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The map label for this gene is mcpB [H]

Identifier: 45657099

GI number: 45657099

Start: 1497838

End: 1499562

Strand: Direct

Name: mcpB [H]

Synonym: LIC11216

Alternate gene names: 45657099

Gene position: 1497838-1499562 (Clockwise)

Preceding gene: 45657097

Following gene: 45657100

Centisome position: 35.02

GC content: 39.19

Gene sequence:

>1725_bases
ATGAAAACTATATATATATTCATGCAGAGACTGGGAATACGAACAAAACTAATGCTTCTATTTGGATCGGTACTAATACC
GATTGCCATCTTAGTTGCATTGGCTTTAACGAACACTAAAGATAGGATTGAGGATATCGAAACAATTTACGAGGATCGTG
TAATTCCTCTGAAACAATTGAAGAAAATATCCGATCTCTATGCAATTTTTATCGTAGACTGTGTTCATAAAGTAAGAAGT
GGCACTTTCACACCGGAAGAAGGAGTCGTTAACCTTGATAAGGCGACTTCAGGAATTCAGGAAGAATGGACCGCTTATAT
GGGAACTCGTCTAGCTCCGGAAGAAGAGGCAATTATCCGAGATTTGACTCCTCTTTTTGATGCTTCTAACGCCGCCGTAA
CAGAAGCCAGAGGACTGATGGTTGCTAAAAACTTTCAAGAATTAGGAGTTTTTGCAGACAATCGTTTGTATCCTAGAATT
GATCCAGTGACAGATAAAATCGAAGAACTGATTCAACTTCAACTTAAGATTACGGATACGATCTACATCAGAGCGGAAAA
GGAATTCACCTATAGTTGGTTTTCGTTTATTCTTCTTTCTGGCATTACGTTGACCTATATTTTTTTGATTGCTGTGTTTT
ACTCAATTCGATTAGTCAAAGGATTAAATACAGTAAGTAGCGCAGTCAAAAACGCGGACTTTTCTCATCCTGTAGAAGTA
GAGGAAGACTCAAATAAAAAAGACGAACTTTATCTTTTGCATCTGGCGTTTCGTTTATTCCAGATCAAAGTCAGAGAAAT
GTTGAATACGATTTTGAATTTTTCCGAAAGTATTCTGGCGGCTTCTGAACAACTTTCTAAGTCTGCAGATCATCTTTCGG
CGAACGCACAATCCGAATCGGCTTCGATTGAACAGATATCCGCATCTGTGGAAGAGATTAGTTCCGGAATGGAATATGTA
AATCGAAACGCAGAATCTCAATACGCTTTGATTTCTTCGTTTAACGGAGAAATGCGAGAGCTGGAAGGGATGATTAACAA
GGTAGGAGATGCGGTAAAAAATTCTTTGGAAAAAATTTCGGATATGTATCTGAAAACCGATTCTGGTAAAAAAACGATGG
GAGATCTTTCCGATAGTATGGAAAAGATCGAAAGTAGTTCTGTCGAGATGCAGTCCATTACTGCCATCATCAAAGAAATA
TCAGAAAAAGTGAATTTACTTGCACTCAATGCTGCAATCGAGGCGGCAAGAGCAGGAGAACACGGTAGAGGTTTTGCCGT
AGTGGCGAGTGAAATTACAAGGCTTGCGGAACAAACGGATTCTAGCGCGATGACAATCGAAGAGCTAATTAAAACGAGTA
ACGCTGAAATAGAAACGGGTAGAAAGATCGTGGAAAATTCTGTTCGTGTTTATGCTGAAATTTTAAGTGGTCTGGAACAT
CTGAAAGAATCTTCTAATCAAATTGTAGCTACGATGGCGCTTCAGCAGGAGAAAAAGGACAAGATTCGTTCTGGAGTGGA
TCAAGTGTATGAGAAGTCAGAAGACATACGCAGTTCCGTTAAAGAACAAAAAATTGCAGTTTCGGAAACGGCAAACGCGG
TTTCTAATATTTCCATTACGGTTCAAAACAGCGCCGCAAACTCGGAAGAAATCGCAGGAAGTGCAATTGGTCTTTTGCAG
ATTGCAAAAAAACTTCAAGATACGATGAATTTTCTGAAGAGTTAA

Upstream 100 bases:

>100_bases
GTTTACTTACTTTATAAATTTGTACTCTTAAAAAGAGATTCATTTTTTAAAAAACTTGACTGAGTATATATCAAGGCAAC
TATGAAACGCTTTAAATTCT

Downstream 100 bases:

>100_bases
TTTTTCTACAAGAATACGTTACGAACTAGTAACTCTGTATCTACGAATTATGAATCGTTTTTACAGAGTTATCTTTCTTT
TGAGTTTTAAACTTATAGAT

Product: methyl-accepting chemotaxis transducer transmembrane protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MKTIYIFMQRLGIRTKLMLLFGSVLIPIAILVALALTNTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVVNLDKATSGIQEEWTAYMGTRLAPEEEAIIRDLTPLFDASNAAVTEARGLMVAKNFQELGVFADNRLYPRI
DPVTDKIEELIQLQLKITDTIYIRAEKEFTYSWFSFILLSGITLTYIFLIAVFYSIRLVKGLNTVSSAVKNADFSHPVEV
EEDSNKKDELYLLHLAFRLFQIKVREMLNTILNFSESILAASEQLSKSADHLSANAQSESASIEQISASVEEISSGMEYV
NRNAESQYALISSFNGEMRELEGMINKVGDAVKNSLEKISDMYLKTDSGKKTMGDLSDSMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVRVYAEILSGLEH
LKESSNQIVATMALQQEKKDKIRSGVDQVYEKSEDIRSSVKEQKIAVSETANAVSNISITVQNSAANSEEIAGSAIGLLQ
IAKKLQDTMNFLKS

