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The map label for this gene is malR [H]

Identifier: 49186917

GI number: 49186917

Start: 3867341

End: 3868372

Strand: Reverse

Name: malR [H]

Synonym: BAS3919

Alternate gene names: 49186917

Gene position: 3868372-3867341 (Counterclockwise)

Preceding gene: 49186918

Following gene: 49186914

Centisome position: 73.98

GC content: 36.63

Gene sequence:

>1032_bases
ATGACAGTTACAATTAAAGATGTGGCGAAGAAGGCGAATGTAGCACCATCTACCGTTTCTCGTGTAATTGCTGATAATCC
AAGTATAAGTGAAAAAACAAAGCGTCGTGTTCGGAAAGTGATGAGTGAACTAGGGTATCATCCAAATTTAAACGCAAGAA
ACCTAGCTAACCAAACAACAAAAACACTTGGCCTTGTTATGCCAAGTTCTGCAAGTAAAGCTTTTCAAAATCCTTTTTTC
CCAGAAGTTATAAGAGGAATTAGTTCATTTGCACATGTGGAAGGGTATGCGCTTTATATGTCGACAGGTGAAACGGAAGA
TGAAATTTTTAACGGTGTTGTAAAGATGGTGCAGGGGCGCCAAATTGGTGGCATTATTCTTTTATATTCAAGAGAGAATG
ATCGGATTATTCAATATTTACATAAACAAAATTTTCCGTTCGTATTAATTGGGAAACCATATGATCGTAAAGAAGAAATT
ACATATGTAGATAATGACAATTATACAGCTGCAAGAGAAGTGGCAGAATATTTGATTTCATTAGGTCATAAACAAATCGC
ATTCATCGGCGGTGGATCAGATTTACTTGTAACGAGAGATCGTTTGGCTGGTATGAGTGATGCTTTAAAATTAGCAGACA
TTGTATTGCCAAAAGAATATATTTTACATTTTGATTTTTCAAGAGAAAGTGGTCAACAAGCCGTTGAGGAATTAATGGGG
CTAAAGCAACCACCGACAGCAATTATGGCAACGGATGACTTGATTGGTCTTGGTGTGTTAAGTGCACTTTCTAAAAAAGG
ATTTGTTGTACCCAAGGATGTTTCAATTGTAAGTTTCAACAATGCTTTATTATCAGAAATTGCGAGTCCGCCACTCTCGA
CAGTTGATGTGAATATATACCAGCTAGGATATGAAGCTGCAAAAGCTTTAGTTGATAAAGTAGAGAATGCGGAGTCTACT
GCAAAGTGTATTATTATTCCGCATAAATTACTGAAGCGTCAAACTTGCGATCATTATGCAACAAAAAGCTAA

Upstream 100 bases:

>100_bases
AGATAGAATCAATGAAAGTTTATGACTTCCCCTATTACTTGCAACGGGTGCAAGATGAAAATATATAAAATGGCAGAGAA
GTGAAAGGAGGGGGATTTTT

Downstream 100 bases:

>100_bases
GAGTTTAACTCTTAGCTTTTTGTTGTAGAAAGGCTTCTAAACGGTCACAGCCTTCTTTTAAAGTTTCAATACTATATGCA
TAAGACAAGCGAAGGTAGCC

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEDEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHKQNFPFVLIGKPYDRKEEI
TYVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
LKQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAEST
AKCIIIPHKLLKRQTCDHYATKS

Sequences:

>Translated_343_residues
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEDEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHKQNFPFVLIGKPYDRKEEI
TYVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
LKQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAEST
AKCIIIPHKLLKRQTCDHYATKS
>Mature_342_residues
TVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFFP
EVIRGISSFAHVEGYALYMSTGETEDEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHKQNFPFVLIGKPYDRKEEIT
YVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMGL
KQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAESTA
KCIIIPHKLLKRQTCDHYATKS

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=33.8658146964856, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=28.9156626506024, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=28.2282282282282, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=28.1150159744409, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789068, Length=304, Percent_Identity=29.9342105263158, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=30.4794520547945, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788474, Length=339, Percent_Identity=28.023598820059, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=27.7611940298507, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787906, Length=340, Percent_Identity=23.5294117647059, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=25.3687315634218, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=24.6875, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=341, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786268, Length=300, Percent_Identity=26, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790689, Length=339, Percent_Identity=23.8938053097345, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37825; Mature: 37694

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTT
CEEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTLGLVMPSSASKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEDEIFNGVVKMVQGR
HHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLHKQNFPFVLIGKPYDRKEEITYVDNDNYTAAREVAEYLIS
CCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHH
LGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHC
LKQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIY
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCEEEEEHH
QLGYEAAKALVDKVENAESTAKCIIIPHKLLKRQTCDHYATKS
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTT
EEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTLGLVMPSSASKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEDEIFNGVVKMVQGR
HHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLHKQNFPFVLIGKPYDRKEEITYVDNDNYTAAREVAEYLIS
CCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHH
LGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHC
LKQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIY
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCEEEEEHH
QLGYEAAKALVDKVENAESTAKCIIIPHKLLKRQTCDHYATKS
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]