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The map label for this gene is nagP [H]

Identifier: 49183500

GI number: 49183500

Start: 494259

End: 495752

Strand: Direct

Name: nagP [H]

Synonym: BAS0472

Alternate gene names: 49183500

Gene position: 494259-495752 (Clockwise)

Preceding gene: 304570533

Following gene: 49183501

Centisome position: 9.45

GC content: 38.42

Gene sequence:

>1494_bases
ATGTTGCAGTTTCTACAACGTATTGGTAAAGCGTTAATGCTTCCAATCGCCGTACTACCAGCAGCAGGATTATTGCTTCG
TTTAGGACAAGAAGACGTATTTAACATTCCTGTTATGGCACAGGCCGGTGCAGCAATTTTTGATAATTTAGCACTTATTT
TTGCAATTGGTGTTGCAATCGGTTTGTCTGTTGACGGTAGTGGAGCAGCTGGACTTGCCGGAGCAATCGGATATCTTGTT
TTACAAAATACAACGAATGCTCTAAGTAAGACGTATTCAGCAGCAGAGTTAAATGATAAATTAAAAAGTGTTCAAGATTT
AGTCGGTTCAGTAGATCCAACTAAATTAGCAGATACAATGACAAAGGTTTCAAAAGCAGCGGCGTTAACGCCAAAAATAA
ATATGGCCATACTCGGTGGTATTATTGCAGGGGTTGTTGCGGGATTACTATACAACAAATTCCATAAGATTAAACTACCA
GAATGGTTAGGATTCTTTGCAGGAAAACGCTTCGTACCAATCATTACTTCAATCGTAATGTTACTTTTAGGATTGGTATT
CGGTCAAATTTGGCCAACAATTCAAAGTGGTATTGATGCAGTGGCACATGGTATCGTGAACTTAGGTTCAATTGGTGCTG
GTTTATTTGGATTATTAAACCGTTTATTAATTCCAATTGGTTTACACCACGTAATGAACACATACTTCTGGTTCGTACTT
GGTGACTTTACAAATGCAGCTGGCGATATTGTTCATGGTGATATTGCACGTTTCTTTGCAAAAGATCCATCAGCAGGTAT
GTTTATGACTGGTTTCTTCCCAGTTATGATGTTCGGTTTACCAGCAGCATGTTTCGCAATGATTGCAGCTGCTAAACCAG
AAAAACGTAAAATGGTTACAGGTATGTTAGGTGGTCTAGCATTAACTTCATTCTTAACTGGTATTACAGAGCCAATTGAA
TTCTCATTCATGTTCTTATCGCCAGTACTATATGGAATTCATGCTGTATTAACAGGTCTATCTCTATTCATTACAACAAC
ACTTGGCATTCATGATGGTTTCTCATTTAGTGCCGGGGCAATCGATTACGTCTTAAACTTCGGTATTGCAACAAAACCAT
TGTTACTAGCAGGAATCGGTTTAATTTACGCAGCAATTTACTTTGTAGTATTCTACTTCTTAATTAAGAAGTTCGACCTA
AAAACTCCTGGTCGTGAAGATGAAGAGGAAATGGCTGAAGGCGAAGAAGCTCCAGTTGCAGGTTCAATTGGTGAAACTTA
CGTAGCAGCTTTAGGTGGAAAAGAAAACTTAACAGTTATTGATAACTGTGCAACACGTCTACGCTTACAAGTGAAAGATG
CTGGTCAAGTAAACGAAGCAGCATTAAAACGTGCTGGTGCAAAAGGTGTTATGAAATTAAGTAACACGAGTGTCCAAGTT
ATCGTAGGTACAAATGTTGAATCTGTTGCCGATGATATGAAAAAACACGTATAA

Upstream 100 bases:

>100_bases
CTATACAACTATATGTTATTATGGTTATGTAAATAGAAAGCGTTTTCTAAGGTGTACTTATAATGATAACGATTTCATAA
ATTTGATAGGGGGAATTAAA

Downstream 100 bases:

>100_bases
ATAATTAGATAAGAGGATATCCAAAAAGATTGATAACATCAATTTTTTAGAGGGTATCCTCTTTTTTTATGTTAAAAAAT
TAATGGGAATCTTACTTTTG

Product: PTS system N-acetylglucosamine-specific transporter subunit IIBC

Products: NA

Alternate protein names: EIICB-Nag; N-acetylglucosamine permease IIC component; PTS system N-acetylglucosamine-specific EIIC component; N-acetylglucosamine-specific phosphotransferase enzyme IIB component; PTS system N-acetylglucosamine-specific EIIB component [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MLQFLQRIGKALMLPIAVLPAAGLLLRLGQEDVFNIPVMAQAGAAIFDNLALIFAIGVAIGLSVDGSGAAGLAGAIGYLV
LQNTTNALSKTYSAAELNDKLKSVQDLVGSVDPTKLADTMTKVSKAAALTPKINMAILGGIIAGVVAGLLYNKFHKIKLP
EWLGFFAGKRFVPIITSIVMLLLGLVFGQIWPTIQSGIDAVAHGIVNLGSIGAGLFGLLNRLLIPIGLHHVMNTYFWFVL
GDFTNAAGDIVHGDIARFFAKDPSAGMFMTGFFPVMMFGLPAACFAMIAAAKPEKRKMVTGMLGGLALTSFLTGITEPIE
FSFMFLSPVLYGIHAVLTGLSLFITTTLGIHDGFSFSAGAIDYVLNFGIATKPLLLAGIGLIYAAIYFVVFYFLIKKFDL
KTPGREDEEEMAEGEEAPVAGSIGETYVAALGGKENLTVIDNCATRLRLQVKDAGQVNEAALKRAGAKGVMKLSNTSVQV
IVGTNVESVADDMKKHV

Sequences:

>Translated_497_residues
MLQFLQRIGKALMLPIAVLPAAGLLLRLGQEDVFNIPVMAQAGAAIFDNLALIFAIGVAIGLSVDGSGAAGLAGAIGYLV
LQNTTNALSKTYSAAELNDKLKSVQDLVGSVDPTKLADTMTKVSKAAALTPKINMAILGGIIAGVVAGLLYNKFHKIKLP
EWLGFFAGKRFVPIITSIVMLLLGLVFGQIWPTIQSGIDAVAHGIVNLGSIGAGLFGLLNRLLIPIGLHHVMNTYFWFVL
GDFTNAAGDIVHGDIARFFAKDPSAGMFMTGFFPVMMFGLPAACFAMIAAAKPEKRKMVTGMLGGLALTSFLTGITEPIE
FSFMFLSPVLYGIHAVLTGLSLFITTTLGIHDGFSFSAGAIDYVLNFGIATKPLLLAGIGLIYAAIYFVVFYFLIKKFDL
KTPGREDEEEMAEGEEAPVAGSIGETYVAALGGKENLTVIDNCATRLRLQVKDAGQVNEAALKRAGAKGVMKLSNTSVQV
IVGTNVESVADDMKKHV
>Mature_497_residues
MLQFLQRIGKALMLPIAVLPAAGLLLRLGQEDVFNIPVMAQAGAAIFDNLALIFAIGVAIGLSVDGSGAAGLAGAIGYLV
LQNTTNALSKTYSAAELNDKLKSVQDLVGSVDPTKLADTMTKVSKAAALTPKINMAILGGIIAGVVAGLLYNKFHKIKLP
EWLGFFAGKRFVPIITSIVMLLLGLVFGQIWPTIQSGIDAVAHGIVNLGSIGAGLFGLLNRLLIPIGLHHVMNTYFWFVL
GDFTNAAGDIVHGDIARFFAKDPSAGMFMTGFFPVMMFGLPAACFAMIAAAKPEKRKMVTGMLGGLALTSFLTGITEPIE
FSFMFLSPVLYGIHAVLTGLSLFITTTLGIHDGFSFSAGAIDYVLNFGIATKPLLLAGIGLIYAAIYFVVFYFLIKKFDL
KTPGREDEEEMAEGEEAPVAGSIGETYVAALGGKENLTVIDNCATRLRLQVKDAGQVNEAALKRAGAKGVMKLSNTSVQV
IVGTNVESVADDMKKHV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=505, Percent_Identity=52.4752475247525, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787343, Length=502, Percent_Identity=43.2270916334661, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1787908, Length=536, Percent_Identity=36.3805970149254, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010974 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 52570; Mature: 52570

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECCCHHHHHHHHHHCC
>Mature Secondary Structure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EECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]