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The map label for this gene is cymR [H]

Identifier: 49187289

GI number: 49187289

Start: 4203993

End: 4204409

Strand: Reverse

Name: cymR [H]

Synonym: BAS4293

Alternate gene names: 49187289

Gene position: 4204409-4203993 (Counterclockwise)

Preceding gene: 49187292

Following gene: 49187288

Centisome position: 80.41

GC content: 41.73

Gene sequence:

>417_bases
ATGAAGATTTCAACGAAAGGCCGCTACGGCTTAACAATTATGATCGATCTTGCAAAAAAGTTTGGTGAAGGTCCGATTTC
ATTAAAATCAATTGCGCAGGCACATGACTTATCGGAACATTACTTAGAGCAATTAATTTCACCACTTCGTAACGCGCGTC
TAGTAAAGAGTACGCGCGGGGCATATGGCGGATATGTATTATCAGATCAGCCGGCTAACATTACAGCTGGGGATGTAATC
CGTGTGTTAGAGGGTCCGATTAGTGTTGTAGAAATGATAGAAGAAGAAGAGCCAGCACAACGCCAATTATGGATGCGTGT
TCGTGATGCGGTGCAAGAAGTGTTAGATAGTACAACGTTAGAAGATTTAGTACGTTATGAGGAAGAAAATCACGGGGGCT
ATATGTTTTACATTTAA

Upstream 100 bases:

>100_bases
TACTATATTATGCTATAATTTCATAGGATTTTAAATTGTGTTCTTTTATAAATAAGATATAACCAATAGAAGTGAAAATT
TGAAAAGAGGTGCAAAATAG

Downstream 100 bases:

>100_bases
TTCCTTGTGAAACGATTTGGAAAGAAGGAGATTTAATGGAACGCATTTACTTAGATCATGCTGCGACATCTCCGACTCAC
CTAGAAGTGGTCGAAAAGAT

Product: rrf2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAQAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMIEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENHGGYMFYI

Sequences:

>Translated_138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAQAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMIEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENHGGYMFYI
>Mature_138_residues
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAQAHDLSEHYLEQLISPLRNARLVKSTRGAYGGYVLSDQPANITAGDVI
RVLEGPISVVEMIEEEEPAQRQLWMRVRDAVQEVLDSTTLEDLVRYEEENHGGYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=32.8358208955224, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15571; Mature: 15571

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAQAHDLSEHYLEQLISPLRNARLVKSTRG
CCCCCCCCCCHHHHEEHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AYGGYVLSDQPANITAGDVIRVLEGPISVVEMIEEEEPAQRQLWMRVRDAVQEVLDSTTL
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
EDLVRYEEENHGGYMFYI
HHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMIDLAKKFGEGPISLKSIAQAHDLSEHYLEQLISPLRNARLVKSTRG
CCCCCCCCCCHHHHEEHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AYGGYVLSDQPANITAGDVIRVLEGPISVVEMIEEEEPAQRQLWMRVRDAVQEVLDSTTL
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
EDLVRYEEENHGGYMFYI
HHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]