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The map label for this gene is sdhB [H]

Identifier: 46447475

GI number: 46447475

Start: 2200648

End: 2201421

Strand: Reverse

Name: sdhB [H]

Synonym: pc1841

Alternate gene names: 46447475

Gene position: 2201421-2200648 (Counterclockwise)

Preceding gene: 46447476

Following gene: 46447474

Centisome position: 91.18

GC content: 39.15

Gene sequence:

>774_bases
TTGATGGTTCGAACATACATTTTAAAAATATATCGGGGAGAACCGGGATCTCAATATTGGGAAGAATTTGAACTTGCTTT
AATTCCTTATGCGAATGTGATTTCTTCATTAATGGAAATCCAACGCAACCCTATCAATATTAAAGGGGAAAAAGTCAAAC
CTGTCGTATGGGAGTCAGGTTGTTTAGAAGAAGTTTGCGGGTCTTGTTCAATGCTTATCAATGCTTATCCTCGGCAAGCT
TGCACAGCTCTTATTGAACCAATTTTGAATGAAACAAAGAATTTGATTATTACTTTAGCGCCTCTGACCAAATTTCCTTT
AGTGAGAGATTTGATTGTAGATCGTAGTCGCATGTTTGAAAATTTAAAAAAAGTGCATGCATGGATTGATGTCGACGGAA
CCTACCAGCAAGGTCCAGGACCAAATATTGGTCCAGAAAAGCAAAAAGTGATGTATTCTTTAGCAACCTGCATGACTTGC
GGCTGTTGCTCCGAAGCCTGTCCTCAAGTTAACATGCATTCTCCGTTTATAGGCCCTGCGGCAATTTCGCAAGTCCGCTT
ATTTAATGCAAACCCGATTGGAAAAACGCAAAAAGAAAAGCGTTTAAGGCCTTTGATGCAGGAAGGGGGAGTGAATGATT
GTGGAAATAATCAAAACTGCGTGAGGGTTTGTCCAAAAGACATTCCCTTAACAGATTCTATTGCAACAATTAGTCGCGAT
GTCACAAAACAAGCAATTGAAGATCTTTTTAGTTTTCCTGATAGACAAGACTAA

Upstream 100 bases:

>100_bases
AACCTATTCAAAGAGATTATACACAGGCTAAAAAAATTAAACCCAAATTAGAAAATATCCCTGCCAATCTTATTTTACCT
ATTTAATACCTAGGAGATTT

Downstream 100 bases:

>100_bases
CCATTCATTTAATAATTATTAATTAAAGTTAAAATACTAATGACTGTCAATTAATAATTTGTTATTATATTAAATTTAAT
TTTTTTAATTCTATAGGATA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MMVRTYILKIYRGEPGSQYWEEFELALIPYANVISSLMEIQRNPINIKGEKVKPVVWESGCLEEVCGSCSMLINAYPRQA
CTALIEPILNETKNLIITLAPLTKFPLVRDLIVDRSRMFENLKKVHAWIDVDGTYQQGPGPNIGPEKQKVMYSLATCMTC
GCCSEACPQVNMHSPFIGPAAISQVRLFNANPIGKTQKEKRLRPLMQEGGVNDCGNNQNCVRVCPKDIPLTDSIATISRD
VTKQAIEDLFSFPDRQD

Sequences:

>Translated_257_residues
MMVRTYILKIYRGEPGSQYWEEFELALIPYANVISSLMEIQRNPINIKGEKVKPVVWESGCLEEVCGSCSMLINAYPRQA
CTALIEPILNETKNLIITLAPLTKFPLVRDLIVDRSRMFENLKKVHAWIDVDGTYQQGPGPNIGPEKQKVMYSLATCMTC
GCCSEACPQVNMHSPFIGPAAISQVRLFNANPIGKTQKEKRLRPLMQEGGVNDCGNNQNCVRVCPKDIPLTDSIATISRD
VTKQAIEDLFSFPDRQD
>Mature_257_residues
MMVRTYILKIYRGEPGSQYWEEFELALIPYANVISSLMEIQRNPINIKGEKVKPVVWESGCLEEVCGSCSMLINAYPRQA
CTALIEPILNETKNLIITLAPLTKFPLVRDLIVDRSRMFENLKKVHAWIDVDGTYQQGPGPNIGPEKQKVMYSLATCMTC
GCCSEACPQVNMHSPFIGPAAISQVRLFNANPIGKTQKEKRLRPLMQEGGVNDCGNNQNCVRVCPKDIPLTDSIATISRD
VTKQAIEDLFSFPDRQD

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=197, Percent_Identity=27.9187817258883, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1790596, Length=215, Percent_Identity=29.7674418604651, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786943, Length=189, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17533915, Length=207, Percent_Identity=25.1207729468599, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322987, Length=199, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137106, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643156, Length=229, Percent_Identity=27.0742358078603, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28800; Mature: 28800

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVRTYILKIYRGEPGSQYWEEFELALIPYANVISSLMEIQRNPINIKGEKVKPVVWESG
CCHHHEEHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
CLEEVCGSCSMLINAYPRQACTALIEPILNETKNLIITLAPLTKFPLVRDLIVDRSRMFE
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHH
NLKKVHAWIDVDGTYQQGPGPNIGPEKQKVMYSLATCMTCGCCSEACPQVNMHSPFIGPA
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
AISQVRLFNANPIGKTQKEKRLRPLMQEGGVNDCGNNQNCVRVCPKDIPLTDSIATISRD
HHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
VTKQAIEDLFSFPDRQD
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMVRTYILKIYRGEPGSQYWEEFELALIPYANVISSLMEIQRNPINIKGEKVKPVVWESG
CCHHHEEHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
CLEEVCGSCSMLINAYPRQACTALIEPILNETKNLIITLAPLTKFPLVRDLIVDRSRMFE
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHH
NLKKVHAWIDVDGTYQQGPGPNIGPEKQKVMYSLATCMTCGCCSEACPQVNMHSPFIGPA
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
AISQVRLFNANPIGKTQKEKRLRPLMQEGGVNDCGNNQNCVRVCPKDIPLTDSIATISRD
HHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
VTKQAIEDLFSFPDRQD
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]