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The map label for this gene is rpoC

Identifier: 46446239

GI number: 46446239

Start: 742175

End: 746341

Strand: Direct

Name: rpoC

Synonym: pc0605

Alternate gene names: 46446239

Gene position: 742175-746341 (Clockwise)

Preceding gene: 46446238

Following gene: 46446240

Centisome position: 30.74

GC content: 39.62

Gene sequence:

>4167_bases
ATGTCTGAAAGAAATCAGCAAGATGGACAATTTGATAAATTGACCATTAAAATTGCCTCTGACGATGTCATACGTAATGA
GTGGTCCCGCGGAGAGATTAAAAAACCTGAAACGATTAACTACCGAACATTTAAACCTGAAAAAGGTGGTCTTTTTTGCG
AAAAAATCTTTGGACCCACACGTGACTGGGAATGTGCTTGCGGAAAATACAAAAAAATTAAACACAAAGGAATTGTTTGC
GATCGTTGTGGTGTGGAAGTTACTTTATCCAAAGTTCGTCGTGAACGAATGGCTCACATTGATTTAGCCGTTCCAGTTGT
TCATATTTGGTTTTTTAAAACAATGCCTTCTCGTATTGGTAATGTTCTCGGAATGACATCCGCCGATCTTGAACGGGTGA
TTTATTATGAAGAGTATGTTGTCATCAATCCAGGCCAAACGGATTTAGAAAGAAAGCAGCTATTAAACGACACTGAATAT
CGTGAAGCACAAGAAAAATGGGGGCGCGATAGCTTTGTGGCAAAAATGGGTGGCGAAGCCATTCGCGACCTCTTAGCGAG
CGAAGATCTACAAACTCAATTGGTAGAATTAAAAGACAAACTTCGTAAAACTAAATCGCAGCAAGCTAGAATGAAGTTGG
CGAAGCGTTTGAAAATTATTGAAAGTTTTGTTTCTTCGGATAACAAACCTGAATGGATGATCATGTCTTGTGTTCCTGTG
ATTCCACCTGATTTACGTCCTTTGGTTCCTCTGGATGGTGGTCGCTTTGCTACGTCTGATTTAAATGATCTTTATCGCCG
TGTGATTAACCGAAACAACCGTTTAAAAGCTATTTTAAAGCTCAAAACACCTGATGTAATCGTACGCAATGAAAAACGTA
TGTTACAAGAAGCTGTGGATGCTTTGTTTGATAACGGTCGCCATGGACATCCTGTTATGGGAGCTGGTAATCGCCCCTTA
AAGTCATTATCTGAAATGTTAAAAGGAAAGCAAGGACGTTTCCGTCAGAACTTACTTGGTAAACGGGTGGATTATTCAGG
TCGATCGGTTATTATTGTTGGTCCAGAATTGAAGTTCAATCAGTGTGGATTACCTAAATTAATGGCTCTTGAATTGTTTG
AACCCTTCATTGTAAAGAGACTTAAAGATCAAGGGTATGTTTATACGATTCGTTCAGCAAAAAAAATGATTCAGAGGCAT
GCTCCAGAAGTTTGGGATGTGTTAGAAGATATCATTAAAGGTCATCCAGTATTATTAAACCGCGCGCCAACGCTTCACCG
TTTAGGTATTCAAGCTTTTGAACCGGTTTTGATTGAAGGTAAAGCGATTCGCATTCATCCGCTTGTTTGTTCGGCATTTA
ACGCGGACTTTGACGGTGACCAAATGGCCGTTTATGTTCCTCTTTCTATTGAAGCACAGTTGGAAGCAAAATTGTTAATG
ATGGCACCTGATAATATTTTCTTACCATCTTCAGGTAAGCCTGTTGCCGTTCCTTCTCAGGATATGACACTCGGTTTGTA
CTATTTAATGCTAGACCCTCTTTATATTCGAGAAAATCATGAATTAAAAACACGAGTTTTTCGAGATAGCGAAGAAGTAC
TGCTGGCTCTACAAGCAAGTGGTAGTTATAACTGGTATGAAGAAGGAAGCAAAAGTCCGAATGGAGAAAATCGTTCCGAT
TACTTAAGAGGAATTCGTATTCATGAAAAAATTAAATTACGAACAGAAAATGGGATTATTGAGACAACACCTGGACGTGT
CGTTTTCAACACGATTGTTCCGAAAGAACTAGGTTTCCAAAACTATAGTTTACCTAAAAAGAAAATGGGTGAACTCGTTA
TGCAGTGCTATAAAAAGGCAGGACTCGAGGCAACGGTTCGTTTCTTAGATAATCTAAAAAGCATAGGTTTTGCGGAAGCG
ACTAAATCAGCTCTTTCGATGGGTGTTTGCGATGTAAAAATTCCGACAATTAAGCAAAAAATCTTACATGATGCTCATGA
ACGCGTTGCTGTAGTCAGAAAACAGTACGAAGATGGTATCATAACTGAAGGGGAACGCTACTCTAAAACAATTAGTATTT
GGACAGAGGTTTCAGATGTTCTTTCAGAAGAATTATTTAAGCTAATTAGTGAAGTTAAAGATAGCACAATGAACCCACTT
TACTTAATGATGGATTCGGGTGCTCGTGGTAATAAATCGCAGATCAGACAGCTTGGAGCTCTCCGTGGTTTGATGGCAAA
ACCATCTGGCGACATCATTGAATCGCCGATCACTTCTAACTTTAGAGAAGGGCTATCGGTGATTGAGTTTTCTATTTCAT
CTCATGGTGCTCGTAAAGGACTGGCAGATACAGCGCTTAAAACAGCTGACTCAGGCTATTTGACTCGCCGTTTAGTCGAT
GTGGCTCAAGATGTGATCATTACAGAAGATGATTGTGGAACATTAAACGGAATTGATGTTTCAGCGATTAAGCAAGGTCA
AGAAGAGTTACTACCTTTGAAAGACCGTATTTTTGGACGTACCGTTTGTGAAGATATTTATCAACCAGGTGATAGCACGA
AATTGCTTGCTAAGAGTGGAGACACATTAACTGTTCTTCAAGCTGAAGCTATCGACGACTCAGGAATTGAAAGTATTCGA
ATTCGTTCTGTGTTGACATGTGAAACAAGACGAGGGGTCTGTGCAAAGTGTTATGGAATTAATTTAGCTAATAGCCGTTC
AATAAGCATGGGTGAAGCTGTTGGTATTATTGCAGCTCAGTCAATAGGTGAACCAGGAACACAGTTAACAATGCGTACCT
TCCACTTGGGTGGTATTGCATCTGCTGGTTTAACTCCAGAGATTGTTGCAGATGATAATGGTATACTTGTTTACACAGAT
TTGCGTACTGTGAAAACTGATGAGGGGAATTGGGTTGCTTTAAATAAAAATGGTAGACTTAATATTGTTAAAGATGAAGG
GCGTACCTTAGATGAATATAAGAAGCTACTATCGACGAAATCGATCGAACCTTTGCAAGCATTTAACGTAGAACTCGGAA
CAAAGATTCTTCTTGAAGAGGGAACAAAAGTTAAACCGGGTACTCGTGTTGCCGAGTGGGAACAACATAATATTCCAATT
ATTTGCGATCGCCCAGGTTATGTTCGTTATGAAGATTTGGTAGAAGGACTTTCTACTGAACGTGACGTAAATAAACAAAC
AGGTCAGGCAGAATTGATTGTAAAACAACATCGGGGTGAGTTACATCCTCAAGTTGCGATTTATGCTGATCAGGCTTGCG
AAGATCTTGTAGGTACATATCCCTTACCTGCTGGAGCAATCATTTCAGTTGAAGAAGGTGAATTTGCTACAGCTGGTAAG
ATGCTTGCACGTCTTCCAAGAAGTGCTATTAAGACAAAAGACATTACTGGGGGGCTTCCACGTGTGGCGGAGTTATTCGA
AGCACGTAAACCTAAAGATTCAGCAGAAATTGCTAAAATTGATGGGGTTGTGGACTTCCGAGGTGTTCAGAAAAACAAAC
GCATTGTCGTTGTTCGCGATGAAATGACAGGAATGGAAGAGGAACATCTTATCTCGCATACTAAGCACTTAATTATTCAA
CGTGGCGACCATGTTGTTAAAGGCCAACAATTGACAGATGGATTAGTTATCCCTCATGAAATTCTTGACATTTGTGGTGT
TCGTGAACTTCAAAAGTATTTGGTTAATCAAGTACAAGAAGTTTATCGCCTACAAGGGGTAGACATCAATGATAAACATA
TTGAAATTATTGTACGTCAAATGTTGAAGAAAGTTCGCGTCATTGATCCAGGCGACACAAGTCTTCTATATGGTGAAGAA
GTTGATAAGAAAGAGTTCGAAGTTGAAAACCAAAAAGTTAGTCAAGAAGGTGGTAAGGCTGCCCAAGCAACACCAGTTCT
ACTTGGTATAACTAAAGCTTCTTTGAGTACGGAATCCTTTATTTCAGCTGCTTCATTCCAAGATACAACACGTGTCTTAA
CAGAAGCTGCCTGTGCGGGTAAAACAGACTATTTAGTTGGTTTTAAAGAAAATGTCATCATGGGACACATTATTCCTGGT
GGAACAGGTTTTGATCGCCATAAACGAGTTAAAATGTTCGTAGATAGCGAGCAAGAGCAAGGATTGGAATTCAATTTTGC
GGATTAA

