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The map label for this gene is acps

Identifier: 45656737

GI number: 45656737

Start: 1025222

End: 1025602

Strand: Direct

Name: acps

Synonym: LIC10846

Alternate gene names: 45656737

Gene position: 1025222-1025602 (Clockwise)

Preceding gene: 45656736

Following gene: 45656738

Centisome position: 23.97

GC content: 39.37

Gene sequence:

>381_bases
ATGAAAATTTCCGTCGGTAATGATATCGTTGAAAATTCTCGGATTCGTGATCTTTTAGAAAAACACGGAGATCGTTTTTT
GAAACGGGTCTTTTCGGAATCCGAAAGAGAATATTGTTCCAATCGTAAAGATCCGATTCCACACTTAAGTGGAAGGTTCT
GCGTCAAAGAAGCTTTTATCAAAGCGATTGAGCCAGGAGATCATGTGATTTTAGATATGAGGGAAATCGAACTTTTCGGA
AAGGAATTTGGAAAAAAAGAATTGGTACTGCATGGAAAATCCAAAGAATTGTTTCTTACCAAAGGATACAGCGGTTGTTC
GGTTTCGATCAGTCACGCTGAAAATTATTCCACCGCCGTCGTGGTGCTTTACAAGGAGTGA

Upstream 100 bases:

>100_bases
AACAGGATCAAAATCAAAGTAACGGCGGGAAAGAACCAGACGGAGAGGGAGAGGAAAATACGATCGAACCAGATACTAAT
CCGGAACTTTTAGAAGAAGA

Downstream 100 bases:

>100_bases
TCTATGATTTCGGAAGCGATGAAACAAACTATTCAGTTCTACAACGAAGGTCTTAACTTGTATAAAACCAGAAAGTTTAC
CGAAGCGCTTGAAAAATTTA

Product: acyl carrier protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFIKAIEPGDHVILDMREIELFG
KEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAVVVLYKE

Sequences:

>Translated_126_residues
MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFIKAIEPGDHVILDMREIELFG
KEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAVVVLYKE
>Mature_126_residues
MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFIKAIEPGDHVILDMREIELFG
KEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAVVVLYKE

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=121, Percent_Identity=33.0578512396694, Blast_Score=73, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_LEPIC (Q72U18)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_000823.1
- ProteinModelPortal:   Q72U18
- SMR:   Q72U18
- GeneID:   2770485
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC10846
- HOGENOM:   HBG734479
- OMA:   HIGTDII
- ProtClustDB:   CLSK574788
- BioCyc:   LINT267671:LIC_10846-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14420; Mature: 14420

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFI
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KAIEPGDHVILDMREIELFGKEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAV
HHCCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCCEEE
VVLYKE
EEEEEC
>Mature Secondary Structure
MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFI
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KAIEPGDHVILDMREIELFGKEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAV
HHCCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCCEEE
VVLYKE
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA