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The map label for this gene is yfkJ [H]

Identifier: 49183421

GI number: 49183421

Start: 426810

End: 427274

Strand: Direct

Name: yfkJ [H]

Synonym: BAS0393

Alternate gene names: 49183421

Gene position: 426810-427274 (Clockwise)

Preceding gene: 49183418

Following gene: 49183422

Centisome position: 8.16

GC content: 38.49

Gene sequence:

>465_bases
ATGGTTCAAGTATTGTTTGTTTGTCTTGGGAACATTTGCCGTTCTCCAATGGCAGAAGCGATTTTTCGAGATCTTGTCGT
AAAAGAGGGACTCGAAGAGAAAATTGTCATTGATTCTGCAGGAACTGGAGATTGGCATGTTGGCCATCCGCCACATAAAG
GAACACAAAAAATTTTAAAAGAAAATGCAGTCACTTTTGAAGGAATTAAAGCAAGGCAAGTAGAAAAAGAAGACTTAACA
AAGTTTGATTATATTATTGCCATGGACAACAAGAATATAGCAGATTTAAAAAGTTTAGGTAAAACTGGAGGCTATATTGG
TAGGCTGTCCGATTTTGTTCCAGACGGTGGCTGGACAGACGTTCCCGACCCTTACTATACAGGGAATTTCCAAGAAGTAT
ATGACCTTGTAACAGAAGGGTGTGCAAAGCTATTAGCTTTCATTCGAAATGAACAAGGAATATGA

Upstream 100 bases:

>100_bases
TCCTATTAAATTAGTAGGGATTTCCTTTATATTTAATAATTGGTTGTTTATACTATAAGTATATATTAAGAAATGCACCA
AGAAGGGAAGAAACAAAAAT

Downstream 100 bases:

>100_bases
GGAAGCTTAGAAAGAAATACTTTCTAACATAAGAAATGAAAGGGTGAAGGAATATGGCAAAGAAAAATAATATTGCTCGA
AACATTGCGATTGGTGTAGC

Product: low molecular weight phosphotyrosine protein phosphatase family protein

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILKENAVTFEGIKARQVEKEDLT
KFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI

Sequences:

>Translated_154_residues
MVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILKENAVTFEGIKARQVEKEDLT
KFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI
>Mature_154_residues
MVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILKENAVTFEGIKARQVEKEDLT
KFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=148, Percent_Identity=39.8648648648649, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI4757714, Length=148, Percent_Identity=38.5135135135135, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI96304457, Length=76, Percent_Identity=47.3684210526316, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325330, Length=130, Percent_Identity=40, Blast_Score=91, Evalue=8e-20,
Organism=Drosophila melanogaster, GI78706770, Length=154, Percent_Identity=38.3116883116883, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI78706772, Length=154, Percent_Identity=38.3116883116883, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI78711846, Length=165, Percent_Identity=36.3636363636364, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI78706766, Length=148, Percent_Identity=33.7837837837838, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706768, Length=148, Percent_Identity=33.7837837837838, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=36.1538461538462, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648069, Length=151, Percent_Identity=33.7748344370861, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17094; Mature: 17094

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
ENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTD
HCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCC
VPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
ENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTD
HCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCC
VPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]