Upstream 100 bases:

>100_bases
TACCGAAAAAGAAGAAATGCCATTAGGTGTTTCTTCTTATCTGAAAAAGTATCTATTTTGATCTGCTTAAAAATTTAAAC
TAATTTGTTAGGAGACATAC

Downstream 100 bases:

>100_bases
TTAAGCTCGTGAATTGTGTATTTCATTGCACAGACTGTTTGCAGTCTGTGCTTTTTTTTTTACTAAATAAATTTTTAATA
TGAATTTTTATGATTAATCA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1388; Mature: 1387

Protein sequence:

>1388_residues
MSERNQQDGQFDKLTIKIASDDVIRNEWSRGEIKKPETINYRTFKPEKGGLFCEKIFGPTRDWECACGKYKKIKHKGIVC
DRCGVEVTLSKVRRERMAHIDLAVPVVHIWFFKTMPSRIGNVLGMTSADLERVIYYEEYVVINPGQTDLERKQLLNDTEY
REAQEKWGRDSFVAKMGGEAIRDLLASEDLQTQLVELKDKLRKTKSQQARMKLAKRLKIIESFVSSDNKPEWMIMSCVPV
IPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILKLKTPDVIVRNEKRMLQEAVDALFDNGRHGHPVMGAGNRPL
KSLSEMLKGKQGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKLMALELFEPFIVKRLKDQGYVYTIRSAKKMIQRH
APEVWDVLEDIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRIHPLVCSAFNADFDGDQMAVYVPLSIEAQLEAKLLM
MAPDNIFLPSSGKPVAVPSQDMTLGLYYLMLDPLYIRENHELKTRVFRDSEEVLLALQASGSYNWYEEGSKSPNGENRSD
YLRGIRIHEKIKLRTENGIIETTPGRVVFNTIVPKELGFQNYSLPKKKMGELVMQCYKKAGLEATVRFLDNLKSIGFAEA
TKSALSMGVCDVKIPTIKQKILHDAHERVAVVRKQYEDGIITEGERYSKTISIWTEVSDVLSEELFKLISEVKDSTMNPL
YLMMDSGARGNKSQIRQLGALRGLMAKPSGDIIESPITSNFREGLSVIEFSISSHGARKGLADTALKTADSGYLTRRLVD
VAQDVIITEDDCGTLNGIDVSAIKQGQEELLPLKDRIFGRTVCEDIYQPGDSTKLLAKSGDTLTVLQAEAIDDSGIESIR
IRSVLTCETRRGVCAKCYGINLANSRSISMGEAVGIIAAQSIGEPGTQLTMRTFHLGGIASAGLTPEIVADDNGILVYTD
LRTVKTDEGNWVALNKNGRLNIVKDEGRTLDEYKKLLSTKSIEPLQAFNVELGTKILLEEGTKVKPGTRVAEWEQHNIPI
ICDRPGYVRYEDLVEGLSTERDVNKQTGQAELIVKQHRGELHPQVAIYADQACEDLVGTYPLPAGAIISVEEGEFATAGK
MLARLPRSAIKTKDITGGLPRVAELFEARKPKDSAEIAKIDGVVDFRGVQKNKRIVVVRDEMTGMEEEHLISHTKHLIIQ
RGDHVVKGQQLTDGLVIPHEILDICGVRELQKYLVNQVQEVYRLQGVDINDKHIEIIVRQMLKKVRVIDPGDTSLLYGEE
VDKKEFEVENQKVSQEGGKAAQATPVLLGITKASLSTESFISAASFQDTTRVLTEAACAGKTDYLVGFKENVIMGHIIPG
GTGFDRHKRVKMFVDSEQEQGLEFNFAD

