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The map label for this gene is rocF [H]

Identifier: 49183188

GI number: 49183188

Start: 152604

End: 153497

Strand: Direct

Name: rocF [H]

Synonym: BAS0155

Alternate gene names: 49183188

Gene position: 152604-153497 (Clockwise)

Preceding gene: 49183187

Following gene: 49183189

Centisome position: 2.92

GC content: 38.03

Gene sequence:

>894_bases
ATGAAAAAAGAAATTTCGGTTATTGGAGTTCCAATGGATTTAGGGCAGATGCGTCGTGGAGTTGATATGGGACCGAGCGC
AATCCGTTATGCAGGTGTAATTGAAAGAATTGAAGAAATTGGATATGACGTTAAAGATATGGGAGATATATGTATAGAGA
GAGAAAAAGAAGTAGATGTAAATACAAGCTTAAGAAACCTTACACAAGTTGCAACTGTATGTAACGAATTAGCAAGTAAG
GTAGATCATATTATAGAAGAAGGGCGTTTTCCACTTGTATTAGGTGGCGATCATAGTATCGCTATTGGTACATTAGCTGG
TGTGGCGAAACATTATAAAAACCTAGGTGTTATTTGGTACGATGCACATGGTGATTTAAATACAGAAGAAACTTCACCAT
CTGGGAATATTCACGGTATGTCACTTGCAGCAAGTTTAGGGTATGGACATCCCACGCTTGTAGATTTATACGGGGCATAT
CCAAAGGTGAAAAAAGAGAATGTTGTCATTATCGGTGCACGTGCATTAGATGAAGGAGAAAAAGACTTTATTCGCAATGA
AGGTATTAAAGTATTCACAATGCACGAGATTGATCGTATGGGTATGACAGCTGTTATGGAAGAAACAATTGAATATTTAT
CTCATACTGACGGTGTGCATTTATCATTAGATTTAGATGGTCTTGATCCTCATGATGCACCAGGAGTTGGAACACCTGTA
ATTGGTGGCCTATCTTATCGTGAGAGCCATTTAGCAATGGAGATGTTAGCGGAAGCTGATATTGTTACATCTGCGGAGTT
TGTTGAGGTAAATATGATTTTAGATGAGCGAAATAGAACGGCAACAACAGCGGTTGCTTTAATGGGTTCTTTATTCGGTG
AAAAACTAAAATAA

Upstream 100 bases:

>100_bases
GTGAATAATTTGTATATCCATACAGAAAAATGTCGAGTTGAGTCAGACTATATAAAAGATTTAAAATATTTAGTGAAGGC
ACAGAAGGGGGATACTATCT

Downstream 100 bases:

>100_bases
ATGTAAGAAAAGCAACTGAGAAGTTGCTTTTTTTATTTGAAAATAGGCGTATAATAATGATTTATATTATACTGTACGAT
AAGAATGTTTGACATCTTAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNMILDERNRTATTAVALMGSLFGEKLK

Sequences:

>Translated_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNMILDERNRTATTAVALMGSLFGEKLK
>Mature_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNMILDERNRTATTAVALMGSLFGEKLK

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=300, Percent_Identity=40.3333333333333, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4502215, Length=301, Percent_Identity=38.5382059800665, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI37537722, Length=292, Percent_Identity=27.7397260273973, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789306, Length=278, Percent_Identity=25.8992805755396, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71996843, Length=236, Percent_Identity=36.4406779661017, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325146, Length=320, Percent_Identity=30.9375, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24638886, Length=310, Percent_Identity=30.9677419354839, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32338; Mature: 32338

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDV
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTSLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCC
KDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNMILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDV
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTSLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCC
KDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNMILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]