| Definition | Bacillus anthracis str. Sterne chromosome, complete genome. |
|---|---|
| Accession | NC_005945 |
| Length | 5,228,663 |
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The map label for this gene is mprF [H]
Identifier: 49184392
GI number: 49184392
Start: 1405722
End: 1408307
Strand: Reverse
Name: mprF [H]
Synonym: BAS1375
Alternate gene names: 49184392
Gene position: 1408307-1405722 (Counterclockwise)
Preceding gene: 49184407
Following gene: 49184389
Centisome position: 26.93
GC content: 36.04
Gene sequence:
>2586_bases ATGTCGTTTTCATGGAAACGTTTCTTACAAATCGGGAAAATTATCTTCCCATTTGTTGTATTAACAATTGTATTCTTTCA AGCAAAAAAAGAATTAGCAGGCATTTCTTTTTTAGAAGCAATCAATACAATTAAAAACATTCCAACCGGAGGAGTCTTTT TAGCAATTACACTTGGTGCATTTGCCGTATCCACAATGTTCTTTTATGACTATGTTATGCTTCGTTATTTAAAAGCTGAT ATACCAGTCCAAAAGATTTTTCGTATCTCATGGATTGCTAATACCTTAAATGGATTTATTGGATTTGGTGGTCTCGTTGG AGCAGGTGTACGCACAATGCTGTATCGTCCATACATAAAAGAAAATGGCAAACTTATTAAAAGTATCGCTTGGATGACAA CCGCTTTTATTAACGGACTAGCTATTCTTTCGTTCCTCGGTCTTATCGGAATATTAGACACAAGTTTTATTTTGCATGAA AAACCGTGGCTATGGCCTGTTCTTATCTTCTTCGCTCTTTTCGTCCCTATATACATTGGCTTCTCTAAACTAAAAAATAG AAAAACGAAGCAAGCGGAAGGACAAGATGAAGGAGAAGAAGAGAAAAATCCAACTGTTTTATACTCATTAGTTTCATTAG TTGAGTGGGTATCTGCTGGTATTGTTATGTACGTCATATTAATATTATTTGGGATCGATATCGAATTTCAAAAGTTTTTA GGTGTGTATGTAATTGCTGCTTTAGCTGGCGTTGTTAGTCTTGTTCCTGGTGGACTGGGTTCATTTGATCTTGTCTTTTT AACTGGACTTGGACAATACGGCATTGATACAGGCGTATTACTACCTGCTATGTTATTATATCGCCTTGTCTATTACATTT TACCGTTCTGCCTTGGTCTTATTTTTGCAGCTTTTGAAATGACAGGTGTGGCCATTAAAAAGTTTGAAGATAAGCCTTTT ATTGCGCCTGCATTAGAAACAACTGGTGTTATATGGACTTTGCAGCGTGATTTTCTAGGAAAACTAGGTTCATGGGCCTC TGCTGCTTTAACAGTATTTGCTGGACTAATGGTTATTTTATCGACCATTCTACCAACAAGTATAAACAGAGCACACGCCT TACATATTCTAGCTCCAAAACATCTTATTCAATTTTCTTTTAGCTTATCACTAACATTTGGTATTCTCCTCCTGATCCTT TCACGAGGCATATATTATGGAACAAAGCGTTCTTACTATATGACGATTATTTCTTTAATCGGAGCAGCCGTCTTTAATAC GCTAAAAGGGATTGATATTGAAGAAACGTTTATTTTATTAATCGTACTCGCTGTATTATATATGCTTCGTAAAAGATTTG TACGCGAGAAAATGGAAGTCTCACTTTCTGATATCGTAAAAGTTTTTATATTCTTACTTATAACTTTATATTTATATAAA AACTTAGGTATTTTATTTGCAGGTGCAAAAGAAGCTTTTAAACCTGATTTTGTCGTTCGTAATATTACGCAAGTGAAACG AAGTGCATTAGCTGCTGCCTTTTTCGTTCCTACATTTTTACTGATTGGCTCACTCATTGCTAATCGTTATCGAAATGAAT TTCCCGGGCAACCAGCTAATGATAAAAGATTGCAAAACTTTTTAGATGAACATGGCGGAAATGTACTTAGTCATTTAGGA TTTTTAGGTGATAAACAATTCTTCTTCAGTAGCGATGGGAAAGCGCTCCTTCTCTTCTCTATAACTGGAAAACGTCTTGT TGTGCTAGGTGATCCAATTGGAGATCCTTCCTCCTACCGTACTGTGTTACAGGAGTTTTTAGCTGAGGCTGATCGATTTG GATACATTTGTGTATTCTACCAAATCGAAAGTAAATGGATGAGTTTATATCATGATTTCGGTTACAACTTCTTTAAGCTT GGTGAAGAAGCTGTCGTTGATTTGAACACATTTACAATAACAGGAAAAAAACGCGCCGGTATGCGAGCAACTTTCAACCG TTTTGAACGAGAGGGCTATACATTCTCTATTCACCAGCCACCGTTCTCAAACGAATTATTTGAAGAATTACGAAAAGTTT CAGATGCGTGGCTCGGTGGAAAAAAAGAGAAAAGTTTCTCACTCGGATACTTTGATCATGAATATATTAACCGAGCACCT ATCGCTACATTATCTGATGCAGATGGAAAAATCATCGCATTTACAACTTTTATGCCAGTATATCAAGACGGATCATTGTC TGTTGATTTAATGCGGTATTATCCAGATGCACCTAGCGGCATTATGGATGCCATTTTCATCCACCTATTCCAGTGGGCAA AAGAAAATGAATACCACTCCTTTAATATTGGCATGGCGCCACTTTCAAATGTAGGTTTATCGACACAATCTTTCTGGTCT GAACGAGTTGCCGCTGCCATCTTTAATAATGTTCGTTATACATATAGTTTCAGCGGGTTACGACATTTTAAAGAAAAATA TAAACCAGCATGGAGCGGTAAATATTTAGCATTTAGAAAGAATCATTCTTTACCAATTACAATGCTCTCTGTAACAAAAT TAATAGGAAAAAGAAAAAACAGCTAA
Upstream 100 bases:
>100_bases AAATAGCTTCCTTATACAGGAATTTACCTTTTTATTTTTCTTGAAGTTTGTCATAATAATATTATTGTCTCAGTTTTCTT ATACAAGGAGAGTTGTATTT
Downstream 100 bases:
>100_bases ATAGTTAGCTGTTTTTTCTTTTTTGAACTTGTACAATGAATTCTTTTTCATATTTCTTTCCATTTATATAGAAATCTCCC CATATTTTATACGTTCCTTC
Product: virulence factor MprF
Products: NA
Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]
Number of amino acids: Translated: 861; Mature: 860
Protein sequence:
>861_residues MSFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAINTIKNIPTGGVFLAITLGAFAVSTMFFYDYVMLRYLKAD IPVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIKENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTSFILHE KPWLWPVLIFFALFVPIYIGFSKLKNRKTKQAEGQDEGEEEKNPTVLYSLVSLVEWVSAGIVMYVILILFGIDIEFQKFL GVYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGLIFAAFEMTGVAIKKFEDKPF IAPALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVILSTILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLIL SRGIYYGTKRSYYMTIISLIGAAVFNTLKGIDIEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLITLYLYK NLGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPANDKRLQNFLDEHGGNVLSHLG FLGDKQFFFSSDGKALLLFSITGKRLVVLGDPIGDPSSYRTVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKL GEEAVVDLNTFTITGKKRAGMRATFNRFEREGYTFSIHQPPFSNELFEELRKVSDAWLGGKKEKSFSLGYFDHEYINRAP IATLSDADGKIIAFTTFMPVYQDGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHSFNIGMAPLSNVGLSTQSFWS ERVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRKNHSLPITMLSVTKLIGKRKNS
Sequences:
>Translated_861_residues MSFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAINTIKNIPTGGVFLAITLGAFAVSTMFFYDYVMLRYLKAD IPVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIKENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTSFILHE KPWLWPVLIFFALFVPIYIGFSKLKNRKTKQAEGQDEGEEEKNPTVLYSLVSLVEWVSAGIVMYVILILFGIDIEFQKFL GVYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGLIFAAFEMTGVAIKKFEDKPF IAPALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVILSTILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLIL SRGIYYGTKRSYYMTIISLIGAAVFNTLKGIDIEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLITLYLYK NLGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPANDKRLQNFLDEHGGNVLSHLG FLGDKQFFFSSDGKALLLFSITGKRLVVLGDPIGDPSSYRTVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKL GEEAVVDLNTFTITGKKRAGMRATFNRFEREGYTFSIHQPPFSNELFEELRKVSDAWLGGKKEKSFSLGYFDHEYINRAP IATLSDADGKIIAFTTFMPVYQDGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHSFNIGMAPLSNVGLSTQSFWS ERVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRKNHSLPITMLSVTKLIGKRKNS >Mature_860_residues SFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAINTIKNIPTGGVFLAITLGAFAVSTMFFYDYVMLRYLKADI PVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIKENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTSFILHEK PWLWPVLIFFALFVPIYIGFSKLKNRKTKQAEGQDEGEEEKNPTVLYSLVSLVEWVSAGIVMYVILILFGIDIEFQKFLG VYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGLIFAAFEMTGVAIKKFEDKPFI APALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVILSTILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLILS RGIYYGTKRSYYMTIISLIGAAVFNTLKGIDIEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLITLYLYKN LGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPANDKRLQNFLDEHGGNVLSHLGF LGDKQFFFSSDGKALLLFSITGKRLVVLGDPIGDPSSYRTVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKLG EEAVVDLNTFTITGKKRAGMRATFNRFEREGYTFSIHQPPFSNELFEELRKVSDAWLGGKKEKSFSLGYFDHEYINRAPI ATLSDADGKIIAFTTFMPVYQDGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHSFNIGMAPLSNVGLSTQSFWSE RVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRKNHSLPITMLSVTKLIGKRKNS
Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu
COG id: COG2898
COG function: function code S; Uncharacterized conserved protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the LPG synthase family [H]
Homologues:
None
Paralogues:
None
Copy number: 10-20 Molecules/Cell [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016181 - InterPro: IPR022791 [H]
Pfam domain/function: PF03706 UPF0104 [H]
EC number: =2.3.2.3 [H]
Molecular weight: Translated: 97014; Mature: 96883
Theoretical pI: Translated: 9.83; Mature: 9.83