Sequences:

>Translated_1388_residues
MSERNQQDGQFDKLTIKIASDDVIRNEWSRGEIKKPETINYRTFKPEKGGLFCEKIFGPTRDWECACGKYKKIKHKGIVC
DRCGVEVTLSKVRRERMAHIDLAVPVVHIWFFKTMPSRIGNVLGMTSADLERVIYYEEYVVINPGQTDLERKQLLNDTEY
REAQEKWGRDSFVAKMGGEAIRDLLASEDLQTQLVELKDKLRKTKSQQARMKLAKRLKIIESFVSSDNKPEWMIMSCVPV
IPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILKLKTPDVIVRNEKRMLQEAVDALFDNGRHGHPVMGAGNRPL
KSLSEMLKGKQGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKLMALELFEPFIVKRLKDQGYVYTIRSAKKMIQRH
APEVWDVLEDIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRIHPLVCSAFNADFDGDQMAVYVPLSIEAQLEAKLLM
MAPDNIFLPSSGKPVAVPSQDMTLGLYYLMLDPLYIRENHELKTRVFRDSEEVLLALQASGSYNWYEEGSKSPNGENRSD
YLRGIRIHEKIKLRTENGIIETTPGRVVFNTIVPKELGFQNYSLPKKKMGELVMQCYKKAGLEATVRFLDNLKSIGFAEA
TKSALSMGVCDVKIPTIKQKILHDAHERVAVVRKQYEDGIITEGERYSKTISIWTEVSDVLSEELFKLISEVKDSTMNPL
YLMMDSGARGNKSQIRQLGALRGLMAKPSGDIIESPITSNFREGLSVIEFSISSHGARKGLADTALKTADSGYLTRRLVD
VAQDVIITEDDCGTLNGIDVSAIKQGQEELLPLKDRIFGRTVCEDIYQPGDSTKLLAKSGDTLTVLQAEAIDDSGIESIR
IRSVLTCETRRGVCAKCYGINLANSRSISMGEAVGIIAAQSIGEPGTQLTMRTFHLGGIASAGLTPEIVADDNGILVYTD
LRTVKTDEGNWVALNKNGRLNIVKDEGRTLDEYKKLLSTKSIEPLQAFNVELGTKILLEEGTKVKPGTRVAEWEQHNIPI
ICDRPGYVRYEDLVEGLSTERDVNKQTGQAELIVKQHRGELHPQVAIYADQACEDLVGTYPLPAGAIISVEEGEFATAGK
MLARLPRSAIKTKDITGGLPRVAELFEARKPKDSAEIAKIDGVVDFRGVQKNKRIVVVRDEMTGMEEEHLISHTKHLIIQ
RGDHVVKGQQLTDGLVIPHEILDICGVRELQKYLVNQVQEVYRLQGVDINDKHIEIIVRQMLKKVRVIDPGDTSLLYGEE
VDKKEFEVENQKVSQEGGKAAQATPVLLGITKASLSTESFISAASFQDTTRVLTEAACAGKTDYLVGFKENVIMGHIIPG
GTGFDRHKRVKMFVDSEQEQGLEFNFAD
>Mature_1387_residues
SERNQQDGQFDKLTIKIASDDVIRNEWSRGEIKKPETINYRTFKPEKGGLFCEKIFGPTRDWECACGKYKKIKHKGIVCD
RCGVEVTLSKVRRERMAHIDLAVPVVHIWFFKTMPSRIGNVLGMTSADLERVIYYEEYVVINPGQTDLERKQLLNDTEYR
EAQEKWGRDSFVAKMGGEAIRDLLASEDLQTQLVELKDKLRKTKSQQARMKLAKRLKIIESFVSSDNKPEWMIMSCVPVI
PPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILKLKTPDVIVRNEKRMLQEAVDALFDNGRHGHPVMGAGNRPLK
SLSEMLKGKQGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKLMALELFEPFIVKRLKDQGYVYTIRSAKKMIQRHA
PEVWDVLEDIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRIHPLVCSAFNADFDGDQMAVYVPLSIEAQLEAKLLMM
APDNIFLPSSGKPVAVPSQDMTLGLYYLMLDPLYIRENHELKTRVFRDSEEVLLALQASGSYNWYEEGSKSPNGENRSDY
LRGIRIHEKIKLRTENGIIETTPGRVVFNTIVPKELGFQNYSLPKKKMGELVMQCYKKAGLEATVRFLDNLKSIGFAEAT
KSALSMGVCDVKIPTIKQKILHDAHERVAVVRKQYEDGIITEGERYSKTISIWTEVSDVLSEELFKLISEVKDSTMNPLY
LMMDSGARGNKSQIRQLGALRGLMAKPSGDIIESPITSNFREGLSVIEFSISSHGARKGLADTALKTADSGYLTRRLVDV
