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The map label for this gene is isdE [H]

Identifier: 49187261

GI number: 49187261

Start: 4175376

End: 4176323

Strand: Reverse

Name: isdE [H]

Synonym: BAS4265

Alternate gene names: 49187261

Gene position: 4176323-4175376 (Counterclockwise)

Preceding gene: 49187262

Following gene: 49187260

Centisome position: 79.87

GC content: 34.7

Gene sequence:

>948_bases
ATGAAAAAATCTATTACGCTATTCACAGCGATTTTATCTATTTTTTTCTTATTAATAGGTTGCAGTGCAAAAGGAGACGA
AAAAGCATCGGCAACAAAAACAGAAAAAGGAAAAGAGAAAATAGAAGTTACCGACCTGTCAGGAAGAAAGGTGACATTCG
ATAAAGTGCCAGAGAGTTTTGCGACATTAAGTATGGGAGACATGAATATTATTCATGCTTTAGGCGGAAAAATAGTAGGT
CGTCCGGATGCAAAAATAACTCTTCCAGAGGATATAAAGAAAATACAAGTAATCGGGAATGCACATCAGCCAAATTTTGA
GCAAATTGCTAGCTTAAAGCCTGATGTACTTATTGCTAACAATGGATTTCAAAAGAACATTCCAACGGTGGAAGGACAAG
GAACGAAAGTAATGATTTCTTCTGCGAATTCTGTACAAGATATTCAAAAGAATATTGAGCTATATGGAACGATAATGAAG
AAAGAAGATAAAGCAAACGAACTTAATCAAAAAATTAATGTTCAAATGAAGAAATATGAGAAAAAGAGCGATGTGAAAGC
ACTGCTAGTGTATGGAGCACCAGGTACATATTTAGCCGCATTACCAACCTCTTTATCAGGTGATATTTTAGAAAAGACAG
GCGGAAAAAATATCGCTGCTGATTTTCCAGAAATGAAGGAATATCCGCAATATGCGCAGCTAAGCGTAGAACGCATTATT
GAGGCAAATCCAGATGTGATTTATTTAATTACACATGGAGATCCAAATAGTGTTAAAAAAGCATTTGAAGGTGAAATGAT
GAAAAATGAAGCATGGAAAAATTTAGATGCAGTAAAACAAAATCGTGTAGTTATTTTGCCACCTGACTTATTTGGATCAA
ATCCTGGAACAAAAGTTACAGAAGCGATGGACTTTATGTATAAAAGTATACAAGATGTAAGGAAATGA

Upstream 100 bases:

>100_bases
TTTCTAGAAAATGTATGCGTTTTATATTGACAATGATAATCCTTATCAATTAAAGTAGAATAGTAGTTAATGATTATTAT
TATCAATTAGAGGTGAAAGA

Downstream 100 bases:

>100_bases
TAAGTATGGAAAGTAGTGAAGTAGTAAGGGAAGAGGAACATCCTTTTGCGAAAAAAAGATGGATCATAGCAGTTAGTTTA
GTTATATTAACGATTTTAGG

Product: iron compound ABC transporter iron compound-binding protein

Products: NA

Alternate protein names: Iron-regulated surface determinant protein E; Staphylococcal iron-regulated protein F [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKKSITLFTAILSIFFLLIGCSAKGDEKASATKTEKGKEKIEVTDLSGRKVTFDKVPESFATLSMGDMNIIHALGGKIVG
RPDAKITLPEDIKKIQVIGNAHQPNFEQIASLKPDVLIANNGFQKNIPTVEGQGTKVMISSANSVQDIQKNIELYGTIMK
KEDKANELNQKINVQMKKYEKKSDVKALLVYGAPGTYLAALPTSLSGDILEKTGGKNIAADFPEMKEYPQYAQLSVERII
EANPDVIYLITHGDPNSVKKAFEGEMMKNEAWKNLDAVKQNRVVILPPDLFGSNPGTKVTEAMDFMYKSIQDVRK

Sequences:

>Translated_315_residues
MKKSITLFTAILSIFFLLIGCSAKGDEKASATKTEKGKEKIEVTDLSGRKVTFDKVPESFATLSMGDMNIIHALGGKIVG
RPDAKITLPEDIKKIQVIGNAHQPNFEQIASLKPDVLIANNGFQKNIPTVEGQGTKVMISSANSVQDIQKNIELYGTIMK
KEDKANELNQKINVQMKKYEKKSDVKALLVYGAPGTYLAALPTSLSGDILEKTGGKNIAADFPEMKEYPQYAQLSVERII
EANPDVIYLITHGDPNSVKKAFEGEMMKNEAWKNLDAVKQNRVVILPPDLFGSNPGTKVTEAMDFMYKSIQDVRK
>Mature_315_residues
MKKSITLFTAILSIFFLLIGCSAKGDEKASATKTEKGKEKIEVTDLSGRKVTFDKVPESFATLSMGDMNIIHALGGKIVG
RPDAKITLPEDIKKIQVIGNAHQPNFEQIASLKPDVLIANNGFQKNIPTVEGQGTKVMISSANSVQDIQKNIELYGTIMK
KEDKANELNQKINVQMKKYEKKSDVKALLVYGAPGTYLAALPTSLSGDILEKTGGKNIAADFPEMKEYPQYAQLSVERII
EANPDVIYLITHGDPNSVKKAFEGEMMKNEAWKNLDAVKQNRVVILPPDLFGSNPGTKVTEAMDFMYKSIQDVRK

Specific function: Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors t

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019957
- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34699; Mature: 34699

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSITLFTAILSIFFLLIGCSAKGDEKASATKTEKGKEKIEVTDLSGRKVTFDKVPESF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCCHH
ATLSMGDMNIIHALGGKIVGRPDAKITLPEDIKKIQVIGNAHQPNFEQIASLKPDVLIAN
HEEECCCHHHHHHHCCEEECCCCCEEECHHHHHEEEEECCCCCCCHHHHHCCCCCEEEEC
NGFQKNIPTVEGQGTKVMISSANSVQDIQKNIELYGTIMKKEDKANELNQKINVQMKKYE
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
KKSDVKALLVYGAPGTYLAALPTSLSGDILEKTGGKNIAADFPEMKEYPQYAQLSVERII
CCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHH
EANPDVIYLITHGDPNSVKKAFEGEMMKNEAWKNLDAVKQNRVVILPPDLFGSNPGTKVT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCCCCCCCHHH
EAMDFMYKSIQDVRK
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKSITLFTAILSIFFLLIGCSAKGDEKASATKTEKGKEKIEVTDLSGRKVTFDKVPESF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCCHH
ATLSMGDMNIIHALGGKIVGRPDAKITLPEDIKKIQVIGNAHQPNFEQIASLKPDVLIAN
HEEECCCHHHHHHHCCEEECCCCCEEECHHHHHEEEEECCCCCCCHHHHHCCCCCEEEEC
NGFQKNIPTVEGQGTKVMISSANSVQDIQKNIELYGTIMKKEDKANELNQKINVQMKKYE
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
KKSDVKALLVYGAPGTYLAALPTSLSGDILEKTGGKNIAADFPEMKEYPQYAQLSVERII
CCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHH
EANPDVIYLITHGDPNSVKKAFEGEMMKNEAWKNLDAVKQNRVVILPPDLFGSNPGTKVT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCCCCCCCHHH
EAMDFMYKSIQDVRK
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA