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The map label for this gene is atoS [H]

Identifier: 49184384

GI number: 49184384

Start: 1396766

End: 1397908

Strand: Reverse

Name: atoS [H]

Synonym: BAS1367

Alternate gene names: 49184384

Gene position: 1397908-1396766 (Counterclockwise)

Preceding gene: 49184386

Following gene: 49184383

Centisome position: 26.74

GC content: 30.53

Gene sequence:

>1143_bases
ATGCTTCCAAACGATGATATTATATCTCATGAAAAACGAATAGAAGAACTAGAGAATAAAGTGCGTTTTTATGAAGAACT
TGTAAATCAATTACCACATCATTTCACATATAAAAATCCACATATTGGTTTACAAATAAAGAAAACGAGATCGACTCATT
CCATTCAAAACATACAAAAAGAGAATAAAGAGGCTGACTTTCAACTTACTTGCGATTCATTATTTTTATTTAAACAACTT
GAAACATACTTTATTCATATTTTTGATGCTTTTTCACATCATGTAACCTTTGTTGATAATAAAGGAAATATAACTTTATG
TAATCAGGCTGCAGCAGATGATTTTGGTGTAGTACGAAATGATATAATTGGAAAACCAATTCAACAATTACTAAAATTGC
CTGAAGAAAAAATTAAAGCTCTAGAAACATTAAGAACAGGCACAGAAATATATAATGAAGAAGTCTTAGACAAAAACTAT
GGCATTTTAAATAACCGAATTATTCGTGATTATAACGGAGAGATTTTTAGGGTTATTAGTGTTTTTCATTATTTAAACAC
AGAACGTGATGCAGAAAAATTTTCGTTAGCAGGGCGAATCGCAGCTGGTATTGCACATGAAGTACGTAACCCTCTTACAA
CCGTACGAGGATATTTACAATTTTTACAAGAAAATGTTTCTCCATCTAATAAAGAACTATTTAAAAACTTACTTATTCCT
GAATTAGATCGCGCAAATAGTATCATTACAAAATTTTTATCTATTTCAAAAACACGCGAATTTACAAGAGAACCCTTTCC
CATTAATACATTTTTACGTGAGTATATTCAACAGTTACTAGCTAGTGAAGTCTTTTTACATAACATTTCAATTGATTATA
ATTTTTCTACTGAATTAGATGATATTTTAGTTCATATTGATCGCCATGAACTTGTACAAGTTTTTTTAAACTTATTCCAG
AACGCTGTCGATGCTCAAGGAGAAAAAAACTTTCTATACAAATCACTAGTTACCGCCTTGATAATTTTGTTCGTATTACT
TTCACTGATAATGGGACTGGTATTCCACCAGCGATTCAAGAATATATCTTTGATCCATTCTTCTCAACAAAAGATTCCGG
CACAGGTTTGGGCTTGTCAGTAA

Upstream 100 bases:

>100_bases
GACCAATCAATTTCATTAAGTAGTCCCATCTTTAAGAGTATTCATATAAAAATATGATATACTAGATGGAAGAATTTTTA
AATTGAGGGGTTATTTATTT

Downstream 100 bases:

>100_bases
CGAAAAAAATTATCCAAAATCATAATGGTACATTAAAAATGACTAGTAATGAAGATGGTACTACTTTTACTATTTCAATT
CCAATCTTACCTAAAACAGC

Product: histidine kinase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNKGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKNFLYKSLVTALIILFVLLSLIMGLVFHQRFKNISLIHSSQQKIPAQVWACQ

Sequences:

>Translated_380_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNKGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKNFLYKSLVTALIILFVLLSLIMGLVFHQRFKNISLIHSSQQKIPAQVWACQ
>Mature_380_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNKGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKNFLYKSLVTALIILFVLLSLIMGLVFHQRFKNISLIHSSQQKIPAQVWACQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=28.3464566929134, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1790436, Length=143, Percent_Identity=29.3706293706294, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44232; Mature: 44232

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHH
ENKEADFQLTCDSLFLFKQLETYFIHIFDAFSHHVTFVDNKGNITLCNQAAADDFGVVRN
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCHHHHHHH
DIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNYGILNNRIIRDYNGEIFRVIS
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELD
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHH
DILVHIDRHELVQVFLNLFQNAVDAQGEKNFLYKSLVTALIILFVLLSLIMGLVFHQRFK
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NISLIHSSQQKIPAQVWACQ
HHHHHHCCHHHCCCHHCCCC
>Mature Secondary Structure
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHH
ENKEADFQLTCDSLFLFKQLETYFIHIFDAFSHHVTFVDNKGNITLCNQAAADDFGVVRN
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCHHHHHHH
DIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNYGILNNRIIRDYNGEIFRVIS
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELD
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHH
DILVHIDRHELVQVFLNLFQNAVDAQGEKNFLYKSLVTALIILFVLLSLIMGLVFHQRFK
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NISLIHSSQQKIPAQVWACQ
HHHHHHCCHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]