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The map label for this gene is dsbA

Identifier: 45657501

GI number: 45657501

Start: 1994379

End: 1994876

Strand: Direct

Name: dsbA

Synonym: LIC11629

Alternate gene names: 45657501

Gene position: 1994379-1994876 (Clockwise)

Preceding gene: 45657499

Following gene: 45657502

Centisome position: 46.63

GC content: 33.33

Gene sequence:

>498_bases
ATGTGGAATTTGCGTTTAATTTTTCTATTCGTTTTTTTTCTGCTATTTTCTTGTAGTCTTTCTAGGGAAGAATCGATCCT
TTATCAGCTTTCTCTTTACGATTTGGATAAAAATTCTGTTTCTTTGAAAGAATATAAAGGAAAAGTTTTGCTTTTAGATA
TTTGGGCTTCTTGGTGTGAACCTTGTAAAGATGCGGTTCCTGTTTTGGAAAAACTTTCTAAAGACTTAAATGGCAAAAAT
GGGGTTTTGTTAGGAATCAATACGGAGCCCGAACTTTCCAAAGAAGAACATTTAAAAGCAGCTAAAGAATTTGGAATGAC
TTATCCGTTTTTTGTGGATCGCGATTTTACTTTGATTAACCAATATAAGGTAGAAGGTCAGCCTGCTTTGATTGTTTTTA
GTCAGTCCGGAACTCTTCTTAAAATTCAATACGGCATTCGGGAAAAAGATTATCCTAAACTTAGAGCTAATTTTTCAAAT
TGGTTTTCTGCACCTTAA

Upstream 100 bases:

>100_bases
AACAGGATTCACTGGAATGATTCCAATTTTTGCGAATGGATTTTGCTGAAAAGATTTTTTCCTTTTACTTTCTATTCGTT
TTTTTGAATAAGATGAAATC

Downstream 100 bases:

>100_bases
TATATAAAATGAATTTTTCGTAAAACAACGATTTTATGTATATTTAATTTGAGAATGCAACTGTAAAATCTAGATTTGTA
AGAATTCCCACACCTAACTT

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MWNLRLIFLFVFFLLFSCSLSREESILYQLSLYDLDKNSVSLKEYKGKVLLLDIWASWCEPCKDAVPVLEKLSKDLNGKN
GVLLGINTEPELSKEEHLKAAKEFGMTYPFFVDRDFTLINQYKVEGQPALIVFSQSGTLLKIQYGIREKDYPKLRANFSN
WFSAP

Sequences:

>Translated_165_residues
MWNLRLIFLFVFFLLFSCSLSREESILYQLSLYDLDKNSVSLKEYKGKVLLLDIWASWCEPCKDAVPVLEKLSKDLNGKN
GVLLGINTEPELSKEEHLKAAKEFGMTYPFFVDRDFTLINQYKVEGQPALIVFSQSGTLLKIQYGIREKDYPKLRANFSN
WFSAP
>Mature_165_residues
MWNLRLIFLFVFFLLFSCSLSREESILYQLSLYDLDKNSVSLKEYKGKVLLLDIWASWCEPCKDAVPVLEKLSKDLNGKN
GVLLGINTEPELSKEEHLKAAKEFGMTYPFFVDRDFTLINQYKVEGQPALIVFSQSGTLLKIQYGIREKDYPKLRANFSN
WFSAP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19104; Mature: 19104

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNLRLIFLFVFFLLFSCSLSREESILYQLSLYDLDKNSVSLKEYKGKVLLLDIWASWCE
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEHHHHCCCEEEEEHHHHHHH
PCKDAVPVLEKLSKDLNGKNGVLLGINTEPELSKEEHLKAAKEFGMTYPFFVDRDFTLIN
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEEE
QYKVEGQPALIVFSQSGTLLKIQYGIREKDYPKLRANFSNWFSAP
EEEECCCCEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MWNLRLIFLFVFFLLFSCSLSREESILYQLSLYDLDKNSVSLKEYKGKVLLLDIWASWCE
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEHHHHCCCEEEEEHHHHHHH
PCKDAVPVLEKLSKDLNGKNGVLLGINTEPELSKEEHLKAAKEFGMTYPFFVDRDFTLIN
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEEE
QYKVEGQPALIVFSQSGTLLKIQYGIREKDYPKLRANFSNWFSAP
EEEECCCCEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]