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The map label for this gene is hflX

Identifier: 45656474

GI number: 45656474

Start: 701450

End: 703006

Strand: Reverse

Name: hflX

Synonym: LIC10576

Alternate gene names: 45656474

Gene position: 703006-701450 (Counterclockwise)

Preceding gene: 45656477

Following gene: 45656473

Centisome position: 16.44

GC content: 37.64

Gene sequence:

>1557_bases
GTGTTGGTGGGTTCTGATAATTCGATCGAAATTCCATTTTTAGATAGACTTCGTATTTCCGAGGCAAGATTAAGAGGTCT
CAGATTAGTTCATACTCATTTAAAGGGTGAACCCTTAAATCAAGAGGATTTAACCGACTTAGCTTTGTTGCGTCTGGATT
ATTTTACCGCTATCGTTATGGATCATTTCGGAAATCCAAACGGATATTATTCCGCTCATCTCAATCCGGAATCCGAAGAC
GAACTTTGGACCGTTCTTCCTAAACAATATCCCGGACAACTTACGGAAGGAATTCTAGAAGAAATCTTAGAGATAGAATC
TAGACTTTCTCGTTCCAAAAAGAATCTCAAAGACGCTCAAAAGGAAAACCGTGCTTTTTTAGTCGGTGTTTATCCGGAAA
GAAACGTGGGTAGGCATCCTTCTTTGTCTATGGAGGAATTAAAAGAACTTTGTAAAACCGCGGAAGTCCACGTTGTAGAT
ACGTTTATACAAAGGAAAAACCGTCTTGATCCTTCTACGGTTTTAGGAAAAGGAAAACTAGAAGAAATCATTTTGAAGGC
GATTCAAAAACACGTGGAACTTCTAGTATTCGATCTTGAACTGACTCCTTCTCAAGCAAAAAAGATTTCGGATATTGCAG
ACATCAAGGTAATCGATAGAACACAACTCATCTTAGATATTTTTGCAAGAAATGCAAAAAGTAGAGACGGTAAACTTCAG
GTTGAGCTTGCACAATTAAAATATCTCAAAGGGCGTCTAACGGAGTTGGACGATAACATGTCGAGATTGACTGGTGGAAT
TGGAGGAAGAGGTCCCGGAGAAACAAAATTAGAAATCGGTAAACGAAGAGTTGAAGAGAGAATTACTAGACTAGAAGTGG
AACTTAAGTCTTTAAAAAAGCGTAGAGAAATTAATCGTAGACAGAGAAAGAAAAACGAATTACCTGCCGTCGGAATCGTT
GGTTATACAAACGCAGGAAAATCCACTTTCCTAAATGCTCTGACAAACAGCGAAGTACTTTCGGAAAATAAGTTGTTCGC
AACTCTGGATCCTACTACAAGAAGGATTCGTTTTCCAGAGGAAAGGGAAATTATCATTTCAGATACGGTCGGGTTTATAC
ACGACCTTCCTCCCGAACTTTCTAACGCATTTAAGGCAACCTTAGAAGAACTGGGAGATTCAGACCTTTTAGTTCATGTT
GTAGACGTTTCCAATCCGGATTACAAACTTCAAATGGAGGCGGTTGAAAAAATTTTAGAAGAATTAGAACTTTCTCATAT
ACCTATGATCCAAGTGTTCAATAAAATTGATCGTCTTGAAAAATTTAAAATCTGGGTAATTGAAAACGGTTATAAAAAAT
CTTCTTCGGTAGATCACGGTCCGGGTTTGGAAGCAATTACAGATTTAAAAGAGGAATTAGGAATTGATACTTTTTCCGAT
TCGATTTTAGTTTCTGCATTTCAAGGTTGGGGTTTAAAAACTTTTCTGGATCTTTTGGAAGATAGAATCTACAATTTGTC
TCGTTCTAATTATTCTAACACCAGTTCGGTTTACTGA

Upstream 100 bases:

>100_bases
AATCATCAATCAAGAACTGGCACGCAATATCTGCGAATTATCCTTAGAAATTGGCAAACAAATCGGAATTCTAATCGATC
GGTCTGGTTACGTCACCCAT

Downstream 100 bases:

>100_bases
TCTCTATAAAGTTGAGTGTCATAAATTTTTACTGTAAAATCCTGTTTTAACATAAAATATCGAATACTTTTTTAACTTGA
GTTAAGTATGAGAAAGAATT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLVGSDNSIEIPFLDRLRISEARLRGLRLVHTHLKGEPLNQEDLTDLALLRLDYFTAIVMDHFGNPNGYYSAHLNPESED
ELWTVLPKQYPGQLTEGILEEILEIESRLSRSKKNLKDAQKENRAFLVGVYPERNVGRHPSLSMEELKELCKTAEVHVVD
TFIQRKNRLDPSTVLGKGKLEEIILKAIQKHVELLVFDLELTPSQAKKISDIADIKVIDRTQLILDIFARNAKSRDGKLQ
VELAQLKYLKGRLTELDDNMSRLTGGIGGRGPGETKLEIGKRRVEERITRLEVELKSLKKRREINRRQRKKNELPAVGIV
GYTNAGKSTFLNALTNSEVLSENKLFATLDPTTRRIRFPEEREIIISDTVGFIHDLPPELSNAFKATLEELGDSDLLVHV
VDVSNPDYKLQMEAVEKILEELELSHIPMIQVFNKIDRLEKFKIWVIENGYKKSSSVDHGPGLEAITDLKEELGIDTFSD
SILVSAFQGWGLKTFLDLLEDRIYNLSRSNYSNTSSVY

Sequences:

>Translated_518_residues
MLVGSDNSIEIPFLDRLRISEARLRGLRLVHTHLKGEPLNQEDLTDLALLRLDYFTAIVMDHFGNPNGYYSAHLNPESED
ELWTVLPKQYPGQLTEGILEEILEIESRLSRSKKNLKDAQKENRAFLVGVYPERNVGRHPSLSMEELKELCKTAEVHVVD
TFIQRKNRLDPSTVLGKGKLEEIILKAIQKHVELLVFDLELTPSQAKKISDIADIKVIDRTQLILDIFARNAKSRDGKLQ
VELAQLKYLKGRLTELDDNMSRLTGGIGGRGPGETKLEIGKRRVEERITRLEVELKSLKKRREINRRQRKKNELPAVGIV
GYTNAGKSTFLNALTNSEVLSENKLFATLDPTTRRIRFPEEREIIISDTVGFIHDLPPELSNAFKATLEELGDSDLLVHV
VDVSNPDYKLQMEAVEKILEELELSHIPMIQVFNKIDRLEKFKIWVIENGYKKSSSVDHGPGLEAITDLKEELGIDTFSD
SILVSAFQGWGLKTFLDLLEDRIYNLSRSNYSNTSSVY
>Mature_518_residues
MLVGSDNSIEIPFLDRLRISEARLRGLRLVHTHLKGEPLNQEDLTDLALLRLDYFTAIVMDHFGNPNGYYSAHLNPESED
ELWTVLPKQYPGQLTEGILEEILEIESRLSRSKKNLKDAQKENRAFLVGVYPERNVGRHPSLSMEELKELCKTAEVHVVD
TFIQRKNRLDPSTVLGKGKLEEIILKAIQKHVELLVFDLELTPSQAKKISDIADIKVIDRTQLILDIFARNAKSRDGKLQ
VELAQLKYLKGRLTELDDNMSRLTGGIGGRGPGETKLEIGKRRVEERITRLEVELKSLKKRREINRRQRKKNELPAVGIV
GYTNAGKSTFLNALTNSEVLSENKLFATLDPTTRRIRFPEEREIIISDTVGFIHDLPPELSNAFKATLEELGDSDLLVHV
VDVSNPDYKLQMEAVEKILEELELSHIPMIQVFNKIDRLEKFKIWVIENGYKKSSSVDHGPGLEAITDLKEELGIDTFSD
SILVSAFQGWGLKTFLDLLEDRIYNLSRSNYSNTSSVY

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=189, Percent_Identity=37.037037037037, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI310133118, Length=198, Percent_Identity=35.8585858585859, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310124269, Length=171, Percent_Identity=38.5964912280702, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI310124267, Length=171, Percent_Identity=38.5964912280702, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI310124171, Length=171, Percent_Identity=38.5964912280702, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI310124169, Length=171, Percent_Identity=38.5964912280702, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1790615, Length=300, Percent_Identity=42.6666666666667, Blast_Score=245, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17561038, Length=317, Percent_Identity=28.7066246056782, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24650079, Length=285, Percent_Identity=34.0350877192982, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 58963; Mature: 58963

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVGSDNSIEIPFLDRLRISEARLRGLRLVHTHLKGEPLNQEDLTDLALLRLDYFTAIVM
CEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
DHFGNPNGYYSAHLNPESEDELWTVLPKQYPGQLTEGILEEILEIESRLSRSKKNLKDAQ
HHCCCCCCEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KENRAFLVGVYPERNVGRHPSLSMEELKELCKTAEVHVVDTFIQRKNRLDPSTVLGKGKL
HCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH
EEIILKAIQKHVELLVFDLELTPSQAKKISDIADIKVIDRTQLILDIFARNAKSRDGKLQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCEEE
VELAQLKYLKGRLTELDDNMSRLTGGIGGRGPGETKLEIGKRRVEERITRLEVELKSLKK
EEHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RREINRRQRKKNELPAVGIVGYTNAGKSTFLNALTNSEVLSENKLFATLDPTTRRIRFPE
HHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHCCCCCC
EREIIISDTVGFIHDLPPELSNAFKATLEELGDSDLLVHVVDVSNPDYKLQMEAVEKILE
CCCEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHH
ELELSHIPMIQVFNKIDRLEKFKIWVIENGYKKSSSVDHGPGLEAITDLKEELGIDTFSD
HHHHCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
SILVSAFQGWGLKTFLDLLEDRIYNLSRSNYSNTSSVY
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLVGSDNSIEIPFLDRLRISEARLRGLRLVHTHLKGEPLNQEDLTDLALLRLDYFTAIVM
CEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
DHFGNPNGYYSAHLNPESEDELWTVLPKQYPGQLTEGILEEILEIESRLSRSKKNLKDAQ
HHCCCCCCEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KENRAFLVGVYPERNVGRHPSLSMEELKELCKTAEVHVVDTFIQRKNRLDPSTVLGKGKL
HCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH
EEIILKAIQKHVELLVFDLELTPSQAKKISDIADIKVIDRTQLILDIFARNAKSRDGKLQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCEEE
VELAQLKYLKGRLTELDDNMSRLTGGIGGRGPGETKLEIGKRRVEERITRLEVELKSLKK
EEHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RREINRRQRKKNELPAVGIVGYTNAGKSTFLNALTNSEVLSENKLFATLDPTTRRIRFPE
HHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHCCCCCC
EREIIISDTVGFIHDLPPELSNAFKATLEELGDSDLLVHVVDVSNPDYKLQMEAVEKILE
CCCEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHH
ELELSHIPMIQVFNKIDRLEKFKIWVIENGYKKSSSVDHGPGLEAITDLKEELGIDTFSD
HHHHCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
SILVSAFQGWGLKTFLDLLEDRIYNLSRSNYSNTSSVY
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]