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The map label for this gene is dppE [H]

Identifier: 49184709

GI number: 49184709

Start: 1714076

End: 1715287

Strand: Reverse

Name: dppE [H]

Synonym: BAS1695

Alternate gene names: 49184709

Gene position: 1715287-1714076 (Counterclockwise)

Preceding gene: 49184714

Following gene: 49184708

Centisome position: 32.81

GC content: 33.66

Gene sequence:

>1212_bases
ATGAAGAAAAAGACGCAAGGAATCGTTGCACTCTCAATCACATTATCTATGTTTTTAACAGCATGTGGTCAAAAACAAGA
GGCAACAACTACCGGAGAAACGAAAAAAGAATCTTCAAAACAAGTATTAAACATTGTAGAAGCTGGGGAAATTTCTACAC
TTGATTCATCTATCGCAACCGATGGGTTTTCTTACGCTGCATTAAACAACATAATGGAAGGATTATATATGCCTGGTCCT
GACAATAAACCTGTTCCTGCAGCTGCTGAATCATACAAACTGAGCGAAGACGGAAAAACATATACATTTACATTACACGA
TTCAAAATGGTCAAATGGCGATCCAGTAACTGCTCATGATTTTGAATATGCATGGAAACGTGCCGTAAATCCAGAAACTG
CTTCTGAATACGCACATATTATGTTCGATATTAAAAACGCAGAAAAAATAAATAAAAAAGAATTGCCAATTGACTCATTT
GGTGTAAAAGCAATTGACGATAAAACATTAGAAGTACAGTTAGAACACCCTGTTCCATACTTTTTAGGTTTAATGGGATT
TGCAACATTTTATCCTCAAAACAAAAAAGTTGTAGACGCACAAGGGAAAAATTACGGACTTGAAGCTGCAAATGTAGTTT
ATAACGGACCTTTCCAATTAAGTGAATGGAAACATGATACAAGTTACAAAATGACGAAAAACCCGAACTACTGGGATAAT
AAAAATGTGAAATTAAATGAAATTAATGTAAATATCGTAAAAGATACTTCAACAGCTGTTAATTTATTTGAAAGTAAACA
AGTAGACCGAATTACGATTAATTCAGAGTTTGTTGATAAATATCAAAAAGATCCGAGCTTAAAGAAGATGGAACGTCCTT
CTGTGACGTTTTTCCGATTTAGTCAAAAGAACCCTTTATTAGCAAACAAAAATGCTCGTAAAGCTATTTCGCTTGCTTTT
GATAAACAAGGAATCGCAACAACGATTTTAAACAATGGTTCTATACCTGCGAATGCATTCGTTCCAAAAGGATTCGTAAA
AGGACCTGACAATAAAGATTTTCGCAGTACAAGTCATGTAAAAGTAGAAACAAATGTGAAAGAAGCTAAAACACTATGGG
AAACTGCGAAAAAAGAAACAAACTTACAAAACACTTCTCTTTCAATCATAACAACAGATGAGTCTAACGATAAAAAATTA
GTGAGTTTTTAA

Upstream 100 bases:

>100_bases
CATAAGATATTTTTTTCTATACGCTTTGTCGGATTTATTTATAGAAATTTTCTATATTTTCTTTTATACTAAGGCAGAGA
TGAAGGGAAGGATGACAACT

Downstream 100 bases:

>100_bases
AAGGTGAACTGGAGAAAAACTTACCTGGATTAAAAATCACATTACAACCACTTCCAGTAAAAGCATTTTTAGATCGTGAA
GGAAATGGCGATTTTGAAAT

Product: ABC transporter solute binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKKKTQGIVALSITLSMFLTACGQKQEATTTGETKKESSKQVLNIVEAGEISTLDSSIATDGFSYAALNNIMEGLYMPGP
DNKPVPAAAESYKLSEDGKTYTFTLHDSKWSNGDPVTAHDFEYAWKRAVNPETASEYAHIMFDIKNAEKINKKELPIDSF
GVKAIDDKTLEVQLEHPVPYFLGLMGFATFYPQNKKVVDAQGKNYGLEAANVVYNGPFQLSEWKHDTSYKMTKNPNYWDN
KNVKLNEINVNIVKDTSTAVNLFESKQVDRITINSEFVDKYQKDPSLKKMERPSVTFFRFSQKNPLLANKNARKAISLAF
DKQGIATTILNNGSIPANAFVPKGFVKGPDNKDFRSTSHVKVETNVKEAKTLWETAKKETNLQNTSLSIITTDESNDKKL
VSF

Sequences:

>Translated_403_residues
MKKKTQGIVALSITLSMFLTACGQKQEATTTGETKKESSKQVLNIVEAGEISTLDSSIATDGFSYAALNNIMEGLYMPGP
DNKPVPAAAESYKLSEDGKTYTFTLHDSKWSNGDPVTAHDFEYAWKRAVNPETASEYAHIMFDIKNAEKINKKELPIDSF
GVKAIDDKTLEVQLEHPVPYFLGLMGFATFYPQNKKVVDAQGKNYGLEAANVVYNGPFQLSEWKHDTSYKMTKNPNYWDN
KNVKLNEINVNIVKDTSTAVNLFESKQVDRITINSEFVDKYQKDPSLKKMERPSVTFFRFSQKNPLLANKNARKAISLAF
DKQGIATTILNNGSIPANAFVPKGFVKGPDNKDFRSTSHVKVETNVKEAKTLWETAKKETNLQNTSLSIITTDESNDKKL
VSF
>Mature_403_residues
MKKKTQGIVALSITLSMFLTACGQKQEATTTGETKKESSKQVLNIVEAGEISTLDSSIATDGFSYAALNNIMEGLYMPGP
DNKPVPAAAESYKLSEDGKTYTFTLHDSKWSNGDPVTAHDFEYAWKRAVNPETASEYAHIMFDIKNAEKINKKELPIDSF
GVKAIDDKTLEVQLEHPVPYFLGLMGFATFYPQNKKVVDAQGKNYGLEAANVVYNGPFQLSEWKHDTSYKMTKNPNYWDN
KNVKLNEINVNIVKDTSTAVNLFESKQVDRITINSEFVDKYQKDPSLKKMERPSVTFFRFSQKNPLLANKNARKAISLAF
DKQGIATTILNNGSIPANAFVPKGFVKGPDNKDFRSTSHVKVETNVKEAKTLWETAKKETNLQNTSLSIITTDESNDKKL
VSF

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=320, Percent_Identity=31.5625, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789397, Length=336, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87081878, Length=394, Percent_Identity=28.6802030456853, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787052, Length=386, Percent_Identity=24.0932642487047, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789966, Length=273, Percent_Identity=26.3736263736264, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789887, Length=230, Percent_Identity=29.1304347826087, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787762, Length=263, Percent_Identity=24.7148288973384, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 45036; Mature: 45036

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTQGIVALSITLSMFLTACGQKQEATTTGETKKESSKQVLNIVEAGEISTLDSSIAT
CCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHC
DGFSYAALNNIMEGLYMPGPDNKPVPAAAESYKLSEDGKTYTFTLHDSKWSNGDPVTAHD
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCEEECCCCCEEEEEEECCCCCCCCCCEECC
FEYAWKRAVNPETASEYAHIMFDIKNAEKINKKELPIDSFGVKAIDDKTLEVQLEHPVPY
HHHHHHHCCCCCHHHCEEEEEEEECCCHHCCHHCCCCCCCCCEEECCCEEEEEECCCCHH
FLGLMGFATFYPQNKKVVDAQGKNYGLEAANVVYNGPFQLSEWKHDTSYKMTKNPNYWDN
HHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCEECCCCCCCCCEEECCCCCCCCC
KNVKLNEINVNIVKDTSTAVNLFESKQVDRITINSEFVDKYQKDPSLKKMERPSVTFFRF
CCEEEEEEEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHCCCCEEEEEE
SQKNPLLANKNARKAISLAFDKQGIATTILNNGSIPANAFVPKGFVKGPDNKDFRSTSHV
CCCCCCEECCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
KVETNVKEAKTLWETAKKETNLQNTSLSIITTDESNDKKLVSF
EEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCC
>Mature Secondary Structure
MKKKTQGIVALSITLSMFLTACGQKQEATTTGETKKESSKQVLNIVEAGEISTLDSSIAT
CCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHC
DGFSYAALNNIMEGLYMPGPDNKPVPAAAESYKLSEDGKTYTFTLHDSKWSNGDPVTAHD
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCEEECCCCCEEEEEEECCCCCCCCCCEECC
FEYAWKRAVNPETASEYAHIMFDIKNAEKINKKELPIDSFGVKAIDDKTLEVQLEHPVPY
HHHHHHHCCCCCHHHCEEEEEEEECCCHHCCHHCCCCCCCCCEEECCCEEEEEECCCCHH
FLGLMGFATFYPQNKKVVDAQGKNYGLEAANVVYNGPFQLSEWKHDTSYKMTKNPNYWDN
HHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCEECCCCCCCCCEEECCCCCCCCC
KNVKLNEINVNIVKDTSTAVNLFESKQVDRITINSEFVDKYQKDPSLKKMERPSVTFFRF
CCEEEEEEEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHCCCCEEEEEE
SQKNPLLANKNARKAISLAFDKQGIATTILNNGSIPANAFVPKGFVKGPDNKDFRSTSHV
CCCCCCEECCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
KVETNVKEAKTLWETAKKETNLQNTSLSIITTDESNDKKLVSF
EEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]