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The map label for this gene is dppE [H]

Identifier: 49183223

GI number: 49183223

Start: 189516

End: 191126

Strand: Direct

Name: dppE [H]

Synonym: BAS0190

Alternate gene names: 49183223

Gene position: 189516-191126 (Clockwise)

Preceding gene: 49183222

Following gene: 49183225

Centisome position: 3.62

GC content: 32.28

Gene sequence:

>1611_bases
ATGAAGAAGTTTTTATTATTTGTCATTATGACCGTATTAGCAATTACTTCTGTCGCTTGCGGTAAGAAAGAGACGCAAAA
AGCAAGTGCTGGTAAGGGAGAAGGAGATCGATTAGTAACGAATATTAGTAGTGATCCATATACTCTTGATGCTGCTATTT
CGACAGATAGCACGTCAGGTTATGTAATTGGACATTTATTCTCAAGCTTATATACGCAAGATAGCGATGGGAAATATCAA
AATGAATTAGCAGAGAAAGAAGAAGTAAATGCTGATGGAACGGAGTATACAATTCATTTAAAGAAAGATATTAAATGGTC
AGATGGTTCTCCTATTACAGCAAATGACTTTGAATTTGCATGGAAGCGATTATTAAATCCGAAAACGGGTTCTATGAATG
CTACAGAAATGTATTTTATTAAAGGGGCAGAGGCATATAATACTGGAAAAGGTGAAGAAGGCCAAGTTGGTATTCAAGTT
GTTGATCCTCAAACATTAAAGATAACACTTGAGCACCCTGTTTCTTCTATTAAACAAAAGCTAGCAAGTTCATTATTTAT
TCCATTATCTAAAAAATCAATTGATGATAATAATAAATTAAAAACAAATCCAAAAGAGTTAATTACGAACGGACCATTCA
CGTTAAAAGAATGGAAGCATAACCAAGCTATTACAGTGCAAAAAAACAAAGAATATTATGATAAAAAGGTGACATTAAAA
GAAATTGAGTTTCGCATTATTCCAGACTCTAAAACAGCGTACCAATTGTACAAATCAAAAGAATTAGATTTACTAAGTGG
TTTACCACAAGAGATGATTGAGAAAGAAAAAGGAAATAAAGAATATAAGCGTGTTGCAGGATTCTCATCTTATATTTATT
CGTTTAATGTAGAAAAAGAGCCATTCACAAATGCGAAAGTGCGTAAAGCCTTTTCATTAGCAGTTGATCGTAAGTTTATC
GTTGAAAAACTGTATAAGAATAATGCACAAGAAGCATATGCATTCGTTCCAGAAGGAGCAAAAACACAAGGTGGTCGTGA
TTTCCGTAAAGAAAAAGGCGATTATGTTAAATTCGATCCGGAAGAAGCGAAAAAATTATTAGAAGAGGGTATGAAAGAAC
AAGGTTGGTCTACATTACCTGCAGTAACATTGAAATTTACTACAGATACACAACATAAAAAAGTAGCAGAAGCAATGCAA
GAAATGTTTAAGAAAAATCTTGGCGTAGATATTAAGTTAGAAAATAAAGAATGGAAGAGTTACATCGATACATATAAGCA
AAGTGATTTTCAATTAGCTTATATGGGATGGGGAGGTTCTTTATTAGATCCAATTACTAAACTAGATTTATATGCAGGTG
ATGGTCTCAATAACTATGCAAAATGGCATAATAAAGAATTTGATGCTTTAGTAAAAGAAGCCGAAGTTGAACAAAATGAA
GATAAACGTTTTGACTTATTGCATAAAGCAGAAGATATTATGTTTACAGATTCACCGTTAATCCCAATTATATTCCCTTC
TGATTCTTATTTACAAAAAGAATCAGTATCTGGGCTTCAATATTATGTTGGATCTAAACCAGATTTAAGATATGTAAAAA
TAAAGAAGTAG

Upstream 100 bases:

>100_bases
TTTGGAAATACGGACGAAGTATTCCGTAATCCACAACATTCTTATACAAAAACATTATTAGCATCAACACCAAAAATTTC
AGGGTAAAGGGGAATGTAAG

Downstream 100 bases:

>100_bases
GCAACCGCCTACTTCTTTATTTTATTTCTCTTTTATATTCTTTTTTCGTTCCATCAGAGAAGACAACTTCTAACTCGAAT
TTTTGATAGTCTTTATCGAG

Product: oligopeptide ABC transporter oligopeptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDAAISTDSTSGYVIGHLFSSLYTQDSDGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKITLEHPVSSIKQKLASSLFIPLSKKSIDDNNKLKTNPKELITNGPFTLKEWKHNQAITVQKNKEYYDKKVTLK
EIEFRIIPDSKTAYQLYKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQGGRDFRKEKGDYVKFDPEEAKKLLEEGMKEQGWSTLPAVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGLNNYAKWHNKEFDALVKEAEVEQNE
DKRFDLLHKAEDIMFTDSPLIPIIFPSDSYLQKESVSGLQYYVGSKPDLRYVKIKK

Sequences:

>Translated_536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDAAISTDSTSGYVIGHLFSSLYTQDSDGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKITLEHPVSSIKQKLASSLFIPLSKKSIDDNNKLKTNPKELITNGPFTLKEWKHNQAITVQKNKEYYDKKVTLK
EIEFRIIPDSKTAYQLYKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQGGRDFRKEKGDYVKFDPEEAKKLLEEGMKEQGWSTLPAVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGLNNYAKWHNKEFDALVKEAEVEQNE
DKRFDLLHKAEDIMFTDSPLIPIIFPSDSYLQKESVSGLQYYVGSKPDLRYVKIKK
>Mature_536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDAAISTDSTSGYVIGHLFSSLYTQDSDGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKITLEHPVSSIKQKLASSLFIPLSKKSIDDNNKLKTNPKELITNGPFTLKEWKHNQAITVQKNKEYYDKKVTLK
EIEFRIIPDSKTAYQLYKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQGGRDFRKEKGDYVKFDPEEAKKLLEEGMKEQGWSTLPAVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGLNNYAKWHNKEFDALVKEAEVEQNE
DKRFDLLHKAEDIMFTDSPLIPIIFPSDSYLQKESVSGLQYYVGSKPDLRYVKIKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=497, Percent_Identity=31.7907444668008, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI87081878, Length=538, Percent_Identity=29.5539033457249, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1787495, Length=513, Percent_Identity=31.3840155945419, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789966, Length=439, Percent_Identity=28.4738041002278, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787052, Length=505, Percent_Identity=25.7425742574257, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787762, Length=489, Percent_Identity=24.3353783231084, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789887, Length=400, Percent_Identity=24.75, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787551, Length=475, Percent_Identity=20, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60950; Mature: 60950

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDAAISTDSTSG
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCC
YVIGHLFSSLYTQDSDGKYQNELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFA
EEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH
WKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQVVDPQTLKITLEHPVSSIKQK
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHH
LASSLFIPLSKKSIDDNNKLKTNPKELITNGPFTLKEWKHNQAITVQKNKEYYDKKVTLK
HHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCEEHHHCCCCCEEEEECCCHHHHHCEEEE
EIEFRIIPDSKTAYQLYKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKE
EEEEEEECCCCHHHHHHHCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHEEEEECCCCC
PFTNAKVRKAFSLAVDRKFIVEKLYKNNAQEAYAFVPEGAKTQGGRDFRKEKGDYVKFDP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECH
EEAKKLLEEGMKEQGWSTLPAVTLKFTTDTQHKKVAEAMQEMFKKNLGVDIKLENKEWKS
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
YIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGLNNYAKWHNKEFDALVKEAEVEQNE
HHHHHCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHCCCCC
DKRFDLLHKAEDIMFTDSPLIPIIFPSDSYLQKESVSGLQYYVGSKPDLRYVKIKK
CHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHCCCCEEECCCCCCEEEEEEEC
>Mature Secondary Structure
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDAAISTDSTSG
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCC
YVIGHLFSSLYTQDSDGKYQNELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFA
EEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH
WKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQVVDPQTLKITLEHPVSSIKQK
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHH
LASSLFIPLSKKSIDDNNKLKTNPKELITNGPFTLKEWKHNQAITVQKNKEYYDKKVTLK
HHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCEEHHHCCCCCEEEEECCCHHHHHCEEEE
EIEFRIIPDSKTAYQLYKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKE
EEEEEEECCCCHHHHHHHCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHEEEEECCCCC
PFTNAKVRKAFSLAVDRKFIVEKLYKNNAQEAYAFVPEGAKTQGGRDFRKEKGDYVKFDP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECH
EEAKKLLEEGMKEQGWSTLPAVTLKFTTDTQHKKVAEAMQEMFKKNLGVDIKLENKEWKS
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
YIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGLNNYAKWHNKEFDALVKEAEVEQNE
HHHHHCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHCCCCC
DKRFDLLHKAEDIMFTDSPLIPIIFPSDSYLQKESVSGLQYYVGSKPDLRYVKIKK
CHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHCCCCEEECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]