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The map label for this gene is ywcF [H]

Identifier: 49187062

GI number: 49187062

Start: 3994314

End: 3995492

Strand: Reverse

Name: ywcF [H]

Synonym: BAS4064

Alternate gene names: 49187062

Gene position: 3995492-3994314 (Counterclockwise)

Preceding gene: 49187063

Following gene: 49187061

Centisome position: 76.42

GC content: 35.28

Gene sequence:

>1179_bases
ATGAAAAGAAGTACCGAGTTTCTAAAAAGTTTAGATGTAAAATTAATATTAATTTTGTTTGCATTATGTGTCACGAGTAT
AGCTGCTATATATAGCAGTCAGCAAACTGGCCAATATGGAGAGGCAAACTTTGCGATGAAACAGGGTTTGAACTACATAA
TTGGGGTTGTATTGTTATTGCTTGTTGCAAGCATTGACTTAGATCAATTACAAAAATTGTCTTGGCCACTTTATATCGCT
GGATTTGCTTCACTTATTCTTTTAAAAATACTACCGGTTTCCACTTTCACACCTGAAAAATTAGGTGCAAAAAGATGGTT
TGTATTTCCGTTAGTTGGACAAATTCAACCATCTGAGTTTTTCAAAATTTCATTGCTTCTCGTAGTAGCAAGTATAGCAG
TGAAACATAATGCGCAGTATATGGCAAGGACATTCCAAACGGACTTAAAATTAGTAGGTAAAATTGTGTTAGTATCCCTC
CCGCCTATGGCTGTTGTATATAGCCAACCGGATACAGGGATGGTGTTCTTATATGCTGCTGCAATTGCATGTATTTTATT
TATGTCAGGTATTCAGAAGAAATTGATAGCGTTATGTACAGTTATTCCAGTCACCATACTATCTACGTTAATATTTATTT
ACGTAAGGTATGAGGATTTCTTCTTTAATAAGTTAGTTACGTTACTAAAACCTCACCAACAATCACGTATTTTAGGTTGG
TTAGATCCATTTGAACATACAGATCAAGGTTATCAAACACAGCAATCGATTTTAGCTGTAGGTAGTGGCGGTATGGAAGG
GAAAGGATTTGGAGAAGGCAACGTCTATATCCCTGAGAAGCATACTGACTTTATTTTCGCTACAATTGCCGAAGAAGGTG
GATTTATCGTAGCAGCGTTAGTTGTCTTCTTGTTCCTATTACTACTATATAGAACAATTATTATCGGTTATTCTGCTGAT
AATTTATTCGGTACATTATTATGTGCTGGGTCAATTGGGATATTAACGGTTCAAATATTCCAAAACATCGGTATGATCGT
TGGATTAATGCCTGTAAAAGGTATTGCATTACCTTTCTTATCATATGGGGGAAGTTCCTTGCTCTCGAATATGATTATGA
TGGGTCTCATATTATCGGTACGAAAAACGTATAAAAAGTATATGTTTTCCGTTAAGTAA

Upstream 100 bases:

>100_bases
TATAAGTGTTTTATAGATAATGTGTAATCAGTCGTCAAAACATGAAGAATGTTGACTCCTGGTTTTTTATTTTGCTGTAA
CAATGTTTCAGGAGGATGTC

Downstream 100 bases:

>100_bases
AAAAAGCTGATTCGTTTCTAAACGAATCAGCTTTTTTACATATATGTTAGCTACAGTAGATGAAGCACATAAAATAAATA
TTTTGTTAAAAAAATGAAAA

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKRSTEFLKSLDVKLILILFALCVTSIAAIYSSQQTGQYGEANFAMKQGLNYIIGVVLLLLVASIDLDQLQKLSWPLYIA
GFASLILLKILPVSTFTPEKLGAKRWFVFPLVGQIQPSEFFKISLLLVVASIAVKHNAQYMARTFQTDLKLVGKIVLVSL
PPMAVVYSQPDTGMVFLYAAAIACILFMSGIQKKLIALCTVIPVTILSTLIFIYVRYEDFFFNKLVTLLKPHQQSRILGW
LDPFEHTDQGYQTQQSILAVGSGGMEGKGFGEGNVYIPEKHTDFIFATIAEEGGFIVAALVVFLFLLLLYRTIIIGYSAD
NLFGTLLCAGSIGILTVQIFQNIGMIVGLMPVKGIALPFLSYGGSSLLSNMIMMGLILSVRKTYKKYMFSVK

Sequences:

>Translated_392_residues
MKRSTEFLKSLDVKLILILFALCVTSIAAIYSSQQTGQYGEANFAMKQGLNYIIGVVLLLLVASIDLDQLQKLSWPLYIA
GFASLILLKILPVSTFTPEKLGAKRWFVFPLVGQIQPSEFFKISLLLVVASIAVKHNAQYMARTFQTDLKLVGKIVLVSL
PPMAVVYSQPDTGMVFLYAAAIACILFMSGIQKKLIALCTVIPVTILSTLIFIYVRYEDFFFNKLVTLLKPHQQSRILGW
LDPFEHTDQGYQTQQSILAVGSGGMEGKGFGEGNVYIPEKHTDFIFATIAEEGGFIVAALVVFLFLLLLYRTIIIGYSAD
NLFGTLLCAGSIGILTVQIFQNIGMIVGLMPVKGIALPFLSYGGSSLLSNMIMMGLILSVRKTYKKYMFSVK
>Mature_392_residues
MKRSTEFLKSLDVKLILILFALCVTSIAAIYSSQQTGQYGEANFAMKQGLNYIIGVVLLLLVASIDLDQLQKLSWPLYIA
GFASLILLKILPVSTFTPEKLGAKRWFVFPLVGQIQPSEFFKISLLLVVASIAVKHNAQYMARTFQTDLKLVGKIVLVSL
PPMAVVYSQPDTGMVFLYAAAIACILFMSGIQKKLIALCTVIPVTILSTLIFIYVRYEDFFFNKLVTLLKPHQQSRILGW
LDPFEHTDQGYQTQQSILAVGSGGMEGKGFGEGNVYIPEKHTDFIFATIAEEGGFIVAALVVFLFLLLLYRTIIIGYSAD
NLFGTLLCAGSIGILTVQIFQNIGMIVGLMPVKGIALPFLSYGGSSLLSNMIMMGLILSVRKTYKKYMFSVK

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=341, Percent_Identity=32.5513196480938, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786277, Length=400, Percent_Identity=30.25, Blast_Score=131, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43273; Mature: 43273

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSTEFLKSLDVKLILILFALCVTSIAAIYSSQQTGQYGEANFAMKQGLNYIIGVVLLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
LVASIDLDQLQKLSWPLYIAGFASLILLKILPVSTFTPEKLGAKRWFVFPLVGQIQPSEF
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCHHH
FKISLLLVVASIAVKHNAQYMARTFQTDLKLVGKIVLVSLPPMAVVYSQPDTGMVFLYAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHH
AIACILFMSGIQKKLIALCTVIPVTILSTLIFIYVRYEDFFFNKLVTLLKPHQQSRILGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHECC
LDPFEHTDQGYQTQQSILAVGSGGMEGKGFGEGNVYIPEKHTDFIFATIAEEGGFIVAAL
CCCHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCHHHHH
VVFLFLLLLYRTIIIGYSADNLFGTLLCAGSIGILTVQIFQNIGMIVGLMPVKGIALPFL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SYGGSSLLSNMIMMGLILSVRKTYKKYMFSVK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRSTEFLKSLDVKLILILFALCVTSIAAIYSSQQTGQYGEANFAMKQGLNYIIGVVLLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
LVASIDLDQLQKLSWPLYIAGFASLILLKILPVSTFTPEKLGAKRWFVFPLVGQIQPSEF
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCHHH
FKISLLLVVASIAVKHNAQYMARTFQTDLKLVGKIVLVSLPPMAVVYSQPDTGMVFLYAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHH
AIACILFMSGIQKKLIALCTVIPVTILSTLIFIYVRYEDFFFNKLVTLLKPHQQSRILGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHECC
LDPFEHTDQGYQTQQSILAVGSGGMEGKGFGEGNVYIPEKHTDFIFATIAEEGGFIVAAL
CCCHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCHHHHH
VVFLFLLLLYRTIIIGYSADNLFGTLLCAGSIGILTVQIFQNIGMIVGLMPVKGIALPFL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SYGGSSLLSNMIMMGLILSVRKTYKKYMFSVK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]