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The map label for this gene is 304570490

Identifier: 304570490

GI number: 304570490

Start: 1399134

End: 1400042

Strand: Direct

Name: 304570490

Synonym: NA

Alternate gene names: NA

Gene position: 1399134-1400042 (Clockwise)

Preceding gene: 45657008

Following gene: 45657019

Centisome position: 32.71

GC content: 36.08

Gene sequence:

>909_bases
TTGGAGAAGCACTTAGAACGTATCGGTTTAGTTTATCACCCGGATTATAACCTAGATCTGGGGCCTCACGTATTTCCGGC
AAGGAAATACCAAATGGTTTATGATCTTGTAAAACGAGATTCTAAACTTTCTAATCTTTATATCTATAAACCGGACCTAG
CTAAAACTAAAGACTTATCTTTGGTTCATACTCAAGAATTCTTAGATGATTTTTTCTCTCTCAACATCACTGAAAGAACT
CAGTATTCCGAACTTCCTCTTACAAAACAAATCGTTCATAGTTTTGTTTTAGCCGTAGGAGGTACTATTCTCTCTATGGA
ACTGACTCAAAAATACAAGTTTGTTTATCACATAGGTGGGGGGTTTCATCATAGTATGCCGGATCGGGCGGAAGGATTTT
GCTATTTGAATGATGCGGCGATTGCGAGTAAGTTGTATCAGAAAGAATATCCAGATAAAAAAATTCTTTTTATCGATTTG
GATCTTCACCAAGGCAATGGTAATTCATTCATATTTCAAAATGACCCAGACGTATTTACATTTTCCATGCATCAGGAGAA
TTTATATCCAAAAAAAGAAAAATCCGATTTAGATATTTCTTTAGAAGAAGGAATCGGTGATAAAGAATATCTTGAGCTTT
TGGAAAAATCCTTACGTAAAATTGAATCTGATTTTAAACCGGATTTGATTTTTTATATCGCGGGAGCCGATCCGTTTGAA
GGAGATTCTCTTGGTGATTTGAAACTTACGTTTCAGGGTTTGAGAAAAAGGGATCAGATCGTAAGAGACTTTGCGTATTC
GTTGAACGACACTCGGGTTGTTATTCTTCCTGCTGGAGGATATGCAAAAGATTTTTACGATACGGTAACGATCCATTATA
ATACGATTAAAATATTTGCGGCCGACTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: histone deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:
NA

Sequences:

>Translated_302_residues
MEKHLERIGLVYHPDYNLDLGPHVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLSLVHTQEFLDDFFSLNITERT
QYSELPLTKQIVHSFVLAVGGTILSMELTQKYKFVYHIGGGFHHSMPDRAEGFCYLNDAAIASKLYQKEYPDKKILFIDL
DLHQGNGNSFIFQNDPDVFTFSMHQENLYPKKEKSDLDISLEEGIGDKEYLELLEKSLRKIESDFKPDLIFYIAGADPFE
GDSLGDLKLTFQGLRKRDQIVRDFAYSLNDTRVVILPAGGYAKDFYDTVTIHYNTIKIFAAD
>Mature_302_residues
MEKHLERIGLVYHPDYNLDLGPHVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLSLVHTQEFLDDFFSLNITERT
QYSELPLTKQIVHSFVLAVGGTILSMELTQKYKFVYHIGGGFHHSMPDRAEGFCYLNDAAIASKLYQKEYPDKKILFIDL
DLHQGNGNSFIFQNDPDVFTFSMHQENLYPKKEKSDLDISLEEGIGDKEYLELLEKSLRKIESDFKPDLIFYIAGADPFE
GDSLGDLKLTFQGLRKRDQIVRDFAYSLNDTRVVILPAGGYAKDFYDTVTIHYNTIKIFAAD

