The gene/protein map for NC_005945 is currently unavailable.
Definition Bacillus anthracis str. Sterne chromosome, complete genome.
Accession NC_005945
Length 5,228,663

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The map label for this gene is yxjF [H]

Identifier: 304570532

GI number: 304570532

Start: 3887730

End: 3888506

Strand: Direct

Name: yxjF [H]

Synonym: NA

Alternate gene names: 304570532

Gene position: 3887730-3888506 (Clockwise)

Preceding gene: 49186933

Following gene: 49186943

Centisome position: 74.35

GC content: 38.48

Gene sequence:

>777_bases
ATGGTTACAAATCGAGTTGTTTTTTTAACAGGTGCTGCAAGTGGTATTGGATATGAAATGGGAAACACTTTTGCAAAAGA
AGGTGCAAAAGTTGTTATTACCGATCGTCTTGAAGAACGTGCAAAAGAAGCTGCTGAACAACTACAAAAAGAGGGCTTTC
AAGCTATCGGCTTAAAATGTGATGTTACATCCGAAGAAGAAATAGAAGCATCCATTTCCCAAACTGTTAATCATTTCGGT
TCATTAGACATATTAATTAATAACGCAGGAATGCAACACGTTTCACCAATTGAAGATTTCCCAACCGAAAAATTCGAGCT
ACTAATTAAAATTATGCAAATCGCTCCTTTTATCGCCATTAAGCATGCCTTTCCCATTATGAAAAAGCAAAAATATGGCC
GAATTATTAATGTAGCTTCCATTAATGGCCTCGTTGGATTCGCTGGAAAAGCTGCTTATAATAGCGCAAAACATGGCGTA
ATTGGATTAACAAAAGTTGCCGCTTTAGAAGGGGCTACTCACGGAATTACTGTTAATGCACTTTGTCCCGGTTATGTCGA
TACCCCTCTCGTACGGAATCAATTACAAGACTTGGCCACCACACGAAATGTACCACTTGAAAATGTTTTAGAGGATGTCA
TTTATCCACTTGTCCCACAAAAACGCTTATTACAAGTACAAGAGATTGCTGATTATGCGATGTTTTTAGCGAGCGAAAAA
GCGAAAGGTATAACTGGACAAGCTGTCGTTATCGATGGTGGTTATACCGCTCAATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 3-hydroxybutyrate dehydrogenase

Products: acetoacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:
NA

Sequences:

>Translated_258_residues
MVTNRVVFLTGAASGIGYEMGNTFAKEGAKVVITDRLEERAKEAAEQLQKEGFQAIGLKCDVTSEEEIEASISQTVNHFG
SLDILINNAGMQHVSPIEDFPTEKFELLIKIMQIAPFIAIKHAFPIMKKQKYGRIINVASINGLVGFAGKAAYNSAKHGV
IGLTKVAALEGATHGITVNALCPGYVDTPLVRNQLQDLATTRNVPLENVLEDVIYPLVPQKRLLQVQEIADYAMFLASEK
AKGITGQAVVIDGGYTAQ
>Mature_258_residues
MVTNRVVFLTGAASGIGYEMGNTFAKEGAKVVITDRLEERAKEAAEQLQKEGFQAIGLKCDVTSEEEIEASISQTVNHFG
SLDILINNAGMQHVSPIEDFPTEKFELLIKIMQIAPFIAIKHAFPIMKKQKYGRIINVASINGLVGFAGKAAYNSAKHGV
IGLTKVAALEGATHGITVNALCPGYVDTPLVRNQLQDLATTRNVPLENVLEDVIYPLVPQKRLLQVQEIADYAMFLASEK
AKGITGQAVVIDGGYTAQ

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=30.2325581395349, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=35.9375, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=28.735632183908, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=32.618025751073, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI31542939, Length=260, Percent_Identity=28.4615384615385, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=26.2548262548263, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI4504505, Length=188, Percent_Identity=31.9148936170213, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.1587301587302, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=30.7984790874525, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=31.6582914572864, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=29.0196078431373, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=26.7175572519084, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI40254986, Length=186, Percent_Identity=31.7204301075269, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.3867403314917, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI142976729, Length=226, Percent_Identity=27.8761061946903, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=29.7979797979798, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=32.5581395348837, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI210032110, Length=232, Percent_Identity=27.5862068965517, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=27.0742358078603, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4503817, Length=209, Percent_Identity=26.7942583732057, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4758504, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI310128830, Length=241, Percent_Identity=25.3112033195021, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI310115468, Length=241, Percent_Identity=25.3112033195021, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40807363, Length=247, Percent_Identity=25.5060728744939, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI109715829, Length=194, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI25282469, Length=219, Percent_Identity=26.9406392694064, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=24.904214559387, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=23.4375, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI83715985, Length=175, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40548397, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI225579078, Length=208, Percent_Identity=26.4423076923077, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=31.4516129032258, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=34.4, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.4630350194552, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=30.6772908366534, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.0158102766798, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=30.46875, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=30.2325581395349, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=28.2352941176471, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=30.46875, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.4591439688716, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787820, Length=153, Percent_Identity=28.7581699346405, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=26.8041237113402, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=34.3873517786561, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=30.8880308880309, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=30.0380228136882, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=32.3943661971831, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=26.6409266409266, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982365, Length=188, Percent_Identity=32.4468085106383, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=30.3703703703704, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=31.9148936170213, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=30.9701492537313, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=30.1587301587302, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=30.1587301587302, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=200, Percent_Identity=30.5, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.7924528301887, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=274, Percent_Identity=29.1970802919708, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17558006, Length=264, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=31.1111111111111, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=29.6703296703297, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=30.03663003663, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=27.7978339350181, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=30.2158273381295, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=187, Percent_Identity=28.3422459893048, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=29.2418772563177, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=25.4901960784314, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558628, Length=188, Percent_Identity=30.3191489361702, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=208, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=232, Percent_Identity=24.5689655172414, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.1954887218045, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=30.4182509505703, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=196, Percent_Identity=31.6326530612245, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=228, Percent_Identity=32.4561403508772, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=26.7441860465116, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=31.3725490196078, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.596837944664, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=34.5098039215686, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=33.59375, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=30.7392996108949, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=34.6456692913386, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=34.0425531914894, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=30.5418719211823, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=29.8429319371728, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=28.125, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24581726, Length=191, Percent_Identity=29.3193717277487, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=26.7676767676768, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=31.3725490196078, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364892, Length=163, Percent_Identity=27.6073619631902, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=163, Percent_Identity=26.3803680981595, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571387, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921754, Length=207, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24586328, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI22024069, Length=232, Percent_Identity=28.448275862069, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356301, Length=195, Percent_Identity=25.1282051282051, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=242, Percent_Identity=26.8595041322314, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076371, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.30

Molecular weight: Translated: 27887; Mature: 27887

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MVTNRVVFLTGAASGIGYEMGNTFAKEGAKVVITDRLEERAKEAAEQLQKEGFQAIGLKC
CCCCEEEEEEECCCCCCHHHCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCEEE
DVTSEEEIEASISQTVNHFGSLDILINNAGMQHVSPIEDFPTEKFELLIKIMQIAPFIAI
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
KHAFPIMKKQKYGRIINVASINGLVGFAGKAAYNSAKHGVIGLTKVAALEGATHGITVNA
HHHHHHHHHHHCCCEEEEEECCCHHCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
LCPGYVDTPLVRNQLQDLATTRNVPLENVLEDVIYPLVPQKRLLQVQEIADYAMFLASEK
ECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AKGITGQAVVIDGGYTAQ
CCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MVTNRVVFLTGAASGIGYEMGNTFAKEGAKVVITDRLEERAKEAAEQLQKEGFQAIGLKC
CCCCEEEEEEECCCCCCHHHCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCEEE
DVTSEEEIEASISQTVNHFGSLDILINNAGMQHVSPIEDFPTEKFELLIKIMQIAPFIAI
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
KHAFPIMKKQKYGRIINVASINGLVGFAGKAAYNSAKHGVIGLTKVAALEGATHGITVNA
HHHHHHHHHHHCCCEEEEEECCCHHCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
LCPGYVDTPLVRNQLQDLATTRNVPLENVLEDVIYPLVPQKRLLQVQEIADYAMFLASEK
ECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AKGITGQAVVIDGGYTAQ
CCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-3-hydroxybutanoate; NAD+

Specific reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]