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The map label for this gene is galE [C]

Identifier: 49183294

GI number: 49183294

Start: 276059

End: 276832

Strand: Direct

Name: galE [C]

Synonym: BAS0263

Alternate gene names: 49183294

Gene position: 276059-276832 (Clockwise)

Preceding gene: 49183289

Following gene: 49183303

Centisome position: 5.28

GC content: 29.33

Gene sequence:

>774_bases
ATGTTGAAGATATATATAGCTTTAGCGAATGTGGATATTATTATTTATTTAGCTGCAACGTCTAATGTAGCAACTTCAAT
TGAAGATGTTTTCGGAGATATAAACAGTAGCTTTTTTTTTCTTAATTTCATGGAAAGCGTTAAAAATTTTCCTATTAAAA
AAATTGTATTAGCATCTTCTGGAGGCACGGTTTATGGTGAACCTGAATATTTACCTATTGATGAGGATCATCCATTAAAA
CCACTTTCTCCTTATGGAATAACAAAAGTGTCGCTTGAAAATTATTTGTACTTTTATAAGAAAAAATATGGAATTGACTA
TGTTGTATGTAGATATTCTAATCCGTATGGAAAATATCAAAATCCTTTAAAGAAAGTTGGGGCAATAAATTGTTTTTTGT
ATCAGCATCTCAGTAATGAAAGGATTAATATATATGGGAATCCACAAGAGATTATTCGAGATTATATTTATATTGATGAT
TTAGTGGAAATCACTATACAACTATCACAATTAAATCGCTTGAAATCTTGTGTGTATAACATAGGGAGCGGCAAGGGTCT
CTCTTTAAAACGAATTATAGTAGAACTGGAGAAATTAACGGAAAGAAAAGTGGACTTTATCTGCTATAAACAAAAGCAAG
AAAATGTTCAAAAAATCATTTTAAATATAGATAGGGTAAGACGAGAATGTAATTGGGAACCGAAAGTGGATTTCAAAAGT
GGAATTAGATTAAATAAGCTATGGATTGAAGAGTTCTTATATAGTAAAAAATAA

Upstream 100 bases:

>100_bases
TTGAAACAAGGTCAAAATGTAAAGGTATTTTCCAGGCATATAAATAATTTCCCTCAAAATATTATAAGTGAGGTCGAATT
TATTAAAGGTGATTTAGCTA

Downstream 100 bases:

>100_bases
TAAACCATGCCCTACTTCTGTATAAGTAGAGCATGGTTTATTATTTTATTTCTTTTTGTATTACCCAAAGGTCTTGATGT
TCCCACCAAAAACCTTCAGT

Product: UDP-glucose 4-epimerase, C-terminus

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLKIYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLK
PLSPYGITKVSLENYLYFYKKKYGIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERINIYGNPQEIIRDYIYIDD
LVEITIQLSQLNRLKSCVYNIGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKS
GIRLNKLWIEEFLYSKK

Sequences:

>Translated_257_residues
MLKIYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLK
PLSPYGITKVSLENYLYFYKKKYGIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERINIYGNPQEIIRDYIYIDD
LVEITIQLSQLNRLKSCVYNIGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKS
GIRLNKLWIEEFLYSKK
>Mature_257_residues
MLKIYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLK
PLSPYGITKVSLENYLYFYKKKYGIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERINIYGNPQEIIRDYIYIDD
LVEITIQLSQLNRLKSCVYNIGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKS
GIRLNKLWIEEFLYSKK

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI56118217, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI189083684, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI7657641, Length=272, Percent_Identity=24.6323529411765, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI42516563, Length=194, Percent_Identity=25.7731958762887, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI48994969, Length=262, Percent_Identity=24.0458015267176, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788353, Length=281, Percent_Identity=24.5551601423488, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=237, Percent_Identity=26.1603375527426, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356223, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 29953; Mature: 29953

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASS
CEEEEEEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECC
GGTVYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKYGIDYVVCRYSNPYGKYQ
CCEEECCCCEECCCCCCCCCCCCCCCEEEEEHHHHHEEHHHHCCCEEEEEEECCCCCHHH
NPLKKVGAINCFLYQHLSNERINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYN
HHHHHHHHHHHHEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKS
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHC
GIRLNKLWIEEFLYSKK
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKIYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASS
CEEEEEEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECC
GGTVYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKYGIDYVVCRYSNPYGKYQ
CCEEECCCCEECCCCCCCCCCCCCCCEEEEEHHHHHEEHHHHCCCEEEEEEECCCCCHHH
NPLKKVGAINCFLYQHLSNERINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYN
HHHHHHHHHHHHEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKS
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHC
GIRLNKLWIEEFLYSKK
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]