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The map label for this gene is ycbL [H]

Identifier: 49184751

GI number: 49184751

Start: 1759522

End: 1760220

Strand: Direct

Name: ycbL [H]

Synonym: BAS1739

Alternate gene names: 49184751

Gene position: 1759522-1760220 (Clockwise)

Preceding gene: 49184749

Following gene: 49184752

Centisome position: 33.65

GC content: 30.9

Gene sequence:

>699_bases
ATGGAGAAAAATTCAATTTTAATTGTAGATGATGATCAAGATATCGTTCGATTTATGAACGTGAATTTAATGCAAGAAGG
TTTTAAAGTTTTTAGTGCTTATAACGGAGAAGAGGCTTTAGAAATTATAAATAATAATAGCATTCAACTTGCTATTTTGG
ATATTATGATGCCACAAATGGATGGGATAGAATTGTGTAGACGGATTAGAGAGAAACATAGTTTACCAATTATATTTTTA
AGCGCCAAATCATCGGATGTAGATAAAGTTGTTGGATTTAGTACGGGAGCAGATGATTATATTGTGAAGCCGTTCAGTAC
AATTGAATTTATCGCAAGAGTGAAAGCACAATTAAGAAGGTATACATATTTCAATCAAAATGCTGTCCAAGTAATAGAAA
AGAAAATAAACATTAGAGGTTTAGAAATAGATGAAGTGTCGAGAACAGTAATGTTATATGGAGAAACAATCAATCTTACA
AAAACGGAATATGAAATTTTGTACTTAATGGCAGCTGCAAAAAATCGTGTGTTTACTATTGAAGAAATATATGAGAGCGT
TTGGAAAGAAAGGGCCTATGAAAGCAATAATACAGTAATGGTTCATATCGCAAGATTAAGAAATAAAATTGAAGAGGATC
CAAAAGAACCGAAGTTTATTCAAAATGTTTGGGGAGTCGGATATAAAATTGAAGATTAA

Upstream 100 bases:

>100_bases
ATATAATTTAGTCTGAAAATAAAGATTATTCAAGAGGGAAGTATGGCTTTAATTTATGATAAAATTGATTGTGGAATATA
TTTCAAAAAGAGGTTTGTAT

Downstream 100 bases:

>100_bases
AACATTACAAGGCATTAGAGCTAAGTTTTTTATCGCATTCTTATGTAGTATCTTGTTAGCAACTATAAGTATAATAGTGT
TTCAAATTTTAATTGGAAAT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEKNSILIVDDDQDIVRFMNVNLMQEGFKVFSAYNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIIFL
SAKSSDVDKVVGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAVQVIEKKINIRGLEIDEVSRTVMLYGETINLT
KTEYEILYLMAAAKNRVFTIEEIYESVWKERAYESNNTVMVHIARLRNKIEEDPKEPKFIQNVWGVGYKIED

Sequences:

>Translated_232_residues
MEKNSILIVDDDQDIVRFMNVNLMQEGFKVFSAYNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIIFL
SAKSSDVDKVVGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAVQVIEKKINIRGLEIDEVSRTVMLYGETINLT
KTEYEILYLMAAAKNRVFTIEEIYESVWKERAYESNNTVMVHIARLRNKIEEDPKEPKFIQNVWGVGYKIED
>Mature_232_residues
MEKNSILIVDDDQDIVRFMNVNLMQEGFKVFSAYNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIIFL
SAKSSDVDKVVGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAVQVIEKKINIRGLEIDEVSRTVMLYGETINLT
KTEYEILYLMAAAKNRVFTIEEIYESVWKERAYESNNTVMVHIARLRNKIEEDPKEPKFIQNVWGVGYKIED

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=34.6320346320346, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=31.4159292035398, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=34.375, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.0396475770925, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=32.1739130434783, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.6828193832599, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=31.6017316017316, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=32.3008849557522, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.4801762114537, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.7872340425532, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.4159292035398, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.4561403508772, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=30.8056872037915, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=28.1385281385281, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=123, Percent_Identity=34.1463414634146, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=33, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=33.6633663366337, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26964; Mature: 26964

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNSILIVDDDQDIVRFMNVNLMQEGFKVFSAYNGEEALEIINNNSIQLAILDIMMPQM
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCC
DGIELCRRIREKHSLPIIFLSAKSSDVDKVVGFSTGADDYIVKPFSTIEFIARVKAQLRR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
YTYFNQNAVQVIEKKINIRGLEIDEVSRTVMLYGETINLTKTEYEILYLMAAAKNRVFTI
HHHCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECEEECCCHHHHEEEEEEHHCCCEEEH
EEIYESVWKERAYESNNTVMVHIARLRNKIEEDPKEPKFIQNVWGVGYKIED
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHCCCEEECC
>Mature Secondary Structure
MEKNSILIVDDDQDIVRFMNVNLMQEGFKVFSAYNGEEALEIINNNSIQLAILDIMMPQM
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCC
DGIELCRRIREKHSLPIIFLSAKSSDVDKVVGFSTGADDYIVKPFSTIEFIARVKAQLRR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
YTYFNQNAVQVIEKKINIRGLEIDEVSRTVMLYGETINLTKTEYEILYLMAAAKNRVFTI
HHHCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECEEECCCHHHHEEEEEEHHCCCEEEH
EEIYESVWKERAYESNNTVMVHIARLRNKIEEDPKEPKFIQNVWGVGYKIED
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]