AQDVIITEDDCGTLNGIDVSAIKQGQEELLPLKDRIFGRTVCEDIYQPGDSTKLLAKSGDTLTVLQAEAIDDSGIESIRI
RSVLTCETRRGVCAKCYGINLANSRSISMGEAVGIIAAQSIGEPGTQLTMRTFHLGGIASAGLTPEIVADDNGILVYTDL
RTVKTDEGNWVALNKNGRLNIVKDEGRTLDEYKKLLSTKSIEPLQAFNVELGTKILLEEGTKVKPGTRVAEWEQHNIPII
CDRPGYVRYEDLVEGLSTERDVNKQTGQAELIVKQHRGELHPQVAIYADQACEDLVGTYPLPAGAIISVEEGEFATAGKM
LARLPRSAIKTKDITGGLPRVAELFEARKPKDSAEIAKIDGVVDFRGVQKNKRIVVVRDEMTGMEEEHLISHTKHLIIQR
GDHVVKGQQLTDGLVIPHEILDICGVRELQKYLVNQVQEVYRLQGVDINDKHIEIIVRQMLKKVRVIDPGDTSLLYGEEV
DKKEFEVENQKVSQEGGKAAQATPVLLGITKASLSTESFISAASFQDTTRVLTEAACAGKTDYLVGFKENVIMGHIIPGG
TGFDRHKRVKMFVDSEQEQGLEFNFAD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=652, Percent_Identity=26.3803680981595, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI39725938, Length=311, Percent_Identity=30.5466237942122, Blast_Score=121, Evalue=6e-27,
Organism=Homo sapiens, GI103471997, Length=595, Percent_Identity=26.0504201680672, Blast_Score=119, Evalue=2e-26,
Organism=Escherichia coli, GI2367335, Length=1391, Percent_Identity=50.5391804457225, Blast_Score=1378, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=649, Percent_Identity=26.040061633282, Blast_Score=186, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=487, Percent_Identity=27.1047227926078, Blast_Score=139, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6320061, Length=639, Percent_Identity=27.3865414710485, Blast_Score=193, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324690, Length=707, Percent_Identity=24.045261669024, Blast_Score=155, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6324917, Length=309, Percent_Identity=25.2427184466019, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17530899, Length=652, Percent_Identity=25.7668711656442, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281360912, Length=527, Percent_Identity=24.6679316888046, Blast_Score=123, Evalue=8e-28,
Organism=Drosophila melanogaster, GI17647875, Length=333, Percent_Identity=26.4264264264264, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_PARUW (Q6MDM0)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007604.1
- ProteinModelPortal:   Q6MDM0
- STRING:   Q6MDM0
- GeneID:   2780141
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0605
- NMPDR:   fig|264201.1.peg.605
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q6MDM0
- ProtClustDB:   PRK00566
- BioCyc:   CPRO264201:PC0605-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155299; Mature: 155168

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERNQQDGQFDKLTIKIASDDVIRNEWSRGEIKKPETINYRTFKPEKGGLFCEKIFGPT
CCCCCCCCCCEEEEEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEHHHHCCCC
RDWECACGKYKKIKHKGIVCDRCGVEVTLSKVRRERMAHIDLAVPVVHIWFFKTMPSRIG
CCCCHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLGMTSADLERVIYYEEYVVINPGQTDLERKQLLNDTEYREAQEKWGRDSFVAKMGGEA
HHHCCCHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCHHH
IRDLLASEDLQTQLVELKDKLRKTKSQQARMKLAKRLKIIESFVSSDNKPEWMIMSCVPV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
IPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILKLKTPDVIVRNEKRMLQEAVD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEECCHHHHHHHHHH
ALFDNGRHGHPVMGAGNRPLKSLSEMLKGKQGRFRQNLLGKRVDYSGRSVIIVGPELKFN
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCC
QCGLPKLMALELFEPFIVKRLKDQGYVYTIRSAKKMIQRHAPEVWDVLEDIIKGHPVLLN
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCEEEE
RAPTLHRLGIQAFEPVLIEGKAIRIHPLVCSAFNADFDGDQMAVYVPLSIEAQLEAKLLM
CCCCHHHHCHHHCCCEEECCCEEEEEEEEEECCCCCCCCCEEEEEEEEEEEEECCEEEEE
MAPDNIFLPSSGKPVAVPSQDMTLGLYYLMLDPLYIRENHELKTRVFRDSEEVLLALQAS
ECCCCEECCCCCCEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEEEECC
GSYNWYEEGSKSPNGENRSDYLRGIRIHEKIKLRTENGIIETTPGRVVFNTIVPKELGFQ
CCCCHHHCCCCCCCCCCHHHHHHCCEEEEEEEEEECCCEEEECCCCEEEEECCCHHHCCC
NYSLPKKKMGELVMQCYKKAGLEATVRFLDNLKSIGFAEATKSALSMGVCDVKIPTIKQK
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECHHHHHH
ILHDAHERVAVVRKQYEDGIITEGERYSKTISIWTEVSDVLSEELFKLISEVKDSTMNPL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YLMMDSGARGNKSQIRQLGALRGLMAKPSGDIIESPITSNFREGLSVIEFSISSHGARKG
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHCCHHEEEEEHHCCCCCCC
LADTALKTADSGYLTRRLVDVAQDVIITEDDCGTLNGIDVSAIKQGQEELLPLKDRIFGR
HHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHH
TVCEDIYQPGDSTKLLAKSGDTLTVLQAEAIDDSGIESIRIRSVLTCETRRGVCAKCYGI
HHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEEEEEC
NLANSRSISMGEAVGIIAAQSIGEPGTQLTMRTFHLGGIASAGLTPEIVADDNGILVYTD
CCCCCCCCCCCHHHHHEEHHCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCEEEEEE
LRTVKTDEGNWVALNKNGRLNIVKDEGRTLDEYKKLLSTKSIEPLQAFNVELGTKILLEE
CEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEEECC
GTKVKPGTRVAEWEQHNIPIICDRPGYVRYEDLVEGLSTERDVNKQTGQAELIVKQHRGE
CCCCCCCCCCCCHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEEHHCCC
LHPQVAIYADQACEDLVGTYPLPAGAIISVEEGEFATAGKMLARLPRSAIKTKDITGGLP
CCCEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCCH
RVAELFEARKPKDSAEIAKIDGVVDFRGVQKNKRIVVVRDEMTGMEEEHLISHTKHLIIQ
HHHHHHHHCCCCCCCCHHHHCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
RGDHVVKGQQLTDGLVIPHEILDICGVRELQKYLVNQVQEVYRLQGVDINDKHIEIIVRQ
CCCCEECCCCCCCCEECHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
MLKKVRVIDPGDTSLLYGEEVDKKEFEVENQKVSQEGGKAAQATPVLLGITKASLSTESF
HHHHCEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCHHHH
ISAASFQDTTRVLTEAACAGKTDYLVGFKENVIMGHIIPGGTGFDRHKRVKMFVDSEQEQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCCCCCEEEEEECCHHHC
GLEFNFAD
CCEEECCC
>Mature Secondary Structure 
SERNQQDGQFDKLTIKIASDDVIRNEWSRGEIKKPETINYRTFKPEKGGLFCEKIFGPT
CCCCCCCCCEEEEEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEHHHHCCCC
RDWECACGKYKKIKHKGIVCDRCGVEVTLSKVRRERMAHIDLAVPVVHIWFFKTMPSRIG
CCCCHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLGMTSADLERVIYYEEYVVINPGQTDLERKQLLNDTEYREAQEKWGRDSFVAKMGGEA
HHHCCCHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCHHH
IRDLLASEDLQTQLVELKDKLRKTKSQQARMKLAKRLKIIESFVSSDNKPEWMIMSCVPV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
IPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILKLKTPDVIVRNEKRMLQEAVD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEECCHHHHHHHHHH
ALFDNGRHGHPVMGAGNRPLKSLSEMLKGKQGRFRQNLLGKRVDYSGRSVIIVGPELKFN
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCC
QCGLPKLMALELFEPFIVKRLKDQGYVYTIRSAKKMIQRHAPEVWDVLEDIIKGHPVLLN
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCEEEE
RAPTLHRLGIQAFEPVLIEGKAIRIHPLVCSAFNADFDGDQMAVYVPLSIEAQLEAKLLM
CCCCHHHHCHHHCCCEEECCCEEEEEEEEEECCCCCCCCCEEEEEEEEEEEEECCEEEEE
MAPDNIFLPSSGKPVAVPSQDMTLGLYYLMLDPLYIRENHELKTRVFRDSEEVLLALQAS
ECCCCEECCCCCCEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEEEECC
GSYNWYEEGSKSPNGENRSDYLRGIRIHEKIKLRTENGIIETTPGRVVFNTIVPKELGFQ
CCCCHHHCCCCCCCCCCHHHHHHCCEEEEEEEEEECCCEEEECCCCEEEEECCCHHHCCC
NYSLPKKKMGELVMQCYKKAGLEATVRFLDNLKSIGFAEATKSALSMGVCDVKIPTIKQK
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECHHHHHH
ILHDAHERVAVVRKQYEDGIITEGERYSKTISIWTEVSDVLSEELFKLISEVKDSTMNPL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YLMMDSGARGNKSQIRQLGALRGLMAKPSGDIIESPITSNFREGLSVIEFSISSHGARKG
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHCCHHEEEEEHHCCCCCCC
LADTALKTADSGYLTRRLVDVAQDVIITEDDCGTLNGIDVSAIKQGQEELLPLKDRIFGR
HHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHH
TVCEDIYQPGDSTKLLAKSGDTLTVLQAEAIDDSGIESIRIRSVLTCETRRGVCAKCYGI
HHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEEEEEC
NLANSRSISMGEAVGIIAAQSIGEPGTQLTMRTFHLGGIASAGLTPEIVADDNGILVYTD
CCCCCCCCCCCHHHHHEEHHCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCEEEEEE
LRTVKTDEGNWVALNKNGRLNIVKDEGRTLDEYKKLLSTKSIEPLQAFNVELGTKILLEE
CEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEEECC
GTKVKPGTRVAEWEQHNIPIICDRPGYVRYEDLVEGLSTERDVNKQTGQAELIVKQHRGE
CCCCCCCCCCCCHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEEHHCCC
LHPQVAIYADQACEDLVGTYPLPAGAIISVEEGEFATAGKMLARLPRSAIKTKDITGGLP
CCCEEEEEEHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCCH
RVAELFEARKPKDSAEIAKIDGVVDFRGVQKNKRIVVVRDEMTGMEEEHLISHTKHLIIQ
HHHHHHHHCCCCCCCCHHHHCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
RGDHVVKGQQLTDGLVIPHEILDICGVRELQKYLVNQVQEVYRLQGVDINDKHIEIIVRQ
CCCCEECCCCCCCCEECHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
MLKKVRVIDPGDTSLLYGEEVDKKEFEVENQKVSQEGGKAAQATPVLLGITKASLSTESF
HHHHCEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCHHHH
ISAASFQDTTRVLTEAACAGKTDYLVGFKENVIMGHIIPGGTGFDRHKRVKMFVDSEQEQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCCCCCEEEEEECCHHHC
GLEFNFAD
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA