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The map label for this gene is vatB [H]

Identifier: 46446153

GI number: 46446153

Start: 652552

End: 653190

Strand: Direct

Name: vatB [H]

Synonym: pc0519

Alternate gene names: 46446153

Gene position: 652552-653190 (Clockwise)

Preceding gene: 46446152

Following gene: 46446154

Centisome position: 27.03

GC content: 37.09

Gene sequence:

>639_bases
ATGACAAGTCCAAACCCAAACTCTTTTCATCCAATTAAAGATTATGACAAATTAATTTTTCTAAAAAACTTTGTTAAAGC
CAGTAATATTTTTATCGGGGATTATACCTACTTTGATGACAGAAGATATGGTCCAGAGAGATTTGAAGAGTACAATGTTT
TGTATAACTATGACTTTTCAAAAGTAAAGCTTGTTATCGAAAAATTTTGTGCCATCGCAGCAGAAACTCGCTTTATTATG
ACGGGGGACCATAAGCTCGATGCAATTAGCACTTATCCTTTTCCCATATTTGGCTATGGTTGGGAAAGCGCTTTCAATGT
TTACGACTTACCAGTCAAGGGAGACATTATCGTCGGCAATGATGTCTGGTTCGGATATGATTCCCTAGTTATGAATGGTG
TGACGATAGGTAATGGAGCGATCATTGCAGCCAGGGCAGTGGTTGTAAAGGATGTACCTGCTTACTCAATTGTTGCAGGC
AACCCAGCTAAGGTTGTAAAAATGCGATTTGATGATAAGACTATCGACCGTTTGCAAAAAATTTCTTGGTGGAATTGGGA
GATTGAAAAAGTTAATAAAAACCTAAAACTGATCTGCCATCTTAATATAGATCACTTAGAATTAGCATCCCATGAATGA

Upstream 100 bases:

>100_bases
TACAACTATCAGCTTATAGTTACTGGTAAGTCTTATCCATTAGATGACAAACTGATCCTTTGGCTGACAAAAAACTTATA
ATACTAGGATAACTTACAAA

Downstream 100 bases:

>100_bases
CGAAGCTTCCGAATAGGAATAATTCTGAATTGATAGAGATATTATCTAAAAAAGAATTACAAAAGTAATATTCACCCATT
TTTAATCTTTAAAATAGATT

Product: streptogramin A acetyltransferase

Products: CoA; acetylmaltose [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTSPNPNSFHPIKDYDKLIFLKNFVKASNIFIGDYTYFDDRRYGPERFEEYNVLYNYDFSKVKLVIEKFCAIAAETRFIM
TGDHKLDAISTYPFPIFGYGWESAFNVYDLPVKGDIIVGNDVWFGYDSLVMNGVTIGNGAIIAARAVVVKDVPAYSIVAG
NPAKVVKMRFDDKTIDRLQKISWWNWEIEKVNKNLKLICHLNIDHLELASHE

Sequences:

>Translated_212_residues
MTSPNPNSFHPIKDYDKLIFLKNFVKASNIFIGDYTYFDDRRYGPERFEEYNVLYNYDFSKVKLVIEKFCAIAAETRFIM
TGDHKLDAISTYPFPIFGYGWESAFNVYDLPVKGDIIVGNDVWFGYDSLVMNGVTIGNGAIIAARAVVVKDVPAYSIVAG
NPAKVVKMRFDDKTIDRLQKISWWNWEIEKVNKNLKLICHLNIDHLELASHE
>Mature_211_residues
TSPNPNSFHPIKDYDKLIFLKNFVKASNIFIGDYTYFDDRRYGPERFEEYNVLYNYDFSKVKLVIEKFCAIAAETRFIMT
GDHKLDAISTYPFPIFGYGWESAFNVYDLPVKGDIIVGNDVWFGYDSLVMNGVTIGNGAIIAARAVVVKDVPAYSIVAGN
PAKVVKMRFDDKTIDRLQKISWWNWEIEKVNKNLKLICHLNIDHLELASHE

Specific function: Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.79 [C]

Molecular weight: Translated: 24395; Mature: 24264

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPNPNSFHPIKDYDKLIFLKNFVKASNIFIGDYTYFDDRRYGPERFEEYNVLYNYDFS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECEEEECCCCCCHHHHHHEEEEEECCHH
KVKLVIEKFCAIAAETRFIMTGDHKLDAISTYPFPIFGYGWESAFNVYDLPVKGDIIVGN
HHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCEEEECCCCCCCEEEECCCCCCEEECC
DVWFGYDSLVMNGVTIGNGAIIAARAVVVKDVPAYSIVAGNPAKVVKMRFDDKTIDRLQK
CEEECHHHHHCCCEEECCCEEEEEEEEEEECCCCEEEEECCCEEEEEEECCCHHHHHHHH
ISWWNWEIEKVNKNLKLICHLNIDHLELASHE
CCCCCEEEEECCCCEEEEEEECCCEEEECCCC
>Mature Secondary Structure 
TSPNPNSFHPIKDYDKLIFLKNFVKASNIFIGDYTYFDDRRYGPERFEEYNVLYNYDFS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECEEEECCCCCCHHHHHHEEEEEECCHH
KVKLVIEKFCAIAAETRFIMTGDHKLDAISTYPFPIFGYGWESAFNVYDLPVKGDIIVGN
HHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCEEEECCCCCCCEEEECCCCCCEEECC
DVWFGYDSLVMNGVTIGNGAIIAARAVVVKDVPAYSIVAGNPAKVVKMRFDDKTIDRLQK
CEEECHHHHHCCCEEECCCEEEEEEEEEEECCCCEEEEECCCEEEEEEECCCHHHHHHHH
ISWWNWEIEKVNKNLKLICHLNIDHLELASHE
CCCCCEEEEECCCCEEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: 0.20 {glucose} 0.11 {maltose}

Km value (mM): 0.018 {acetyl-CoA}} 62 {glucose}} 40 {triethanolamine}} 90 {maltose}} [C]

Substrates: Acetyl-CoA; maltose [C]

Specific reaction: Acetyl-CoA + maltose = CoA + acetylmaltose [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344533; 3149758 [H]