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The map label for this gene is 45657073

Identifier: 45657073

GI number: 45657073

Start: 1464048

End: 1466030

Strand: Direct

Name: 45657073

Synonym: LIC11189

Alternate gene names: NA

Gene position: 1464048-1466030 (Clockwise)

Preceding gene: 45657072

Following gene: 45657075

Centisome position: 34.23

GC content: 34.14

Gene sequence:

>1983_bases
ATGAAACCGAAATTCCCTAAATACATTGTCACCGACCTAGATTCGATCGTTAAAAGGTTAGGTCCAATTATTAGTCGTTT
AGAAATTGAATTTTTAGATTTTAAGGAATTTTTTCAGTCTGAGCTATTTCGAAATTCTAGTGGGTTTTTGAATGTTATTT
TTTATTTAACCGTTTCCGATCTCAAAAAAACTCAAAAAGAAATTCATCAACAATTTCAAAGAAATCCTCTGATCTTAAGT
CGTTTTATTTTAAACGAAAATTTAGATTACGTTCATTCGGAAGATTTAAAAATCGAAGAGGAATTAATTTTTTCAGTTTT
ACCGGAATCTTCTTCAGATATGGTTTTTAACAAAACCTTTTTGAATGCGTTCACCCAACTTCAAATGATTACAGATCAGT
TTGATCTTCAACACAAGGTGAATACTACTAAGTATGAAATTTCTAAACTGACTAGAGTAGGGATTAGCCTTGCCGATGAA
AAAGACATCAATAAACTTCTTCGAGAAATTATTTTTAGCGCTAGGGAAATTGCGATCGCCGATTCGGGTTCTTTATATCT
CGTTGAAAAAGATGAACTAGGTTTGGTTCGTAATCTTAGGTTTAAAATTTCTTCTATGGATATTGATACGGAAGAATTTT
TACTTCCGATTAATAAATCCAGTGTTGCGGGTTATGTTGCAGCAACCGGAAAAATTTTAAATATTCCAGACGTTTACAAT
TTACCGGAAGATTCGGAATATAAATTCAACAGAAATTTCGATGTTCTTTCTAATTATCATACTAAGTCCATGCTCGTTGT
TCCTATGAAAAATCATAGAAACGAAGTTGTAGGTGTCATTCAACTTATTAATAAGAAGAGAAACTTTAATCAAAAACTGA
CTCTTGAACAAATGAGAGGGAATGACGTATTTCCTTTTGACGATTATTCTGCTCAACTTGTGATGGGTGTGGCGGGACAG
GCTGCGGTTGCGATTCAAAATAATCATCTTTTACAGGAGATCGAAGCTCTTTTCGAAGGTTTTGTGACTGCGTCCGTAAA
TGCGATCGAATCCAGAGATCCAACAACAAGTGGGCATTCATTTCGTGTAGCCGTACTTACGGTTGGTTTGGCTGAAACGG
TGGATTTGATCAGAGAAGGTAAATATAAAAATACCAAGTTTTCGAAAGAACAGATCAAAGAAATACGTTATGCTTCATTG
CTTCATGATTTTGGAAAAGTGGGGGTTCGAGAAAAGGTTTTGGTCAAATCCAAAAAGCTGGAAGACTATGAACTTGAGTT
GATCCGTTGGAGATTTGAATATATTAAAAAAGACATAGAATCTAGAATTCTTCAGAAAAAGACGGATTATTTAAAAAAAC
ACGGGGCGGTAGGTTTTGCCGATTATGAGACTTCTCTGGAATTTGAACTTAAGGTAGAATATCAAAAGTTAGATCAAATG
TTTCAGATCGTTGTCGATTCCAATGAGCCTTCTATATTAGAAGAATCTAATTTTCAAAAATTGGAAGAAATTGCAAAAGT
AAATTATTCTACTACAGGTGGAGAAAAGTTGTCTTTGATTTCTCCTTACGAATTTGGTTTTTTGACGATCAAAAAAGGAT
CTTTGGATTTTGCTGAAAGAAAAGAAATTGAATCTCATGTGGAACATACGTTTCAGTTTTTAAGTAAAATTCCTTGGACT
GGAGATCTAAAAATGGTTCCTTCCATTGCACATGCGCATCATGAAAAATTGGATGGGACCGGTTATCCTAGAGGACTTAC
AGCTGATTCTATTCCAATTCAATCTAAAATTATGGCGATCTCCGATATATTTGATGCACTTACGGATAAAGATCGTCCCT
ATAAAAGAGCCGTTCCTATAGAAAGAGCTCTAGATATTTTACAAATGGAAGCAAGGGAAAATCACGTAGATCAAGATCTT
CTCAAAATTTTTATTGAAGGAAAGGTTTACGATAAATTGTATTACTCTGGTTACCTTCGTTAG

Upstream 100 bases:

>100_bases
TTTTCATTTCAAGTTATAGATTTCGTTTCCTTTTTGCAAAGTTAGGAAAAAAATTATCTTTCCCATATATTTCCTGTACG
GTTTCATTGATTCCTGATCA

Downstream 100 bases:

>100_bases
GTGTATTTTTCTCTGTTTTGTTGCAATCCACGATTTTAGACGATTCTACTAACAAATAAATTTTTCGATAATTTAAACTT
TAATAATATAAGTTCTCCAT

Product: hypothetical protein

Products: nucleoside 5'-phosphate

Alternate protein names: Metal-Dependent Phosphohydrolase; Response Regulator; Chemotaxis Sensory Transducer Family Protein; HAMP Domain Protein; GAF Domain-Containing Protein; HD-GYP Domain-Containing Protein; Methyl-Accepting Chemotaxis Protein; PAS/PAC Sensor Protein; HD-Domain-Containing Protein; Two-Component Response Regulator; GAF Domain/HD Domain-Containing Protein; Response Regulator Receiver; Chemotactic Transducer-Related Protein; Two-Component System Response Regulator; Response Regulator Receiver Protein; Sensor Histidine Kinase; Adenylate/Guanylate Cyclase; Response Regulator CheB; Serine Phosphatase; Pas/Pac Sensor Protein; Response Regulator-Like Protein; PAS Sensor Protein; ABC-Type Amino Acid Transport Signal Transduction Systems; Metal Dependent Phosphohydrolase With Gaf Sensor; HD-GYP/GAF Domain-Containing Protein; Hamp Domain/Gaf Domain/Hd Domain Protein; 3 5'-Cyclic-Nucleotide Phosphodiesterase; Diguanylate Cyclase With PAS/PAC Sensor; GAF Domain/HD Domain Protein; HDIG Domain-Containing Protein; Metal-Dependent Phosphohydrolase HD Subdomain; GAF Containing Protein; Signal Transduction Response Regulator; Diguanylate Cyclase; Replicative DNA Helicase; GAF Domain Protein; Two-Component Regulatory System Response Regulator; Sensory Box-Containing Diguanylate Cyclase; Sensor Histidine Kinase/GAF Domain-Containing Protein; Metal-Dependent Phosphohydrolase HD Region; HD-Hydrolase Domain-Containing Protein; Integral Membrane Protein Two-Component Signal Transducer; HAMP Domain-Containing Protein; Two Component Response Regulator Protein; Diguanylate Cyclase Domain Protein; HD Domain Protein; Response Regulator/Phosphatase; Two-Component Hybrid Sensor And Regulator Protein; Chemotaxis Protein; Response Regulator With HD-GYP Domain; Metal Dependent Phosphohydrolase HD Region; HD Domain/HAMP Domain-Containing Protein; Diguanylate Cyclase With GAF Sensor; Two-Component Response Regulator Fusion Protein; Response Regulator Containing A CheY-Like Receiver Domain; Multi-Sensor Signal Transduction Histidine Kinase

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MKPKFPKYIVTDLDSIVKRLGPIISRLEIEFLDFKEFFQSELFRNSSGFLNVIFYLTVSDLKKTQKEIHQQFQRNPLILS
RFILNENLDYVHSEDLKIEEELIFSVLPESSSDMVFNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTRVGISLADE
KDINKLLREIIFSAREIAIADSGSLYLVEKDELGLVRNLRFKISSMDIDTEEFLLPINKSSVAGYVAATGKILNIPDVYN
LPEDSEYKFNRNFDVLSNYHTKSMLVVPMKNHRNEVVGVIQLINKKRNFNQKLTLEQMRGNDVFPFDDYSAQLVMGVAGQ
AAVAIQNNHLLQEIEALFEGFVTASVNAIESRDPTTSGHSFRVAVLTVGLAETVDLIREGKYKNTKFSKEQIKEIRYASL
LHDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESRILQKKTDYLKKHGAVGFADYETSLEFELKVEYQKLDQM
FQIVVDSNEPSILEESNFQKLEEIAKVNYSTTGGEKLSLISPYEFGFLTIKKGSLDFAERKEIESHVEHTFQFLSKIPWT
GDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPIQSKIMAISDIFDALTDKDRPYKRAVPIERALDILQMEARENHVDQDL
LKIFIEGKVYDKLYYSGYLR

Sequences:

>Translated_660_residues
MKPKFPKYIVTDLDSIVKRLGPIISRLEIEFLDFKEFFQSELFRNSSGFLNVIFYLTVSDLKKTQKEIHQQFQRNPLILS
RFILNENLDYVHSEDLKIEEELIFSVLPESSSDMVFNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTRVGISLADE
KDINKLLREIIFSAREIAIADSGSLYLVEKDELGLVRNLRFKISSMDIDTEEFLLPINKSSVAGYVAATGKILNIPDVYN
LPEDSEYKFNRNFDVLSNYHTKSMLVVPMKNHRNEVVGVIQLINKKRNFNQKLTLEQMRGNDVFPFDDYSAQLVMGVAGQ
AAVAIQNNHLLQEIEALFEGFVTASVNAIESRDPTTSGHSFRVAVLTVGLAETVDLIREGKYKNTKFSKEQIKEIRYASL
LHDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESRILQKKTDYLKKHGAVGFADYETSLEFELKVEYQKLDQM
FQIVVDSNEPSILEESNFQKLEEIAKVNYSTTGGEKLSLISPYEFGFLTIKKGSLDFAERKEIESHVEHTFQFLSKIPWT
GDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPIQSKIMAISDIFDALTDKDRPYKRAVPIERALDILQMEARENHVDQDL
LKIFIEGKVYDKLYYSGYLR
>Mature_660_residues
MKPKFPKYIVTDLDSIVKRLGPIISRLEIEFLDFKEFFQSELFRNSSGFLNVIFYLTVSDLKKTQKEIHQQFQRNPLILS
RFILNENLDYVHSEDLKIEEELIFSVLPESSSDMVFNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTRVGISLADE
KDINKLLREIIFSAREIAIADSGSLYLVEKDELGLVRNLRFKISSMDIDTEEFLLPINKSSVAGYVAATGKILNIPDVYN
LPEDSEYKFNRNFDVLSNYHTKSMLVVPMKNHRNEVVGVIQLINKKRNFNQKLTLEQMRGNDVFPFDDYSAQLVMGVAGQ
AAVAIQNNHLLQEIEALFEGFVTASVNAIESRDPTTSGHSFRVAVLTVGLAETVDLIREGKYKNTKFSKEQIKEIRYASL
LHDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESRILQKKTDYLKKHGAVGFADYETSLEFELKVEYQKLDQM
FQIVVDSNEPSILEESNFQKLEEIAKVNYSTTGGEKLSLISPYEFGFLTIKKGSLDFAERKEIESHVEHTFQFLSKIPWT
GDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPIQSKIMAISDIFDALTDKDRPYKRAVPIERALDILQMEARENHVDQDL
LKIFIEGKVYDKLYYSGYLR

Specific function: Unknown

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI226246591, Length=143, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI219802706, Length=143, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI4505657, Length=143, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI61744435, Length=151, Percent_Identity=34.4370860927152, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI61744430, Length=151, Percent_Identity=34.4370860927152, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI61744432, Length=151, Percent_Identity=34.4370860927152, Blast_Score=76, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.4.17

Molecular weight: Translated: 76109; Mature: 76109

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKFPKYIVTDLDSIVKRLGPIISRLEIEFLDFKEFFQSELFRNSSGFLNVIFYLTVSD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCEEEEEEEEHHH
LKKTQKEIHQQFQRNPLILSRFILNENLDYVHSEDLKIEEELIFSVLPESSSDMVFNKTF
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEHHHH
LNAFTQLQMITDQFDLQHKVNTTKYEISKLTRVGISLADEKDINKLLREIIFSAREIAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEE
DSGSLYLVEKDELGLVRNLRFKISSMDIDTEEFLLPINKSSVAGYVAATGKILNIPDVYN
CCCCEEEEECCCCCHHHHHEEEEECCCCCHHHHEEECCCCCCCEEEEECCEEECCCCCCC
LPEDSEYKFNRNFDVLSNYHTKSMLVVPMKNHRNEVVGVIQLINKKRNFNQKLTLEQMRG
CCCCCCEEECCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEHHHHCC
NDVFPFDDYSAQLVMGVAGQAAVAIQNNHLLQEIEALFEGFVTASVNAIESRDPTTSGHS
CCCCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FRVAVLTVGLAETVDLIREGKYKNTKFSKEQIKEIRYASLLHDFGKVGVREKVLVKSKKL
EEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
EDYELELIRWRFEYIKKDIESRILQKKTDYLKKHGAVGFADYETSLEFELKVEYQKLDQM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHHHH
FQIVVDSNEPSILEESNFQKLEEIAKVNYSTTGGEKLSLISPYEFGFLTIKKGSLDFAER
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHH
KEIESHVEHTFQFLSKIPWTGDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPIQSKIMAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SDIFDALTDKDRPYKRAVPIERALDILQMEARENHVDQDLLKIFIEGKVYDKLYYSGYLR
HHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKPKFPKYIVTDLDSIVKRLGPIISRLEIEFLDFKEFFQSELFRNSSGFLNVIFYLTVSD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCEEEEEEEEHHH
LKKTQKEIHQQFQRNPLILSRFILNENLDYVHSEDLKIEEELIFSVLPESSSDMVFNKTF
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEHHHH
LNAFTQLQMITDQFDLQHKVNTTKYEISKLTRVGISLADEKDINKLLREIIFSAREIAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEE
DSGSLYLVEKDELGLVRNLRFKISSMDIDTEEFLLPINKSSVAGYVAATGKILNIPDVYN
CCCCEEEEECCCCCHHHHHEEEEECCCCCHHHHEEECCCCCCCEEEEECCEEECCCCCCC
LPEDSEYKFNRNFDVLSNYHTKSMLVVPMKNHRNEVVGVIQLINKKRNFNQKLTLEQMRG
CCCCCCEEECCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEHHHHCC
NDVFPFDDYSAQLVMGVAGQAAVAIQNNHLLQEIEALFEGFVTASVNAIESRDPTTSGHS
CCCCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FRVAVLTVGLAETVDLIREGKYKNTKFSKEQIKEIRYASLLHDFGKVGVREKVLVKSKKL
EEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
EDYELELIRWRFEYIKKDIESRILQKKTDYLKKHGAVGFADYETSLEFELKVEYQKLDQM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHHHH
FQIVVDSNEPSILEESNFQKLEEIAKVNYSTTGGEKLSLISPYEFGFLTIKKGSLDFAER
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHH
KEIESHVEHTFQFLSKIPWTGDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPIQSKIMAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SDIFDALTDKDRPYKRAVPIERALDILQMEARENHVDQDLLKIFIEGKVYDKLYYSGYLR
HHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside 3',5'-cyclic phosphate; H2O

Specific reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA