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The map label for this gene is tldD [C]

Identifier: 45359051

GI number: 45359051

Start: 1447747

End: 1449123

Strand: Direct

Name: tldD [C]

Synonym: MMP1488

Alternate gene names: 45359051

Gene position: 1447747-1449123 (Clockwise)

Preceding gene: 45359050

Following gene: 45359053

Centisome position: 87.15

GC content: 35.29

Gene sequence:

>1377_bases
GTGAGTTTTTTAAACGATCTTGATTTAAACATTGAAAAACTTGAAAAATTGCTTGAAATTGGAACCTATGCAGATTTAAG
AATAGTTACTGGTGAATCAAACAACATCATACAAAAAGACGGAATAATAGACGAAATTTCTTCAGGTATTTCTTCAGGAG
TGATTGTAAGAGTGCTTGAAAAAAACGGATGGGGACTTGCTACTTCAAATAGCGTTTCCCTAAAAAACATTGAAGAAATA
ATTAAAAAAGCGCAGGGTATGGCAAAAATATCCAATATACATACAAAAAAATCGATTGAATTGAAAGAAATCCCCATAAT
TCAGGACAATACAAAAGCAGATGTAAAAATTCATCCTGAAAACATTTCAATCGAAGAAAAAAAAGAATATTTGAAATCAG
CACATGAAAACATGTCTGGAGAAAAAATAGTCAGCACTTCTGTTAGCTACAGCGATGGGGAAGGCCATTCTATTTTGATG
ACTAGTGAAGGAACTAGAATTGAAAATGAGAGTGTTAAAGCCCTTTTAAGAATGACTGCAATTGCAAAAGATGGAACATT
GCAGTTTGCATTTGATAGAATTGGCGGAAACGGATTTGAAGTAATTAAAAATGCAAAAATTGAAGAAATGGCTAAAAATA
CCAAAGAAAGAGCGGTAAGACTTTTAACTGCTGAAAGCTGTCCAAAAGGAACTTTTGACGTAATATTAGATCCAGAACTT
GCAGGCGTATTTATCCACGAAGCTGTAGGACACGCTGCTGAAGCAGACCTCGTTTTGCAGAATGACAGTGTATTTCACGA
TAAACTAGGAAATTCAGTTGGTAGCGAAGAAGTAACCGTAATTGATGACGCAACAATCGAAAAATCGTTTGGACAGTACA
AATACGACCATGAAGGAGTTAAGGGAGAAAAAACTACATTAATTGAAGATGGAGTTTTGAATGGATACTTACATTCAAGA
GAAACTGCTGGAAGACTTAACATGGACGTTACAGGAAATGCAAGGGCAGAAGGACTAAACAAACCAATTGTTAGAATGAG
CAATACGTACATTAAACCAGGTTCATGGAAATTTGACGAACTTTTAGAAGATACTAAAACAGGAATATTTTTAAAAGGTT
CAAGGGGCGGACAGGTAGATACAGGAAAAGGGCTTTTCCAGTTTAATGCTGTTGAAGCATTTTTAATTGAAGATGGAAAA
TTAACAAAACCATTAAGAGATGCAGGACTCAGCGGTGAAATTTTAGATATTTTACACCATATCGATGCAGTGTCTGACGA
ATTTGAATTAAGTGTTGGATACTGTGGAAAAGGAGGCCAGAGTGTTCCAGTAGGAGATGGTGGAGGAAGTGTTAGAACAA
AAACTACACTTTCTTAA

Upstream 100 bases:

>100_bases
TATACAGTTGAAGAAATGTCTGAAACAAAAACAGTCGTAATTCATAACATTTAATTAAAAGAAAATGAATTATCTTATTA
ATTATTAACTTGGTGAAATC

Downstream 100 bases:

>100_bases
CTTCGTGAAAATATGGATGAATTAGCAAATAATTTAATAAACGCATTATTTAGGGATTTAATCGATATTACATTGGATTT
ATTTTACCTGATAATTGCAT

Product: modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSFLNDLDLNIEKLEKLLEIGTYADLRIVTGESNNIIQKDGIIDEISSGISSGVIVRVLEKNGWGLATSNSVSLKNIEEI
IKKAQGMAKISNIHTKKSIELKEIPIIQDNTKADVKIHPENISIEEKKEYLKSAHENMSGEKIVSTSVSYSDGEGHSILM
TSEGTRIENESVKALLRMTAIAKDGTLQFAFDRIGGNGFEVIKNAKIEEMAKNTKERAVRLLTAESCPKGTFDVILDPEL
AGVFIHEAVGHAAEADLVLQNDSVFHDKLGNSVGSEEVTVIDDATIEKSFGQYKYDHEGVKGEKTTLIEDGVLNGYLHSR
ETAGRLNMDVTGNARAEGLNKPIVRMSNTYIKPGSWKFDELLEDTKTGIFLKGSRGGQVDTGKGLFQFNAVEAFLIEDGK
LTKPLRDAGLSGEILDILHHIDAVSDEFELSVGYCGKGGQSVPVGDGGGSVRTKTTLS

Sequences:

>Translated_458_residues
MSFLNDLDLNIEKLEKLLEIGTYADLRIVTGESNNIIQKDGIIDEISSGISSGVIVRVLEKNGWGLATSNSVSLKNIEEI
IKKAQGMAKISNIHTKKSIELKEIPIIQDNTKADVKIHPENISIEEKKEYLKSAHENMSGEKIVSTSVSYSDGEGHSILM
TSEGTRIENESVKALLRMTAIAKDGTLQFAFDRIGGNGFEVIKNAKIEEMAKNTKERAVRLLTAESCPKGTFDVILDPEL
AGVFIHEAVGHAAEADLVLQNDSVFHDKLGNSVGSEEVTVIDDATIEKSFGQYKYDHEGVKGEKTTLIEDGVLNGYLHSR
ETAGRLNMDVTGNARAEGLNKPIVRMSNTYIKPGSWKFDELLEDTKTGIFLKGSRGGQVDTGKGLFQFNAVEAFLIEDGK
LTKPLRDAGLSGEILDILHHIDAVSDEFELSVGYCGKGGQSVPVGDGGGSVRTKTTLS
>Mature_457_residues
SFLNDLDLNIEKLEKLLEIGTYADLRIVTGESNNIIQKDGIIDEISSGISSGVIVRVLEKNGWGLATSNSVSLKNIEEII
KKAQGMAKISNIHTKKSIELKEIPIIQDNTKADVKIHPENISIEEKKEYLKSAHENMSGEKIVSTSVSYSDGEGHSILMT
SEGTRIENESVKALLRMTAIAKDGTLQFAFDRIGGNGFEVIKNAKIEEMAKNTKERAVRLLTAESCPKGTFDVILDPELA
GVFIHEAVGHAAEADLVLQNDSVFHDKLGNSVGSEEVTVIDDATIEKSFGQYKYDHEGVKGEKTTLIEDGVLNGYLHSRE
TAGRLNMDVTGNARAEGLNKPIVRMSNTYIKPGSWKFDELLEDTKTGIFLKGSRGGQVDTGKGLFQFNAVEAFLIEDGKL
TKPLRDAGLSGEILDILHHIDAVSDEFELSVGYCGKGGQSVPVGDGGGSVRTKTTLS

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=30.4444444444444, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1790682, Length=437, Percent_Identity=20.8237986270023, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49756; Mature: 49625

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLNDLDLNIEKLEKLLEIGTYADLRIVTGESNNIIQKDGIIDEISSGISSGVIVRVLE
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHCCCCCCEEEEEEE
KNGWGLATSNSVSLKNIEEIIKKAQGMAKISNIHTKKSIELKEIPIIQDNTKADVKIHPE
CCCCCEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCEEEECCEEECCCCCEEEECCC
NISIEEKKEYLKSAHENMSGEKIVSTSVSYSDGEGHSILMTSEGTRIENESVKALLRMTA
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
IAKDGTLQFAFDRIGGNGFEVIKNAKIEEMAKNTKERAVRLLTAESCPKGTFDVILDPEL
HCCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCEEEEECCCH
AGVFIHEAVGHAAEADLVLQNDSVFHDKLGNSVGSEEVTVIDDATIEKSFGQYKYDHEGV
HHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCC
KGEKTTLIEDGVLNGYLHSRETAGRLNMDVTGNARAEGLNKPIVRMSNTYIKPGSWKFDE
CCCCEEEEECCCHHCHHHCCCCCCEEEEEECCCCHHCCCCCCEEEECCCEECCCCCCHHH
LLEDTKTGIFLKGSRGGQVDTGKGLFQFNAVEAFLIEDGKLTKPLRDAGLSGEILDILHH
HHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHCCCCCHHHHHHHH
IDAVSDEFELSVGYCGKGGQSVPVGDGGGSVRTKTTLS
HHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SFLNDLDLNIEKLEKLLEIGTYADLRIVTGESNNIIQKDGIIDEISSGISSGVIVRVLE
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHCCCCCCEEEEEEE
KNGWGLATSNSVSLKNIEEIIKKAQGMAKISNIHTKKSIELKEIPIIQDNTKADVKIHPE
CCCCCEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCEEEECCEEECCCCCEEEECCC
NISIEEKKEYLKSAHENMSGEKIVSTSVSYSDGEGHSILMTSEGTRIENESVKALLRMTA
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
IAKDGTLQFAFDRIGGNGFEVIKNAKIEEMAKNTKERAVRLLTAESCPKGTFDVILDPEL
HCCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCEEEEECCCH
AGVFIHEAVGHAAEADLVLQNDSVFHDKLGNSVGSEEVTVIDDATIEKSFGQYKYDHEGV
HHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCC
KGEKTTLIEDGVLNGYLHSRETAGRLNMDVTGNARAEGLNKPIVRMSNTYIKPGSWKFDE
CCCCEEEEECCCHHCHHHCCCCCCEEEEEECCCCHHCCCCCCEEEECCCEECCCCCCHHH
LLEDTKTGIFLKGSRGGQVDTGKGLFQFNAVEAFLIEDGKLTKPLRDAGLSGEILDILHH
HHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHCCCCCHHHHHHHH
IDAVSDEFELSVGYCGKGGQSVPVGDGGGSVRTKTTLS
HHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]