Prosite motif: PS01039 SBP_BACTERIAL_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAINTIKNIPTGGVFLAITLGA CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH FAVSTMFFYDYVMLRYLKADIPVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIK HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH ENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTSFILHEKPWLWPVLIFFALFVPIYIG CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH FSKLKNRKTKQAEGQDEGEEEKNPTVLYSLVSLVEWVSAGIVMYVILILFGIDIEFQKFL HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH GVYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGL HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH IFAAFEMTGVAIKKFEDKPFIAPALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVIL HHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHH STILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLILSRGIYYGTKRSYYMTIISLI HHHHCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHH GAAVFNTLKGIDIEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLITLYLYK HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH NLGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPAN CCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC DKRLQNFLDEHGGNVLSHLGFLGDKQFFFSSDGKALLLFSITGKRLVVLGDPIGDPSSYR HHHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCEEEEEEECCCEEEEEECCCCCCHHHH TVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKLGEEAVVDLNTFTITGKKRAG HHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHCCHHHHCCCHHEEEEEEEEEECCCCCC MRATFNRFEREGYTFSIHQPPFSNELFEELRKVSDAWLGGKKEKSFSLGYFDHEYINRAP HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC IATLSDADGKIIAFTTFMPVYQDGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHS CCEECCCCCCEEEEEEECCEECCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCE FNIGMAPLSNVGLSTQSFWSERVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRK EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEC NHSLPITMLSVTKLIGKRKNS CCCCCCHHHHHHHHHHCCCCC >Mature Secondary Structure SFSWKRFLQIGKIIFPFVVLTIVFFQAKKELAGISFLEAINTIKNIPTGGVFLAITLGA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH FAVSTMFFYDYVMLRYLKADIPVQKIFRISWIANTLNGFIGFGGLVGAGVRTMLYRPYIK HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH ENGKLIKSIAWMTTAFINGLAILSFLGLIGILDTSFILHEKPWLWPVLIFFALFVPIYIG CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH FSKLKNRKTKQAEGQDEGEEEKNPTVLYSLVSLVEWVSAGIVMYVILILFGIDIEFQKFL HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH GVYVIAALAGVVSLVPGGLGSFDLVFLTGLGQYGIDTGVLLPAMLLYRLVYYILPFCLGL HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH IFAAFEMTGVAIKKFEDKPFIAPALETTGVIWTLQRDFLGKLGSWASAALTVFAGLMVIL HHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHH STILPTSINRAHALHILAPKHLIQFSFSLSLTFGILLLILSRGIYYGTKRSYYMTIISLI HHHHCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHH GAAVFNTLKGIDIEETFILLIVLAVLYMLRKRFVREKMEVSLSDIVKVFIFLLITLYLYK HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH NLGILFAGAKEAFKPDFVVRNITQVKRSALAAAFFVPTFLLIGSLIANRYRNEFPGQPAN CCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC DKRLQNFLDEHGGNVLSHLGFLGDKQFFFSSDGKALLLFSITGKRLVVLGDPIGDPSSYR HHHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCEEEEEEECCCEEEEEECCCCCCHHHH TVLQEFLAEADRFGYICVFYQIESKWMSLYHDFGYNFFKLGEEAVVDLNTFTITGKKRAG HHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHCCHHHHCCCHHEEEEEEEEEECCCCCC MRATFNRFEREGYTFSIHQPPFSNELFEELRKVSDAWLGGKKEKSFSLGYFDHEYINRAP HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC IATLSDADGKIIAFTTFMPVYQDGSLSVDLMRYYPDAPSGIMDAIFIHLFQWAKENEYHS CCEECCCCCCEEEEEEECCEECCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCE FNIGMAPLSNVGLSTQSFWSERVAAAIFNNVRYTYSFSGLRHFKEKYKPAWSGKYLAFRK EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEC NHSLPITMLSVTKLIGKRKNS CCCCCCHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8946165; 9384377 [H]