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The map label for this gene is mraY

Identifier: 45657729

GI number: 45657729

Start: 2261342

End: 2262448

Strand: Reverse

Name: mraY

Synonym: LIC11866

Alternate gene names: 45657729

Gene position: 2262448-2261342 (Counterclockwise)

Preceding gene: 45657730

Following gene: 45657728

Centisome position: 52.9

GC content: 36.5

Gene sequence:

>1107_bases
ATGTTTTATTATCTTTATGATCTTTATTTCAATCATCTAGACTCGCTTCGAATTTTCAGTTATGTTACCTTTAGAGCTCT
GATGGCCGGTTTGACTTCTATGTTAGTCACGTTTTGGTTCGGACATAAGATCATCGACTTTTTATACGGATTAAAATTTA
GAGAATCCGTTCGAGATGACGGTCCCAAGTCTCACGAAATTAAAAAAGGAACACCTACGATGGGAGGACTTTTGATCATA
GGTTCTCTTTTGATTTCAGTTTTACTCTGGGGAAATTTAAAAAATCCGAATGTGATTTTACTTTCCGTATTCTCCCTTTC
TTTTTCTGTGTTGGGTTTTGCGGACGATTATATGAAGTCAGTAAAAAAAATCAAAGGTGGAATGAGGGCAAGAACTAAGT
TTATACTTTCAATTTTGATCTCTTTTATTTTTTGTATATTATTTTTTTATTATACAGGAACGACTGGTCAAACTGGTAAG
ATCTCTTTTCAACTTACTGATTTATTTTTTCCTTTTATCAAAGGACCCGTAATTGCGTTAGGCATAATTGCTATTCCTTT
TTCAATTCTTGTCATTATTGGTTCTTCTCACGCTGTGAATTTGACGGACGGACTTGATGGTCTTGCAACGGGAACCGTTT
TGATTTCAGTGATGACTTTAGGAGTTATTGCTTATTTTTCCGGAACTCCTATTGTAGCGAATTACTTGAACATTCCTTAT
CTTCCGGGGGCACACGAATATTCAGTGTTTCTTTCCGCACTCACAGGTGCACTTTTTGGTTTTTTATGGTTCAATGCACA
CCCCGCTCAAGTGTTTATGGGTGATACCGGTTCTTTGTTTTTAGGAGCAACACTCGGGATGATAGTGATTCTTTTGAAGA
AGGAAATTTTACTTTTAATCTTGGGAGCGATTTTCGTGAGTGAGGCTCTTTCGGTGATACTTCAAGTAGGTTCGTTTAAA
CTGACCGGAAAAAGAATCTTTAAGATGGCTCCGCTTCATCATCATTTTGAGTTAGGTGGATTGAAGGAAACTAAGATAGT
GATTCGTTTTTGGATCATTGCAGTCATTTTGGCGATTATATCTCTCTCGACTTTGAAAATTCAATGA

Upstream 100 bases:

>100_bases
TCAGTGACGTGGAAGAAGTTCAAAAAGCGTTCGGGCTTTTTTAGAAATTTTCCGATACAAAAAAAGAATACTCCGTTTTT
TTGAAAACAGGGCAGGAAAA

Downstream 100 bases:

>100_bases
TCAATTTTATCATAAGAAAGTGGAGAGAGTTTTGGCTTCCCGGAAAAAATTCCTTAGACGTTCTTTTGATCGTGACGATT
TTTATTCTCTTATTTACCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDDGPKSHEIKKGTPTMGGLLII
GSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKSVKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGK
ISFQLTDLFFPFIKGPVIALGIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPY
LPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGSFK
LTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAIISLSTLKIQ

Sequences:

>Translated_368_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDDGPKSHEIKKGTPTMGGLLII
GSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKSVKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGK
ISFQLTDLFFPFIKGPVIALGIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPY
LPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGSFK
LTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAIISLSTLKIQ
>Mature_368_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDDGPKSHEIKKGTPTMGGLLII
GSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKSVKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGK
ISFQLTDLFFPFIKGPVIALGIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPY
LPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGSFK
LTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAIISLSTLKIQ

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=368, Percent_Identity=45.3804347826087, Blast_Score=308, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40645; Mature: 40645

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS01347 MRAY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GPKSHEIKKGTPTMGGLLIIGSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
VKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGKISFQLTDLFFPFIKGPVIAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCHHHHH
GIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPY
HHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
LPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LGAIFVSEALSVILQVGSFKLTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAII
HHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SLSTLKIQ
HHHHHCCC
>Mature Secondary Structure
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GPKSHEIKKGTPTMGGLLIIGSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
VKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGKISFQLTDLFFPFIKGPVIAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCHHHHH
GIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPY
HHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
LPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LGAIFVSEALSVILQVGSFKLTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAII
HHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SLSTLKIQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA