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The map label for this gene is ank3

Identifier: 45656934

GI number: 45656934

Start: 1291814

End: 1293163

Strand: Direct

Name: ank3

Synonym: LIC11050

Alternate gene names: NA

Gene position: 1291814-1293163 (Clockwise)

Preceding gene: 45656931

Following gene: 45656936

Centisome position: 30.2

GC content: 40.22

Gene sequence:

>1350_bases
ATGGATACAGCCGCATTATTCAAAGCGATTCGAGAGAAAAATTTAGCTGTAGTAAAAAAACTTTTAGACGAAGGTTGTGA
TCCTTCTTGTTACCAAAAAGATGTATATAACAATGCTCTGAGTCTTGCCGCTTATATGAGACAACCAGAAATGGTAGAGT
ATCTTATTCAAAAAGGAGCTCGTGTTAACGATAGAACTAAAGGAGAACGTATTGCCTTGCATAATGCGGTTTGGCAATAC
GATAAACGTTCTGTAGAACTTCTTTTGGAAGCTGGATCGGACATTCACGCAGCCGATCAATCTAACTGGACTCCAATTTG
GCTTGCGTCTAAATGGGAACCTTTTATCTCCCTCATAGAACAAGGCGCTTTTGTAGAAGGTAGAGATAAAGAAGGAAAAA
CTTTACTCAATAAAATAGCTTTAGCAACTGCATCTTTTAGTCAAGAAGACGGAATGAAAATGCTGACTAAACTTGTAGAG
TTAGGTTTAAGAGTTTCTGATGAAAAACCGGACTCCTATGGAGAAACTCTATTGATGAAAACGATAGAAGATACTCCATA
TAGAAACAAAAATCAGATTGCTTATTGGTTGATCGAACAGGGGATGGATCCTTTGCACGTAAGTCATGCCGGATGTACTG
CGCTCCATTATGCGTGTAAATCCGGAGATTTGGATATGGTTAGGACGTTAGTCTCTCTTGGAGCGGATATAAATGCAGTC
ATAACTCAAGACGGATCTGGTTTTGAAGCGGGTATGAGTCCGCTTGATTCTGTAACGAAATACGGCTCCAAGCGTAAAGC
CATTCTCGCGGAACTGAAAAAGAACGGAGCAAGTAAGAAGCCGACTATGGATTTAGAAATAGAGGATAATGTAATACGAC
TGAAAGGTAAGGATCGTAGAACGATTTTAGAAAATATGTTGGAGATAACAAAAAACCTGCAAGAAAACGTATTTTCGCAT
CCCGATTACGAAAGTCCGGATCACTGGCTTGAATGGGAATTGCCTGGAGAAGAAATAGACGAAGCGGACTTCTTTTTAAA
ATGTATAAACAAACCGGAATTACGCCTACTTGTTGCGCGTTATGTGTCACAGATACTGATCGCGAATGAAAAAGAAGGAG
ACACGATTTATGTGCATGAAGAGTTAGAGGCGGGAGGATATGCCATGCAGGCGCTCGTTTCGACCGGGGAAGTGGAATAT
TTGGAATTACTTAAGAAATGCATTCTTTCGATTGATATTGATCATACGGTTCATTTGCACGAACTTATGGATGTAGCACG
CTCTAAATATTCTCAGGAACAACTCGCTCCGATAGAAAACACATTGGATGAATTAGGGTTGGCTCGTTAG

Upstream 100 bases:

>100_bases
AAAAAGAAACAGAAGTAATTTCATAAATGGATTTATGAAATGTAGTAAAAACAACCGATCTAAAAAAGAATTTAGATTAA
AAAGAAAATAAAACAGAAAT

Downstream 100 bases:

>100_bases
CTCGTTTTTAATTTTGTAGGATCTGACTTGTAGTATGTGTACCGAACGGTTTTTCGTTTTATCGTTCGATCTACATATTA
CAAAAAAAAATTATTCCCCG

Product: ankyrin G domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MDTAALFKAIREKNLAVVKKLLDEGCDPSCYQKDVYNNALSLAAYMRQPEMVEYLIQKGARVNDRTKGERIALHNAVWQY
DKRSVELLLEAGSDIHAADQSNWTPIWLASKWEPFISLIEQGAFVEGRDKEGKTLLNKIALATASFSQEDGMKMLTKLVE
LGLRVSDEKPDSYGETLLMKTIEDTPYRNKNQIAYWLIEQGMDPLHVSHAGCTALHYACKSGDLDMVRTLVSLGADINAV
ITQDGSGFEAGMSPLDSVTKYGSKRKAILAELKKNGASKKPTMDLEIEDNVIRLKGKDRRTILENMLEITKNLQENVFSH
PDYESPDHWLEWELPGEEIDEADFFLKCINKPELRLLVARYVSQILIANEKEGDTIYVHEELEAGGYAMQALVSTGEVEY
LELLKKCILSIDIDHTVHLHELMDVARSKYSQEQLAPIENTLDELGLAR

Sequences:

>Translated_449_residues
MDTAALFKAIREKNLAVVKKLLDEGCDPSCYQKDVYNNALSLAAYMRQPEMVEYLIQKGARVNDRTKGERIALHNAVWQY
DKRSVELLLEAGSDIHAADQSNWTPIWLASKWEPFISLIEQGAFVEGRDKEGKTLLNKIALATASFSQEDGMKMLTKLVE
LGLRVSDEKPDSYGETLLMKTIEDTPYRNKNQIAYWLIEQGMDPLHVSHAGCTALHYACKSGDLDMVRTLVSLGADINAV
ITQDGSGFEAGMSPLDSVTKYGSKRKAILAELKKNGASKKPTMDLEIEDNVIRLKGKDRRTILENMLEITKNLQENVFSH
PDYESPDHWLEWELPGEEIDEADFFLKCINKPELRLLVARYVSQILIANEKEGDTIYVHEELEAGGYAMQALVSTGEVEY
LELLKKCILSIDIDHTVHLHELMDVARSKYSQEQLAPIENTLDELGLAR
>Mature_449_residues
MDTAALFKAIREKNLAVVKKLLDEGCDPSCYQKDVYNNALSLAAYMRQPEMVEYLIQKGARVNDRTKGERIALHNAVWQY
DKRSVELLLEAGSDIHAADQSNWTPIWLASKWEPFISLIEQGAFVEGRDKEGKTLLNKIALATASFSQEDGMKMLTKLVE
LGLRVSDEKPDSYGETLLMKTIEDTPYRNKNQIAYWLIEQGMDPLHVSHAGCTALHYACKSGDLDMVRTLVSLGADINAV
ITQDGSGFEAGMSPLDSVTKYGSKRKAILAELKKNGASKKPTMDLEIEDNVIRLKGKDRRTILENMLEITKNLQENVFSH
PDYESPDHWLEWELPGEEIDEADFFLKCINKPELRLLVARYVSQILIANEKEGDTIYVHEELEAGGYAMQALVSTGEVEY
LELLKKCILSIDIDHTVHLHELMDVARSKYSQEQLAPIENTLDELGLAR

Specific function: Unknown

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 18 ANK repeats [H]

Homologues:

Organism=Homo sapiens, GI32967601, Length=234, Percent_Identity=28.6324786324786, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI52426737, Length=321, Percent_Identity=26.791277258567, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI188595682, Length=321, Percent_Identity=26.791277258567, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI87239981, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI52426735, Length=321, Percent_Identity=26.791277258567, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI13376842, Length=261, Percent_Identity=28.735632183908, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI70780355, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI70780353, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI70780359, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI215598574, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI70780357, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI46519154, Length=261, Percent_Identity=25.6704980842912, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI46519151, Length=261, Percent_Identity=25.6704980842912, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI24233530, Length=262, Percent_Identity=28.2442748091603, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI68131557, Length=215, Percent_Identity=27.4418604651163, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71981414, Length=277, Percent_Identity=27.4368231046931, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71981389, Length=279, Percent_Identity=27.2401433691756, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145251, Length=279, Percent_Identity=27.2401433691756, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17542700, Length=279, Percent_Identity=27.2401433691756, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161082092, Length=309, Percent_Identity=25.5663430420712, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161082089, Length=309, Percent_Identity=25.5663430420712, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161082085, Length=263, Percent_Identity=28.1368821292776, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161082099, Length=263, Percent_Identity=28.1368821292776, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161082110, Length=309, Percent_Identity=25.5663430420712, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161082081, Length=309, Percent_Identity=25.5663430420712, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161082106, Length=309, Percent_Identity=25.5663430420712, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161082096, Length=309, Percent_Identity=25.5663430420712, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356741, Length=258, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002110
- InterPro:   IPR020683
- InterPro:   IPR007685 [H]

Pfam domain/function: PF00023 Ank; PF04607 RelA_SpoT [H]

EC number: NA

Molecular weight: Translated: 50625; Mature: 50625

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAALFKAIREKNLAVVKKLLDEGCDPSCYQKDVYNNALSLAAYMRQPEMVEYLIQKGA
CCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
RVNDRTKGERIALHNAVWQYDKRSVELLLEAGSDIHAADQSNWTPIWLASKWEPFISLIE
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
QGAFVEGRDKEGKTLLNKIALATASFSQEDGMKMLTKLVELGLRVSDEKPDSYGETLLMK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TIEDTPYRNKNQIAYWLIEQGMDPLHVSHAGCTALHYACKSGDLDMVRTLVSLGADINAV
HHHCCCCCCCCCEEEEEECCCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
ITQDGSGFEAGMSPLDSVTKYGSKRKAILAELKKNGASKKPTMDLEIEDNVIRLKGKDRR
EECCCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCHH
TILENMLEITKNLQENVFSHPDYESPDHWLEWELPGEEIDEADFFLKCINKPELRLLVAR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHH
YVSQILIANEKEGDTIYVHEELEAGGYAMQALVSTGEVEYLELLKKCILSIDIDHTVHLH
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHH
ELMDVARSKYSQEQLAPIENTLDELGLAR
HHHHHHHHHHCHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure
MDTAALFKAIREKNLAVVKKLLDEGCDPSCYQKDVYNNALSLAAYMRQPEMVEYLIQKGA
CCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
RVNDRTKGERIALHNAVWQYDKRSVELLLEAGSDIHAADQSNWTPIWLASKWEPFISLIE
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
QGAFVEGRDKEGKTLLNKIALATASFSQEDGMKMLTKLVELGLRVSDEKPDSYGETLLMK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TIEDTPYRNKNQIAYWLIEQGMDPLHVSHAGCTALHYACKSGDLDMVRTLVSLGADINAV
HHHCCCCCCCCCEEEEEECCCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
ITQDGSGFEAGMSPLDSVTKYGSKRKAILAELKKNGASKKPTMDLEIEDNVIRLKGKDRR
EECCCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCHH
TILENMLEITKNLQENVFSHPDYESPDHWLEWELPGEEIDEADFFLKCINKPELRLLVAR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHH
YVSQILIANEKEGDTIYVHEELEAGGYAMQALVSTGEVEYLELLKKCILSIDIDHTVHLH
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHH
ELMDVARSKYSQEQLAPIENTLDELGLAR
HHHHHHHHHHCHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA