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The map label for this gene is prmA

Identifier: 49187207

GI number: 49187207

Start: 4125741

End: 4126679

Strand: Reverse

Name: prmA

Synonym: BAS4211

Alternate gene names: 49187207

Gene position: 4126679-4125741 (Counterclockwise)

Preceding gene: 49187208

Following gene: 49187206

Centisome position: 78.92

GC content: 39.19

Gene sequence:

>939_bases
GTGAAATGGTCAGAAATTAGTATTCATACAACAGAAGAAGCAGTAGAAGCTGTCTCTCATATTTTACATGAAGCGGGTGC
TAGTGGAGTTGCGATTGAGGATCCAGCGGAGTTAACGAAAGAGCGCGAGCAACAATACGGTGAAATTTATGCATTGAACC
CAGATGAATATCCGGCGGAAGGTGTATTAATAAAAGCATACTTCCCGCAAACGGATTCTTTACATGAAACGATTGCAGGT
GTAAAGTCATCTATTGATGTGCTTCCATCTTACGACATCGAAATTGGTACTGGAAATATTACCGTTAACGAAGTCAATGA
AGAAGATTGGGCTACTGCTTGGAAAAAATATTACCATCCAGTACAAATTTCTGATACATTCACAATTGTACCGACTTGGG
AAGAATATACACCATCTTCTCCGGAAGAAAAAATTATTGAATTAGATCCAGGTATGGCGTTTGGGACAGGAACTCATCCA
ACAACGACGATGTGTATCCGTGCTTTAGAAAAAACAGTACAGCCAGGTGATACGATCATTGATGTAGGGACGGGTTCTGG
TGTACTGAGTATTGCAGCGGCAAAATTAGGTGCGTCTTCTGTTCAAGCCTATGATTTAGATCCGGTTGCAGTTGAAAGTG
CAGAAATGAATGTACGTTTAAATAAAACAGATGACGTCGTGTCTGTTGGACAAAATAGTCTTTTAGAAGGTATTGAAGGT
CCTGTTGATTTAATCGTAGCTAATTTATTAGCAGAAATTATTTTATTATTCCCTGAAGATGCAGCAAGAGTTGTGAAATC
AGGCGGATTATTTATTACATCGGGCATTATTGCTGCGAAGGAAAAGGTAATTTCTGAGGCACTAGAAAAAGCTGGATTTA
CAATTGAAGAAGTGTTACGAATGGAAGATTGGGTAGCAATTATTGCACGAAATGCGTAA

Upstream 100 bases:

>100_bases
GAATTTGCAGGGCAAGAAGAGCAGGATGATAGTTTATTCGGAAAGCTTAAACGTGCTTTCAAAGGGGAATAATGGAAATA
AAAAATGGAGTTGGTAAATT

Downstream 100 bases:

>100_bases
TATAGATTTTAGTCTATAATGAAAAGGGGGAGTCTCTCACTATAAGGTGAGGGACTTGCCGTTTGTTATATGAAAAATGA
TAACGTTTCGTTCTTTTCGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAG
VKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHP
TTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEG
PVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA

Sequences:

>Translated_312_residues
MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAG
VKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHP
TTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEG
PVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
>Mature_312_residues
MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAG
VKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHP
TTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEG
PVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=313, Percent_Identity=30.3514376996805, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACAA (C3P8L8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868601.1
- ProteinModelPortal:   C3P8L8
- SMR:   C3P8L8
- EnsemblBacteria:   EBBACT00000128375
- GeneID:   7851084
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4556
- GeneTree:   EBGT00050000002784
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33715; Mature: 33715

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAE
CCCCEEEEECHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHCCCEEEECCCCCCCC
GVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHP
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCHHHHHHHHHHCCC
VQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTII
EEECCEEEEEECHHHCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCEE
DVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEG
EECCCCCHHHHHHHHHCCCCCEEECCCCEEEECCEEEEEECCCCCHHHHCHHHHHHHCCC
PVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLR
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHH
MEDWVAIIARNA
HHHHHHEEECCC
>Mature Secondary Structure
MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAE
CCCCEEEEECHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHCCCEEEECCCCCCCC
GVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHP
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCHHHHHHHHHHCCC
VQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTII
EEECCEEEEEECHHHCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCEE
DVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEG
EECCCCCHHHHHHHHHCCCCCEEECCCCEEEECCEEEEEECCCCCHHHHCHHHHHHHCCC
PVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLR
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHH
MEDWVAIIARNA
HHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA