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The map label for this gene is yrvM [H]

Identifier: 49187292

GI number: 49187292

Start: 4206962

End: 4207729

Strand: Reverse

Name: yrvM [H]

Synonym: BAS4296

Alternate gene names: 49187292

Gene position: 4207729-4206962 (Counterclockwise)

Preceding gene: 49187293

Following gene: 49187289

Centisome position: 80.47

GC content: 36.98

Gene sequence:

>768_bases
ATGTTACATCAATTTTCACGTAATGAATTAGCCTTCGGTAAAGAAGGACTTGAAATATTAAAAAATAGTACAGTTGGTAT
TTTAGGAATTGGCGGCGTAGGTTCTTTTGCAGCTGAAGCGTTAGCGCGTTCTGGCGTAGGGCGTCTCGTATTAGTTGACA
AAGACGTTGTAGATATTACAAACGTGAACCGTCAAATTCATGCTTTAGTATCTACTGTAGGGCGTTCAAAAGTAGAATTA
ATGAAAGAGCGTATCGCAGACATTAACCCAGAGTGTGAAGTAATTGGACTAGAAATGTTTTATACAGATGAAACATATGA
AGAGTTCTTTAAGCATGGTTTAGACTTCGTAGTGGATGCATCTGATACGATTACGTTCAAAATTCATTTAATTAAACAAT
GTTTACGTCGTAAAATTAAAATTATCTCAAGTATGGGTGCAGCAAATAAAATGGATCCAACTCGTTTTCGTATTGCGGAC
ATCTCTAAAACACATACAGATCCAATTGCGAAAGTAATCCGTACGAAGCTTCGTAAAGAGGGCATTAAAAAAGGTGTGAA
AGTTGTTTTCTCTGACGAAAATCCAATCGTAATTCGTGAAGAAGTACGTAAAGAAATTGTACCAGACGAAAATGCAAAAA
TTCGTAAAGCGAAATTACCGCCTTCATCAAATGCATTCGTACCATCTGTGGCAGGCTTAATTATGGCAAGTCACGTTGTA
CGTGAACGCATTAAAAACGTAGAAGTGAAACGTGTAGGGCAAGAATAA

Upstream 100 bases:

>100_bases
ATATGTATTTTTAGGAATTCTATAACTTTTTCTATACAAATAGTCGGAAAAACGCTAGAATACATGGTAGACCATTTTTG
TAATAGGAGTGTAGAGCTGA

Downstream 100 bases:

>100_bases
AAAGAAAGCATATATCCGTCTAGGGTATATGCTTTTTCTATTATATTTTAAAGAACTGCTGATATTTGCAATGCTAATAC
TTCTTTATATAGCAGGTTTA

Product: hesA/moeB/thiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLHQFSRNELAFGKEGLEILKNSTVGILGIGGVGSFAAEALARSGVGRLVLVDKDVVDITNVNRQIHALVSTVGRSKVEL
MKERIADINPECEVIGLEMFYTDETYEEFFKHGLDFVVDASDTITFKIHLIKQCLRRKIKIISSMGAANKMDPTRFRIAD
ISKTHTDPIAKVIRTKLRKEGIKKGVKVVFSDENPIVIREEVRKEIVPDENAKIRKAKLPPSSNAFVPSVAGLIMASHVV
RERIKNVEVKRVGQE

Sequences:

>Translated_255_residues
MLHQFSRNELAFGKEGLEILKNSTVGILGIGGVGSFAAEALARSGVGRLVLVDKDVVDITNVNRQIHALVSTVGRSKVEL
MKERIADINPECEVIGLEMFYTDETYEEFFKHGLDFVVDASDTITFKIHLIKQCLRRKIKIISSMGAANKMDPTRFRIAD
ISKTHTDPIAKVIRTKLRKEGIKKGVKVVFSDENPIVIREEVRKEIVPDENAKIRKAKLPPSSNAFVPSVAGLIMASHVV
RERIKNVEVKRVGQE
>Mature_255_residues
MLHQFSRNELAFGKEGLEILKNSTVGILGIGGVGSFAAEALARSGVGRLVLVDKDVVDITNVNRQIHALVSTVGRSKVEL
MKERIADINPECEVIGLEMFYTDETYEEFFKHGLDFVVDASDTITFKIHLIKQCLRRKIKIISSMGAANKMDPTRFRIAD
ISKTHTDPIAKVIRTKLRKEGIKKGVKVVFSDENPIVIREEVRKEIVPDENAKIRKAKLPPSSNAFVPSVAGLIMASHVV
RERIKNVEVKRVGQE

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=198, Percent_Identity=40.9090909090909, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1787048, Length=143, Percent_Identity=34.965034965035, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082356, Length=130, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321790, Length=193, Percent_Identity=38.3419689119171, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6322825, Length=198, Percent_Identity=38.3838383838384, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321903, Length=146, Percent_Identity=28.0821917808219, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582879, Length=142, Percent_Identity=36.6197183098592, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24660640, Length=131, Percent_Identity=29.0076335877863, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28431; Mature: 28431

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHQFSRNELAFGKEGLEILKNSTVGILGIGGVGSFAAEALARSGVGRLVLVDKDVVDIT
CCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHH
NVNRQIHALVSTVGRSKVELMKERIADINPECEVIGLEMFYTDETYEEFFKHGLDFVVDA
HCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCEEEEC
SDTITFKIHLIKQCLRRKIKIISSMGAANKMDPTRFRIADISKTHTDPIAKVIRTKLRKE
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GIKKGVKVVFSDENPIVIREEVRKEIVPDENAKIRKAKLPPSSNAFVPSVAGLIMASHVV
HHHHCCEEEECCCCCEEEHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RERIKNVEVKRVGQE
HHHHHCCHHHHCCCC
>Mature Secondary Structure
MLHQFSRNELAFGKEGLEILKNSTVGILGIGGVGSFAAEALARSGVGRLVLVDKDVVDIT
CCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHH
NVNRQIHALVSTVGRSKVELMKERIADINPECEVIGLEMFYTDETYEEFFKHGLDFVVDA
HCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCEEEEC
SDTITFKIHLIKQCLRRKIKIISSMGAANKMDPTRFRIADISKTHTDPIAKVIRTKLRKE
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GIKKGVKVVFSDENPIVIREEVRKEIVPDENAKIRKAKLPPSSNAFVPSVAGLIMASHVV
HHHHCCEEEECCCCCEEEHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RERIKNVEVKRVGQE
HHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]