGTACCGTATCGAACGATTCCAGATTGTATGGATGCAGCTGCAAATGGAAATGTAGATTATGCAGTGGTACCACTAGAAA
ACGCCATAGAAGGTTCAGTGAATATAACAGTTGATTACCTCGTGCATGAGCAGCCGCTTTCTATTGTAGGAGAAATTACA
GTACCAATTCAGCAACATTTACTTGTACATCCGCAGTATGCAGACGTGTGGGAAGAAGTATATGCAGTACATTCTCATCC
ACACGCTATTGCCCAATGTCATAAATTTTTAAATGAAGAATTAAAGGGGGTAACTGCCCGAGATATGACATCAACAAGTG
CTGCTGCACAATATGTGAAAGAACATCCTGAAGAAAAAATCGCTGCCATTGCAAATGAAGCAGCTGCAGAAAAATACGGA
TTAACGATTGTAAGACGTGGCATCCATACACATAAAAATAATCATACACGCTTCCTCGTGCTCCATAAGAAAAAGAAAGC
AATACTCCCAAATAACGGAGAAAATCGCGGTGAGAAAACGACGCTTATGATAACGTTACCTGCTGATTATGCAGGGGCAC
TATATCAAGTGTTATCAGCTTTCGCATGGAGGAAATTAAATTTATCAAAAATCGAATCTCGTCCGATGAAAACAGGACTT
GGAAATTACTTTTTCTTAATCGATGTCGATAAAGCGTACGATGAGGTATTATTGCCAGGCGTAACGATGGAACTTGAAGC
ACTCGGTTTTTCTGTTACGGTGCTGGGGAGTTATTCTTCTTATTGGTTGTAA

Upstream 100 bases:

>100_bases
CTAGCGAATGCTAGTCTTTTTTAAATATTCAAAATTTACATAGAAGAATATAAAAAAGTATGGTATAACAGTAAGAAAAC
GAAAAAGAGGGGAAAAGACG

Downstream 100 bases:

>100_bases
AGAGGAGTATTTGTAATTAAGTTGATATAAATTCAGTCGCTAGTATATAAATAAAATCCCACCTATAAATGGTGGGATTT
TTTATTTTAACTTCGCAAGA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYADVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRGIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDEVLLPGVTMELEALGFSVTVLGSYSSYWL

Sequences:

>Translated_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYADVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRGIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDEVLLPGVTMELEALGFSVTVLGSYSSYWL
>Mature_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYADVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRGIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDEVLLPGVTMELEALGFSVTVLGSYSSYWL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=282, Percent_Identity=32.6241134751773, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324013, Length=280, Percent_Identity=30, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31550; Mature: 31550

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITVDYLVHEQPLSIVGEITVPIQQHLLVHPQYADVWEEVYAVHSHPHAIAQCHKFLNEE
EEEEEEEEECCCHHEEEEEEECCHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRRGIHTHKNNHTRFLV
HCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
GNYFFLIDVDKAYDEVLLPGVTMELEALGFSVTVLGSYSSYWL
CCEEEEEECCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITVDYLVHEQPLSIVGEITVPIQQHLLVHPQYADVWEEVYAVHSHPHAIAQCHKFLNEE
EEEEEEEEECCCHHEEEEEEECCHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRRGIHTHKNNHTRFLV
HCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
GNYFFLIDVDKAYDEVLLPGVTMELEALGFSVTVLGSYSSYWL
CCEEEEEECCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]