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The map label for this gene is alr [H]

Identifier: 49183271

GI number: 49183271

Start: 239722

End: 240891

Strand: Direct

Name: alr [H]

Synonym: BAS0238

Alternate gene names: 49183271

Gene position: 239722-240891 (Clockwise)

Preceding gene: 49183270

Following gene: 49183272

Centisome position: 4.58

GC content: 38.46

Gene sequence:

>1170_bases
ATGGAAGAAGCACCATTTTATCGTGACACTTGGGTGGAAGTGGATTTAGATGCCATTTATAACAACGTTACACATATTAA
AGAATTTATCCCGAGTGATGTAGAAATTTTTGCCGTTGTTAAAGGGAATGCATATGGGCACGATTATGTACCGGTGGCTA
AAATAGCATTAGAAGCGGGGGCGACAAGGTTAGCAGTTGCGTTCTTAGATGAAGCTTTAGTGCTTCGAAGAGCTGGTATT
ACTGCGCCAATTTTGGTGTTAGGTCCTTCTCCTCCTCGTGATATAAATGTAGCTGCTGAAAATGATGTAGCATTAACTGT
TTTTCAAAAGGAATGGGTAGACGAAGCAATCAAACTTTGGGATGGTTCGTCTACGATGAAATACCATATTAATTTCGATA
GTGGTATGGGGAGAATTGGAATACGTGAACGTAAAGAATTAAAAGGATTTTTAAAAAGCTTAGAAGGTGCACCATTCTTA
GAGTTGGAAGGAGTTTATACGCATTTTGCAACAGCAGATGAGGTGGAGACTTCTTACTTTGATAAGCAATATAACACATT
TTTGGAGCAGTTAAGTTGGTTGAAAGAATTCGGAGTGGATCCTAAGTTTGTTCATACAGCTAATAGTGCTGCAACGCTAC
GTTTTCAAGGGATTACATTTAATGCAGTACGAATTGGCATTGCGATGTATGGGTTATCTCCATCTGTAGAAATACGCCCT
TTTTTACCGTTTAAATTAGAACCAGCGCTATCATTGCATACGAAAGTTGCTCATATTAAACAGGTGATTAAAGGGGATGG
AATTAGTTATAACGTCACTTATCGAACGAAAACTGAAGAATGGATTGCGACCGTTGCAATTGGTTATGCAGATGGCTGGC
TTAGAAGATTACAAGGATTTGAAGTACTTGTAAATGGTAAAAGGGTACCGATTGTAGGGCGAGTAACGATGGATCAATTC
ATGATTCACCTTCCTTGTGAAGTGCCTCTTGGTACGAAAGTTACACTCATTGGAAGGCAAGGAGATGAATATATTAGCGC
TACAGAGGTTGCGGAATATTCAGGGACTATTAATTATGAAATTATTACGACGATCAGTTTTCGTGTGCCGAGAATATTTA
TACGGAATGGAAAAGTTGTGGAAGTAATTAATTATTTGAACGATATATAG

Upstream 100 bases:

>100_bases
TATATGTGCACCACGTCTTTTCTTAGTTTGAAGGGTGGATTTCATAAAAGAAGCATATAAAAGAATAAGCTTCGCATATC
GTGTATAAGGAAGTGTATTT

Downstream 100 bases:

>100_bases
AAGGTAGTATGATTTGCTTCTTGTCATGTGAGAGAACTGTTCATTGGTTAAGAATAAGTTCGTTTTTGACGAGAAGCTTT
TTACTTATAGTTACTTTTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MEEAPFYRDTWVEVDLDAIYNNVTHIKEFIPSDVEIFAVVKGNAYGHDYVPVAKIALEAGATRLAVAFLDEALVLRRAGI
TAPILVLGPSPPRDINVAAENDVALTVFQKEWVDEAIKLWDGSSTMKYHINFDSGMGRIGIRERKELKGFLKSLEGAPFL
ELEGVYTHFATADEVETSYFDKQYNTFLEQLSWLKEFGVDPKFVHTANSAATLRFQGITFNAVRIGIAMYGLSPSVEIRP
FLPFKLEPALSLHTKVAHIKQVIKGDGISYNVTYRTKTEEWIATVAIGYADGWLRRLQGFEVLVNGKRVPIVGRVTMDQF
MIHLPCEVPLGTKVTLIGRQGDEYISATEVAEYSGTINYEIITTISFRVPRIFIRNGKVVEVINYLNDI

Sequences:

>Translated_389_residues
MEEAPFYRDTWVEVDLDAIYNNVTHIKEFIPSDVEIFAVVKGNAYGHDYVPVAKIALEAGATRLAVAFLDEALVLRRAGI
TAPILVLGPSPPRDINVAAENDVALTVFQKEWVDEAIKLWDGSSTMKYHINFDSGMGRIGIRERKELKGFLKSLEGAPFL
ELEGVYTHFATADEVETSYFDKQYNTFLEQLSWLKEFGVDPKFVHTANSAATLRFQGITFNAVRIGIAMYGLSPSVEIRP
FLPFKLEPALSLHTKVAHIKQVIKGDGISYNVTYRTKTEEWIATVAIGYADGWLRRLQGFEVLVNGKRVPIVGRVTMDQF
MIHLPCEVPLGTKVTLIGRQGDEYISATEVAEYSGTINYEIITTISFRVPRIFIRNGKVVEVINYLNDI
>Mature_389_residues
MEEAPFYRDTWVEVDLDAIYNNVTHIKEFIPSDVEIFAVVKGNAYGHDYVPVAKIALEAGATRLAVAFLDEALVLRRAGI
TAPILVLGPSPPRDINVAAENDVALTVFQKEWVDEAIKLWDGSSTMKYHINFDSGMGRIGIRERKELKGFLKSLEGAPFL
ELEGVYTHFATADEVETSYFDKQYNTFLEQLSWLKEFGVDPKFVHTANSAATLRFQGITFNAVRIGIAMYGLSPSVEIRP
FLPFKLEPALSLHTKVAHIKQVIKGDGISYNVTYRTKTEEWIATVAIGYADGWLRRLQGFEVLVNGKRVPIVGRVTMDQF
MIHLPCEVPLGTKVTLIGRQGDEYISATEVAEYSGTINYEIITTISFRVPRIFIRNGKVVEVINYLNDI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=378, Percent_Identity=30.1587301587302, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787439, Length=373, Percent_Identity=29.4906166219839, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43663; Mature: 43663

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAPFYRDTWVEVDLDAIYNNVTHIKEFIPSDVEIFAVVKGNAYGHDYVPVAKIALEAG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCC
ATRLAVAFLDEALVLRRAGITAPILVLGPSPPRDINVAAENDVALTVFQKEWVDEAIKLW
CHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHC
DGSSTMKYHINFDSGMGRIGIRERKELKGFLKSLEGAPFLELEGVYTHFATADEVETSYF
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHH
DKQYNTFLEQLSWLKEFGVDPKFVHTANSAATLRFQGITFNAVRIGIAMYGLSPSVEIRP
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECEEEEEEEEEEEEECCCCCCEEEE
FLPFKLEPALSLHTKVAHIKQVIKGDGISYNVTYRTKTEEWIATVAIGYADGWLRRLQGF
CCCEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHEEEEEEEECHHHHHHHHCCC
EVLVNGKRVPIVGRVTMDQFMIHLPCEVPLGTKVTLIGRQGDEYISATEVAEYSGTINYE
EEEECCCEEEEEEEEECCEEEEEECCCCCCCCEEEEEECCCCCCEEHHHHHHHCCEEEEE
IITTISFRVPRIFIRNGKVVEVINYLNDI
EEEEEEEECCEEEEECCCEEHHHHHHHCC
>Mature Secondary Structure
MEEAPFYRDTWVEVDLDAIYNNVTHIKEFIPSDVEIFAVVKGNAYGHDYVPVAKIALEAG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCC
ATRLAVAFLDEALVLRRAGITAPILVLGPSPPRDINVAAENDVALTVFQKEWVDEAIKLW
CHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHC
DGSSTMKYHINFDSGMGRIGIRERKELKGFLKSLEGAPFLELEGVYTHFATADEVETSYF
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHH
DKQYNTFLEQLSWLKEFGVDPKFVHTANSAATLRFQGITFNAVRIGIAMYGLSPSVEIRP
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECEEEEEEEEEEEEECCCCCCEEEE
FLPFKLEPALSLHTKVAHIKQVIKGDGISYNVTYRTKTEEWIATVAIGYADGWLRRLQGF
CCCEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHEEEEEEEECHHHHHHHHCCC
EVLVNGKRVPIVGRVTMDQFMIHLPCEVPLGTKVTLIGRQGDEYISATEVAEYSGTINYE
EEEECCCEEEEEEEEECCEEEEEECCCCCCCCEEEEEECCCCCCEEHHHHHHHCCEEEEE
IITTISFRVPRIFIRNGKVVEVINYLNDI
EEEEEEEECCEEEEECCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA