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The map label for this gene is cdd [H]

Identifier: 49184769

GI number: 49184769

Start: 1780263

End: 1780658

Strand: Direct

Name: cdd [H]

Synonym: BAS1757

Alternate gene names: 49184769

Gene position: 1780263-1780658 (Clockwise)

Preceding gene: 49184768

Following gene: 49184770

Centisome position: 34.05

GC content: 35.61

Gene sequence:

>396_bases
ATGGATAAGAAAAAATATATTGAAGAAGCAAATAAGATGTTGTCGAAAGCATATATTCCGTATTCAAAATTTCCTGTTGG
GGCAGCATTAGTTACGAAAGAAGGTAAAATCTATACTGGTTGTAATATAGAAAATGCTTCTTACGGTTTATGTAACTGTG
CAGAAAGAACAGCAATCTTTAAAGCAGTATCAGAAGGTGAGCGCGACTTTAGTTACTTAGTTATTACAGGAGAAACGGAC
GGACCAATTTCACCATGTGGTGCTTGTAGACAAGTAATTGCTGAATTCTGTGATCCGAAAATGCCTGTATTACTAACGAA
TGTAAAAGGCGATGAAAAAGAAGTGACTGTTGAGCAGTTACTGCCAGGTGCTTTTACAAATGACGATTTAAAATAA

Upstream 100 bases:

>100_bases
TGAGAACATTTCTATCGCTGAAACAGCAGTGGCTCCTAAATTAGTTCATACAGTTATTACTGACTAATTATAATTACACT
TACTTTGAGGGGGAAATAAT

Downstream 100 bases:

>100_bases
GTTAAAAGCCATTTTGCGATTAGTAATTGTAAAATGGCTTTTTGTTTGGAACATACAATGTAATATTTACTTTAGTTGGG
CTATTGGTTGTACGAGTAGC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MDKKKYIEEANKMLSKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIFKAVSEGERDFSYLVITGETD
GPISPCGACRQVIAEFCDPKMPVLLTNVKGDEKEVTVEQLLPGAFTNDDLK

Sequences:

>Translated_131_residues
MDKKKYIEEANKMLSKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIFKAVSEGERDFSYLVITGETD
GPISPCGACRQVIAEFCDPKMPVLLTNVKGDEKEVTVEQLLPGAFTNDDLK
>Mature_131_residues
MDKKKYIEEANKMLSKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIFKAVSEGERDFSYLVITGETD
GPISPCGACRQVIAEFCDPKMPVLLTNVKGDEKEVTVEQLLPGAFTNDDLK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=125, Percent_Identity=55.2, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=45.6692913385827, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551074, Length=125, Percent_Identity=47.2, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323274, Length=118, Percent_Identity=42.3728813559322, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=46.09375, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24582744, Length=141, Percent_Identity=40.4255319148936, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920920, Length=106, Percent_Identity=45.2830188679245, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14356; Mature: 14356

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKKYIEEANKMLSKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIF
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
KAVSEGERDFSYLVITGETDGPISPCGACRQVIAEFCDPKMPVLLTNVKGDEKEVTVEQL
HHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHH
LPGAFTNDDLK
CCCCCCCCCCC
>Mature Secondary Structure
MDKKKYIEEANKMLSKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIF
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
KAVSEGERDFSYLVITGETDGPISPCGACRQVIAEFCDPKMPVLLTNVKGDEKEVTVEQL
HHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHH
LPGAFTNDDLK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]