Sequences:

>Translated_574_residues
MKTIYIFMQRLGIRTKLMLLFGSVLIPIAILVALALTNTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVVNLDKATSGIQEEWTAYMGTRLAPEEEAIIRDLTPLFDASNAAVTEARGLMVAKNFQELGVFADNRLYPRI
DPVTDKIEELIQLQLKITDTIYIRAEKEFTYSWFSFILLSGITLTYIFLIAVFYSIRLVKGLNTVSSAVKNADFSHPVEV
EEDSNKKDELYLLHLAFRLFQIKVREMLNTILNFSESILAASEQLSKSADHLSANAQSESASIEQISASVEEISSGMEYV
NRNAESQYALISSFNGEMRELEGMINKVGDAVKNSLEKISDMYLKTDSGKKTMGDLSDSMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVRVYAEILSGLEH
LKESSNQIVATMALQQEKKDKIRSGVDQVYEKSEDIRSSVKEQKIAVSETANAVSNISITVQNSAANSEEIAGSAIGLLQ
IAKKLQDTMNFLKS
>Mature_574_residues
MKTIYIFMQRLGIRTKLMLLFGSVLIPIAILVALALTNTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVVNLDKATSGIQEEWTAYMGTRLAPEEEAIIRDLTPLFDASNAAVTEARGLMVAKNFQELGVFADNRLYPRI
DPVTDKIEELIQLQLKITDTIYIRAEKEFTYSWFSFILLSGITLTYIFLIAVFYSIRLVKGLNTVSSAVKNADFSHPVEV
EEDSNKKDELYLLHLAFRLFQIKVREMLNTILNFSESILAASEQLSKSADHLSANAQSESASIEQISASVEEISSGMEYV
NRNAESQYALISSFNGEMRELEGMINKVGDAVKNSLEKISDMYLKTDSGKKTMGDLSDSMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVRVYAEILSGLEH
LKESSNQIVATMALQQEKKDKIRSGVDQVYEKSEDIRSSVKEQKIAVSETANAVSNISITVQNSAANSEEIAGSAIGLLQ
IAKKLQDTMNFLKS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=330, Percent_Identity=26.6666666666667, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=23.3983286908078, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789453, Length=412, Percent_Identity=25.9708737864078, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1787690, Length=270, Percent_Identity=28.1481481481481, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=204, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 63731; Mature: 63731

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIYIFMQRLGIRTKLMLLFGSVLIPIAILVALALTNTKDRIEDIETIYEDRVIPLKQL
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
KKISDLYAIFIVDCVHKVRSGTFTPEEGVVNLDKATSGIQEEWTAYMGTRLAPEEEAIIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCHHHHHHHHHCCCCCCHHHHHHH
DLTPLFDASNAAVTEARGLMVAKNFQELGVFADNRLYPRIDPVTDKIEELIQLQLKITDT
HHHHHHCCCCCHHHHHCCHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEE
IYIRAEKEFTYSWFSFILLSGITLTYIFLIAVFYSIRLVKGLNTVSSAVKNADFSHPVEV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EEDSNKKDELYLLHLAFRLFQIKVREMLNTILNFSESILAASEQLSKSADHLSANAQSES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASIEQISASVEEISSGMEYVNRNAESQYALISSFNGEMRELEGMINKVGDAVKNSLEKIS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMYLKTDSGKKTMGDLSDSMEKIESSSVEMQSITAIIKEISEKVNLLALNAAIEAARAGE
HHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVRVYAEILSGLEH
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKESSNQIVATMALQQEKKDKIRSGVDQVYEKSEDIRSSVKEQKIAVSETANAVSNISIT
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
VQNSAANSEEIAGSAIGLLQIAKKLQDTMNFLKS
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTIYIFMQRLGIRTKLMLLFGSVLIPIAILVALALTNTKDRIEDIETIYEDRVIPLKQL
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
KKISDLYAIFIVDCVHKVRSGTFTPEEGVVNLDKATSGIQEEWTAYMGTRLAPEEEAIIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCHHHHHHHHHCCCCCCHHHHHHH
DLTPLFDASNAAVTEARGLMVAKNFQELGVFADNRLYPRIDPVTDKIEELIQLQLKITDT
HHHHHHCCCCCHHHHHCCHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEE
IYIRAEKEFTYSWFSFILLSGITLTYIFLIAVFYSIRLVKGLNTVSSAVKNADFSHPVEV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EEDSNKKDELYLLHLAFRLFQIKVREMLNTILNFSESILAASEQLSKSADHLSANAQSES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASIEQISASVEEISSGMEYVNRNAESQYALISSFNGEMRELEGMINKVGDAVKNSLEKIS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMYLKTDSGKKTMGDLSDSMEKIESSSVEMQSITAIIKEISEKVNLLALNAAIEAARAGE
HHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVRVYAEILSGLEH
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKESSNQIVATMALQQEKKDKIRSGVDQVYEKSEDIRSSVKEQKIAVSETANAVSNISIT
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
VQNSAANSEEIAGSAIGLLQIAKKLQDTMNFLKS
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]