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The map label for this gene is dsdA

Identifier: 49184667

GI number: 49184667

Start: 1667870

End: 1669210

Strand: Direct

Name: dsdA

Synonym: BAS1653

Alternate gene names: 49184667

Gene position: 1667870-1669210 (Clockwise)

Preceding gene: 49184666

Following gene: 49184668

Centisome position: 31.9

GC content: 36.76

Gene sequence:

>1341_bases
ATGAAGGAAATAGAGAAATTAAAAGAGGAATATCCACTATTAAATAAATTGATTGAAATAGAAGAAGTGTTTTGGGTGAA
TCCGAACATGGAAAAGTATGAAACGGCAATAAAAGATTCGCCACTCAGTGAAGAGAATGTAAAAGATGCGGAGGAGAGGT
TAAAGCGTTTTGCATCATACATTGCGAAAGTTTTTCCTGAAACGAAAGACACAGGCGGTATTATAGAATCACCTTTAGTG
AAGATACCTTCTATGAAACAGTCTTTAGAGAAAAATTACGAGCAACCTATATTAGGAGAATTATTATTAAAATGTGATAG
TCATCTCCCGATATCAGGATCAATTAAAGCTAGAGGCGGCATTTATGAAGTGTTGAAACATGCTGAACAATTAGCTTTGC
AGCAAGGTATGTTAACAGAAGAAGATGATTATTCCATTTTAGATAGTGATACATGTAGAGAGTTTTTTGCCACTTATTCC
ATCGCGGTAGGTTCGACAGGGAATTTAGGATTAAGTATTGGGATTATGAGTGCGAAGTTAGGTTTTAACGTAACGGTTCA
TATGTCAGCAGACGCGAAACAATGGAAAAAAGATTTATTAAGAAGTAAAGGTGTAAATGTTATTGAATATGAAGCTGATT
ATAGTAAAGCTGTAGAAGAAGGAAGAAGGCAAGCAGATGCTGATCCTAGCTGTTATTTTGTAGATGATGAAAACTCACAT
GATTTATTTTTAGGATACGCAGTAGCGGCATCGCGTTTACAAAAACAATTAGAAGAGTTAGAGATTATAGTGGATGAAGA
GCATCCTTTATTCGTTTATCTGCCATGCGGAGTAGGTGGCGGACCTGGCGGAGTCGCATTTGGTTTAAAGTTATTGTATA
AAGACAACGTACACTGTTTCTTTGCAGAGCCAACACATTCTCCATGTATGTTAATCGGGTTAATGACAGGACTTCATGAT
AAAATCGCCGTTCAAGATATCGGAATTGATAATGTAACAGACGCAGACGGACTTGCGGTAGGAAGGCCATCTGGATTTGT
TGGTAAAACGATGGAACCATTTTTGAGCGGGAATTACACAGTAAGTGATGAAGAATTGTATAGGTTGTTAAAAGAGCTAG
CTGATACGGAAAATATTTATTTAGAGCCTTCTGCATTAGCAGGTATGATAGGACCAGTAAAAGTATGTAAAGAAGATGCG
TATTTACAAGAGCAACAGTTAATGGAGAAGATGAAAAAAGGTACTCATATTGTATGGGGAACGGGCGGTAGTATGGTTCC
AGAAGATGTGATGAATGGGTATTATAAAACAGGTGAGGCATTAACAATATTAGAAAAATGA

Upstream 100 bases:

>100_bases
CGGACAGGAAAAAGGTGAGATTCCTTTTCGGTAGTTGGCATTTGACTTGGTTCGCCAACAATTTATAGATTTTTATAAGA
ATTTTAAACCAGGAAGAGGA

Downstream 100 bases:

>100_bases
GGCTAGATGTAGCCTCATTTTTTCATGTACATAAAAATCTTTGTTATTTTCACAATAGTTCTTTATAGTATAGATAAAGG
ATAACTAATATTGAATAAAT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLV
KIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYS
IAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDA
YLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK

Sequences:

>Translated_446_residues
MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLV
KIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYS
IAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDA
YLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
>Mature_446_residues
MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLV
KIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYS
IAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDA
YLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=438, Percent_Identity=62.5570776255708, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_BACAC (C3L7G5)

Other databases:

- EMBL:   CP001215
- RefSeq:   YP_002815402.1
- ProteinModelPortal:   C3L7G5
- EnsemblBacteria:   EBBACT00000123149
- GeneID:   7783643
- GenomeReviews:   CP001215_GR
- KEGG:   bah:BAMEG_2806
- GeneTree:   EBGT00050000001628
- ProtClustDB:   PRK02991
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 49496; Mature: 49496

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASY
CCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IAKVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGG
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
IYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEEEEEEC
GFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSH
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCC
DLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCF
EEEHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCHHHHHHHHEEECCEEEE
FAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYT
EECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHCCCCE
VSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWG
ECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGGSMVPEDVMNGYYKTGEALTILEK
CCCCCCCHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure
MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASY
CCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IAKVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGG
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
IYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEEEEEEC
GFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSH
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCC
DLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCF
EEEHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCHHHHHHHHEEECCEEEE
FAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYT
EECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHCCCCE
VSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWG
ECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGGSMVPEDVMNGYYKTGEALTILEK
CCCCCCCHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA