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The map label for this gene is ydjE [H]

Identifier: 49183740

GI number: 49183740

Start: 774112

End: 775053

Strand: Reverse

Name: ydjE [H]

Synonym: BAS0716

Alternate gene names: 49183740

Gene position: 775053-774112 (Counterclockwise)

Preceding gene: 49183741

Following gene: 49183735

Centisome position: 14.82

GC content: 35.88

Gene sequence:

>942_bases
ATGAGAAATGTCTTTTGTATCGGTGAACTATTAATTGATTTCGTTTGCCGAAATACCAATGTTTCTTTAGTAAACGGTTC
AAATTTCGAAAAAAAGGCTGGTGGAGCACCTGCTAACGTTGCTGCTGCTATTACAAAATTAGGTGGACACGCTACATTTA
TGGGACAAGTAGGAAACGATCCATTTGGTGAATTTCTTGAACAAACTTTACAACATGCACATGTGGACACTTCCATGCTC
ATCAAGGATAAACAAACCACACTTGCATTCGTATCTATCGATCAAAATGGTGAGCGTGATTTCACCTTTATGCGTGGCGC
AGACGGTGAATATCATTTCAATAGCATTGATTTATCAAAAATAAAAACGAATGATTTAATCCATTTTGGTTCAGCGACAG
CTTTATTGTCCAGCCCGTTAAAAGACACATATTTTCAACTTCTACAACATGCAAGAGAAAGTGGCCAGTTTATTTCTTTT
GATCCAAATTACCGAAATGCGCTCATTACAAATACCGAACAATTTATTCAAGATTGCTTAACTTTTATAAAACATGCTCA
TTTTGTAAAAGTAAGTCAAGAAGAAGCGATTATGCTTTCTAAAGAGAGTGATTTACAACAATCTGCACTCAAATTATTAA
ATCATGGTGCGAAAGCCGTAGCTATTACACTCGGAAAAGACGGTACTCTTCTTGCAACAAAGGATAAGCAAACTATTGTA
CCTTCTATCTCTATTCAACAAGTTGATACTACTGGCGCTGGTGATGCTTTCGTTGGAGCAATGTTATACCAAATTGCTAA
AAGTGAACAAATGTTTCTTCATAATTTTGAAGGTTTAACAACGTTTATCTCCTTTGCAAATAAAGTAGGTGCTCTCACAT
GTACAAATTATGGAGCCATTTCCTCTCTTCCATCATTAACAGATGTAAAAGCATACGAGTAA

Upstream 100 bases:

>100_bases
GAGTCTTTCCTCGAAAAGACATGAAACATCATATCGCAATCTTTTCAGATGCAAAACTAAACTTTACCATCACACAATAT
AAGCTGAAAAGAGGGATTGT

Downstream 100 bases:

>100_bases
TCGTATGCTTTTACATTCCCCTCCAAAAATCATGCATAATAAAAAAGTACAAAATAACGAGAACTGCCGTCCCGCATAAG
GTAATACGCCGATATATACT

Product: fructokinase

Products: ADP; D-fructose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQHARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQMFLHNFEGLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE

Sequences:

>Translated_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQHARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQMFLHNFEGLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE
>Mature_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQHARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQMFLHNFEGLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=285, Percent_Identity=25.6140350877193, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87081971, Length=312, Percent_Identity=23.7179487179487, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082281, Length=280, Percent_Identity=23.9285714285714, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790193, Length=294, Percent_Identity=24.1496598639456, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=297, Percent_Identity=26.5993265993266, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20128807, Length=323, Percent_Identity=25.3869969040248, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.4

Molecular weight: Translated: 34192; Mature: 34192

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQHAHVDTSMLIKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSK
HHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECCEEHHH
IKTNDLIHFGSATALLSSPLKDTYFQLLQHARESGQFISFDPNYRNALITNTEQFIQDCL
CCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHH
TFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
HHHHHHHEEEECCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEC
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQMFLHNFEGLTTFISFANKVGALTCTNYGAI
CCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCH
SSLPSLTDVKAYE
HCCCCCCCCCCCC
>Mature Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQHAHVDTSMLIKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSK
HHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECCEEHHH
IKTNDLIHFGSATALLSSPLKDTYFQLLQHARESGQFISFDPNYRNALITNTEQFIQDCL
CCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHH
TFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
HHHHHHHEEEECCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEC
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQMFLHNFEGLTTFISFANKVGALTCTNYGAI
CCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCH
SSLPSLTDVKAYE
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-fructose

Specific reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]