Specific function: Putative deacetylase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=293, Percent_Identity=31.3993174061433, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI209862883, Length=266, Percent_Identity=30.4511278195489, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI8923769, Length=297, Percent_Identity=25.2525252525253, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI13128860, Length=284, Percent_Identity=24.2957746478873, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI293336691, Length=266, Percent_Identity=24.0601503759398, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI30795202, Length=209, Percent_Identity=30.622009569378, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI30795204, Length=209, Percent_Identity=30.622009569378, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI17158039, Length=209, Percent_Identity=30.622009569378, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI13128864, Length=297, Percent_Identity=23.2323232323232, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI153085395, Length=137, Percent_Identity=32.8467153284672, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI62750349, Length=179, Percent_Identity=31.2849162011173, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI62750347, Length=179, Percent_Identity=31.2849162011173, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI262073092, Length=232, Percent_Identity=25.4310344827586, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI262073088, Length=174, Percent_Identity=28.1609195402299, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13128862, Length=302, Percent_Identity=23.5099337748344, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI148539870, Length=157, Percent_Identity=31.8471337579618, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169234807, Length=157, Percent_Identity=31.8471337579618, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20070354, Length=274, Percent_Identity=24.0875912408759, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193207430, Length=299, Percent_Identity=29.0969899665552, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17561978, Length=284, Percent_Identity=25.3521126760563, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540332, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193206283, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540334, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534739, Length=254, Percent_Identity=25.9842519685039, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508561, Length=284, Percent_Identity=22.887323943662, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193209491, Length=178, Percent_Identity=30.3370786516854, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537347, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=234, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=234, Percent_Identity=23.9316239316239, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=297, Percent_Identity=22.5589225589226, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324307, Length=181, Percent_Identity=29.2817679558011, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=176, Percent_Identity=30.6818181818182, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=173, Percent_Identity=30.635838150289, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649807, Length=304, Percent_Identity=29.2763157894737, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI281360899, Length=275, Percent_Identity=24.7272727272727, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24642146, Length=275, Percent_Identity=24.7272727272727, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24642144, Length=275, Percent_Identity=24.7272727272727, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24642142, Length=275, Percent_Identity=24.7272727272727, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24657891, Length=284, Percent_Identity=23.5915492957746, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644244, Length=303, Percent_Identity=24.4224422442244, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641720, Length=138, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281360801, Length=138, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281360799, Length=138, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34886; Mature: 34886

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHLERIGLVYHPDYNLDLGPHVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLS
CCCHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCE
LVHTQEFLDDFFSLNITERTQYSELPLTKQIVHSFVLAVGGTILSMELTQKYKFVYHIGG
EEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHCEEEEEEEECC
GFHHSMPDRAEGFCYLNDAAIASKLYQKEYPDKKILFIDLDLHQGNGNSFIFQNDPDVFT
CCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEECCCCEEE
FSMHQENLYPKKEKSDLDISLEEGIGDKEYLELLEKSLRKIESDFKPDLIFYIAGADPFE
EEECCCCCCCCCCCCCCCEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
GDSLGDLKLTFQGLRKRDQIVRDFAYSLNDTRVVILPAGGYAKDFYDTVTIHYNTIKIFA
CCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEEE
AD
CC
>Mature Secondary Structure
MEKHLERIGLVYHPDYNLDLGPHVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLS
CCCHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCE
LVHTQEFLDDFFSLNITERTQYSELPLTKQIVHSFVLAVGGTILSMELTQKYKFVYHIGG
EEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHCEEEEEEEECC
GFHHSMPDRAEGFCYLNDAAIASKLYQKEYPDKKILFIDLDLHQGNGNSFIFQNDPDVFT
CCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEECCCCEEE
FSMHQENLYPKKEKSDLDISLEEGIGDKEYLELLEKSLRKIESDFKPDLIFYIAGADPFE
EEECCCCCCCCCCCCCCCEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
GDSLGDLKLTFQGLRKRDQIVRDFAYSLNDTRVVILPAGGYAKDFYDTVTIHYNTIKIFA
CCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEEE
AD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]