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The map label for this gene is yhdH [H]

Identifier: 46446894

GI number: 46446894

Start: 1503486

End: 1504886

Strand: Reverse

Name: yhdH [H]

Synonym: pc1260

Alternate gene names: 46446894

Gene position: 1504886-1503486 (Counterclockwise)

Preceding gene: 46446897

Following gene: 46446888

Centisome position: 62.33

GC content: 38.76

Gene sequence:

>1401_bases
ATGCAAAAACAAAGAGAGCACTGGAGTTCACATTTAGGATTTATTCTTGCGGCAGCGGGATCGGCAATTGGTCTCGGAAC
GTTATGGAAATTTCCTTATGTCACAGGTGAAAACGGTGGAGGGCTCTTTGTTTTTATTTATATTTTATGCACGTTTTTTA
TTGGAGTTCCAGTTTTTATTGCGGAATTGATTTTGGGTCGAAAAGCCCAACGTGGAGCTGTTGGCATTTTTGCAAGCTTA
GCTAATAACTCTGCTGCTTGGAAAACTGTGGGTTGGTTAGGAGTTGCCTCTTCTTTTTTAATCATGTCTTTTTATAGTAT
TTTAGCGGGATGGGGGCTCAATTACATTTTCATGTCTCTCAGTCAATTTTACAAGGATCGGACAGCCCAAGAAATTTCAG
GGGTTTTTGACATCCTTGCTTCTTCAGCTGATATCACTTTATTCTGGCATTTTCTCTTCACGGCATTGACAGCCGCCGTC
GTTTATCGAGGCATTCGTCAAGGAATTGAGTATTGGAGCCGCTTTATGACGATTGGTCTATTAATTATTCTTTTAAGTAT
GTGTGCGTATGCTTTCACCCTTCCAGGATTTCGAGAAGGAGTTAATTTTATTTTCTATCCAGATTTATCTCGTTTTAAAC
CCTCTGCTGCTATTGATGCTCTCGGGCTATCTTTCTTTACGCTTAGTTTAGGTCAAGGGATCATGTTGACTTACGGGAGC
TATATGAGAAGAGGGGACAATATTCCTAAAACGGCAGTGATCATAGGTGTCATGATTGTATTGATTTCTTTATTGGCAGG
CCTCATGATTTTCCCTATTATTTTTTCTTTTGGATTTGCACCCGAAGCAGGTCCTGGGCTTGTCTTCAAAACATTACCGG
TTTTATTTGCTCAGTTGCCGGGAGCTCTTTTTATTTCTACCGCATTTTTCGTGTTATTTGTGTTTACGGCACTCACTTCT
GCTGTCGCTTTAATCGAAGTTGTCACAGCAAATTTTACTGATTTACTCGGTTGGTCACGTCAAAAAGCTGTTTTAATTGT
GTCGATTAGTTGTTTTATATTTGGTATTCCTAGCGCATTATCTAATACAAATACGTTATTTGCAAACTGGCCCGCCATTT
ATGGAAAAACTTTTTTTCAAACTATTGATGATTTGGTTACTCTTTGGTTTTTACCTATTGGAGGGTTATTAGTGTCTATT
TTTACGGGTTGGGTTTTAGATAAAGAATTAGCGAAAGAGGAGTTTTCTTCTGGTACGACCATGCGTTGGTTATGGCACCC
GTGGATTTTCTTTATTCGTTGGGTTGCTCCCATTGCTATTGTATTTATCATTCTACAGCAGAGTGGTTTGATTGATATCG
ACACTTATTTCAGTCAGAGAAAAGTAATAAGTCATTTATAA

Upstream 100 bases:

>100_bases
CGCCATCTACGTCTAACACACAAGCAAGTTAAAATTTGTTTGGAGTCGTTTTTCGCCTAGTACCAAATCAATTGTATTCA
TTAATTCGGAGACAAATAAT

Downstream 100 bases:

>100_bases
ACAGGATATTGAGAAAATATTTATAAATTCTAGTAATAGTTTTAAGTAAAAAAATAAAGAAAAATGTTAACATAATACAG
ACAGAGTTAAATGAGCAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQKQREHWSSHLGFILAAAGSAIGLGTLWKFPYVTGENGGGLFVFIYILCTFFIGVPVFIAELILGRKAQRGAVGIFASL
ANNSAAWKTVGWLGVASSFLIMSFYSILAGWGLNYIFMSLSQFYKDRTAQEISGVFDILASSADITLFWHFLFTALTAAV
VYRGIRQGIEYWSRFMTIGLLIILLSMCAYAFTLPGFREGVNFIFYPDLSRFKPSAAIDALGLSFFTLSLGQGIMLTYGS
YMRRGDNIPKTAVIIGVMIVLISLLAGLMIFPIIFSFGFAPEAGPGLVFKTLPVLFAQLPGALFISTAFFVLFVFTALTS
AVALIEVVTANFTDLLGWSRQKAVLIVSISCFIFGIPSALSNTNTLFANWPAIYGKTFFQTIDDLVTLWFLPIGGLLVSI
FTGWVLDKELAKEEFSSGTTMRWLWHPWIFFIRWVAPIAIVFIILQQSGLIDIDTYFSQRKVISHL

Sequences:

>Translated_466_residues
MQKQREHWSSHLGFILAAAGSAIGLGTLWKFPYVTGENGGGLFVFIYILCTFFIGVPVFIAELILGRKAQRGAVGIFASL
ANNSAAWKTVGWLGVASSFLIMSFYSILAGWGLNYIFMSLSQFYKDRTAQEISGVFDILASSADITLFWHFLFTALTAAV
VYRGIRQGIEYWSRFMTIGLLIILLSMCAYAFTLPGFREGVNFIFYPDLSRFKPSAAIDALGLSFFTLSLGQGIMLTYGS
YMRRGDNIPKTAVIIGVMIVLISLLAGLMIFPIIFSFGFAPEAGPGLVFKTLPVLFAQLPGALFISTAFFVLFVFTALTS
AVALIEVVTANFTDLLGWSRQKAVLIVSISCFIFGIPSALSNTNTLFANWPAIYGKTFFQTIDDLVTLWFLPIGGLLVSI
FTGWVLDKELAKEEFSSGTTMRWLWHPWIFFIRWVAPIAIVFIILQQSGLIDIDTYFSQRKVISHL
>Mature_466_residues
MQKQREHWSSHLGFILAAAGSAIGLGTLWKFPYVTGENGGGLFVFIYILCTFFIGVPVFIAELILGRKAQRGAVGIFASL
ANNSAAWKTVGWLGVASSFLIMSFYSILAGWGLNYIFMSLSQFYKDRTAQEISGVFDILASSADITLFWHFLFTALTAAV
VYRGIRQGIEYWSRFMTIGLLIILLSMCAYAFTLPGFREGVNFIFYPDLSRFKPSAAIDALGLSFFTLSLGQGIMLTYGS
YMRRGDNIPKTAVIIGVMIVLISLLAGLMIFPIIFSFGFAPEAGPGLVFKTLPVLFAQLPGALFISTAFFVLFVFTALTS
AVALIEVVTANFTDLLGWSRQKAVLIVSISCFIFGIPSALSNTNTLFANWPAIYGKTFFQTIDDLVTLWFLPIGGLLVSI
FTGWVLDKELAKEEFSSGTTMRWLWHPWIFFIRWVAPIAIVFIILQQSGLIDIDTYFSQRKVISHL

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=407, Percent_Identity=26.7813267813268, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI188528618, Length=397, Percent_Identity=25.6926952141058, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI171184408, Length=416, Percent_Identity=24.7596153846154, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI171184406, Length=416, Percent_Identity=24.7596153846154, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI171184404, Length=416, Percent_Identity=24.7596153846154, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI21361581, Length=400, Percent_Identity=25, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI197276623, Length=384, Percent_Identity=25.2604166666667, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI54607094, Length=384, Percent_Identity=25.2604166666667, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI194018524, Length=299, Percent_Identity=28.4280936454849, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI7657587, Length=412, Percent_Identity=25, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI289191351, Length=384, Percent_Identity=25.78125, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4557046, Length=384, Percent_Identity=25.78125, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI289191377, Length=384, Percent_Identity=25.78125, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=25.7425742574257, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4507041, Length=408, Percent_Identity=24.0196078431373, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI51468073, Length=299, Percent_Identity=24.7491638795987, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI5032097, Length=413, Percent_Identity=24.6973365617433, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI58219014, Length=309, Percent_Identity=24.9190938511327, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI11181770, Length=320, Percent_Identity=26.25, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI67782317, Length=420, Percent_Identity=24.2857142857143, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI67782313, Length=420, Percent_Identity=24.2857142857143, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI67782315, Length=420, Percent_Identity=24.2857142857143, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI134304856, Length=410, Percent_Identity=24.8780487804878, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI218563756, Length=413, Percent_Identity=23.9709443099274, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI21361693, Length=122, Percent_Identity=31.9672131147541, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI12408638, Length=293, Percent_Identity=25.2559726962457, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI197276625, Length=119, Percent_Identity=33.6134453781513, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI92859670, Length=118, Percent_Identity=36.4406779661017, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI6005715, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI289191353, Length=236, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=439, Percent_Identity=26.1958997722096, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25146584, Length=412, Percent_Identity=22.5728155339806, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17554804, Length=375, Percent_Identity=24, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71995588, Length=411, Percent_Identity=22.3844282238443, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17569475, Length=437, Percent_Identity=22.4256292906178, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI133952791, Length=118, Percent_Identity=34.7457627118644, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17542050, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI212642127, Length=102, Percent_Identity=36.2745098039216, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550877, Length=417, Percent_Identity=27.3381294964029, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI45551183, Length=417, Percent_Identity=27.3381294964029, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI17136952, Length=421, Percent_Identity=25.41567695962, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI281364394, Length=421, Percent_Identity=25.41567695962, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574704, Length=421, Percent_Identity=25.41567695962, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136950, Length=421, Percent_Identity=25.41567695962, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574702, Length=421, Percent_Identity=25.41567695962, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24762620, Length=421, Percent_Identity=25.6532066508314, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19921936, Length=406, Percent_Identity=25.615763546798, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24652942, Length=402, Percent_Identity=25.3731343283582, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45551088, Length=402, Percent_Identity=25.3731343283582, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24639514, Length=512, Percent_Identity=24.0234375, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI221329674, Length=512, Percent_Identity=24.0234375, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24661428, Length=381, Percent_Identity=25.1968503937008, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582567, Length=420, Percent_Identity=26.6666666666667, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639853, Length=424, Percent_Identity=25.7075471698113, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281365034, Length=414, Percent_Identity=24.1545893719807, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639516, Length=532, Percent_Identity=23.1203007518797, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921352, Length=420, Percent_Identity=24.047619047619, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24584353, Length=420, Percent_Identity=24.047619047619, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24655079, Length=303, Percent_Identity=23.4323432343234, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363702, Length=350, Percent_Identity=27.4285714285714, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281363700, Length=400, Percent_Identity=26.75, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281364136, Length=518, Percent_Identity=22.7799227799228, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24654186, Length=122, Percent_Identity=31.1475409836066, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582569, Length=379, Percent_Identity=25.065963060686, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 51636; Mature: 51636

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure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EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]