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The map label for this gene is spoIIAB

Identifier: 49186982

GI number: 49186982

Start: 3925695

End: 3926135

Strand: Reverse

Name: spoIIAB

Synonym: BAS3984

Alternate gene names: 49186982

Gene position: 3926135-3925695 (Counterclockwise)

Preceding gene: 49186983

Following gene: 49186981

Centisome position: 75.09

GC content: 36.28

Gene sequence:

>441_bases
ATGAGAAATGAAATGAACCTTCAATTTTCGGCATTAAGTCAAAATGAATCGTTTGCTCGCGTTACAGTAGCTGCTTTCAT
TGCACAACTGGACCCAACGATGGAAGAACTTACGGAGATTAAAACAGTTGTGTCAGAAGCAGTTACAAATGCAATTATTC
ATGGGTACGAAGGAAATGCAGAAGGTGTTGTTTATATTTCTGTAATTTTGGAAGAAGCAATGGTGAAACTCACGATTCGA
GATGAAGGGATTGGCATCTTTAATTTAGATGAAGCGAGACAACCCCTTTTTACAACTAAACCTGAATTAGAGCGTTCCGG
AATGGGATTTACTATCATGGAAAATTTTATGGATGAAGTAGAAGTTATTTCAAACGAATCTTTCGGGACAACAATCCATT
TGACAAAATACTTATCAAATAGTAACGCTCTATGCAATTAA

Upstream 100 bases:

>100_bases
ACCTCCTGTTAAACGTTTATTTGAAATGTCGGGCTTATTTAAAATTGTTCGTCTAGAAGAAAGTGAAGCGCATGCGCTCG
CGACGTTGGGGGTGGCATAA

Downstream 100 bases:

>100_bases
GGAGAATAGCCTATGGACATAGAGGTCAAAAATGAGAAGAAGAAACCTCAGTTAAAGGACCACGAGCTAAAAGCGTTAAT
TCAAAAAAGTCAAGATGGAG

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNAEGVVYISVILEEAMVKLTIR
DEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEVEVISNESFGTTIHLTKYLSNSNALCN

Sequences:

>Translated_146_residues
MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNAEGVVYISVILEEAMVKLTIR
DEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEVEVISNESFGTTIHLTKYLSNSNALCN
>Mature_146_residues
MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNAEGVVYISVILEEAMVKLTIR
DEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEVEVISNESFGTTIHLTKYLSNSNALCN

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP2AB_BACAA (C3P7L0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868375.1
- ProteinModelPortal:   C3P7L0
- SMR:   C3P7L0
- EnsemblBacteria:   EBBACT00000124769
- GeneID:   7851714
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4317
- GeneTree:   EBGT00050000001549
- ProtClustDB:   PRK03660
- HAMAP:   MF_00637
- InterPro:   IPR010194
- InterPro:   IPR003594
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- TIGRFAMs:   TIGR01925

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.11.1

Molecular weight: Translated: 16247; Mature: 16247

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNA
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGVVYISVILEEAMVKLTIRDEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEV
CCEEEHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHH
EVISNESFGTTIHLTKYLSNSNALCN
HHHCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNA
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGVVYISVILEEAMVKLTIRDEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEV
CCEEEHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHH
EVISNESFGTTIHLTKYLSNSNALCN
HHHCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA