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The map label for this gene is moaB [H]

Identifier: 45359048

GI number: 45359048

Start: 1444866

End: 1445351

Strand: Direct

Name: moaB [H]

Synonym: MMP1485

Alternate gene names: 45359048

Gene position: 1444866-1445351 (Clockwise)

Preceding gene: 45359047

Following gene: 45359050

Centisome position: 86.98

GC content: 32.72

Gene sequence:

>486_bases
ATGCATGAGAGAATTTCCGATGTAAGATACGCAGTAATTACTGTAAGTGACAGCCGATTTAATGAAATAATTTCAGGGCA
CGATATAACCGATAAATCAGGGGAATTTCTAAAAGATGAATTGGGTGCAAAAATCTACCATTTAATTCCGGACAGTAAAA
CGATGTTAGAAGGATTAATTGAACATATTATTGAATTTACAGATGTTGATTCAATTGTAATCACAGGCGGAACAGGTCTT
TCTAAAAGAGATATTACAGCTGATGTTGTAAAAAGTATGTATGAAAAAGAACTTGACGGTTTTAAAATAATATTCCATAA
TTTAAGCTATGGTGAAGTAAAATACTCAACAATCCTTTCAAGAGCATCTGCGGGACTTTACAAAGGAAAAATCATATATT
CACTTCCAGGATCCATTAATGCATGTAAAACCGCACTTGACATTATTAAAACAGAAACCGGCCATATTATCGGCCATATA
AAATAA

Upstream 100 bases:

>100_bases
TAGAACTTTTGGACAAAGAAGACAAACTGGGAATAAAAATGGGTTATACTATTGGAGAAGCAAGAAATAATATTAAAGAG
TTTATAAAGGGGGAATAAGC

Downstream 100 bases:

>100_bases
AAAAAAGTTATAAAAACTATTTTTTAATATTTATGAACATGGATATCCATCTGTGGGAATGGAATTTCAATACCTTCTTT
TCCGTATTTTTCGTAGATTC

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MHERISDVRYAVITVSDSRFNEIISGHDITDKSGEFLKDELGAKIYHLIPDSKTMLEGLIEHIIEFTDVDSIVITGGTGL
SKRDITADVVKSMYEKELDGFKIIFHNLSYGEVKYSTILSRASAGLYKGKIIYSLPGSINACKTALDIIKTETGHIIGHI
K

Sequences:

>Translated_161_residues
MHERISDVRYAVITVSDSRFNEIISGHDITDKSGEFLKDELGAKIYHLIPDSKTMLEGLIEHIIEFTDVDSIVITGGTGL
SKRDITADVVKSMYEKELDGFKIIFHNLSYGEVKYSTILSRASAGLYKGKIIYSLPGSINACKTALDIIKTETGHIIGHI
K
>Mature_161_residues
MHERISDVRYAVITVSDSRFNEIISGHDITDKSGEFLKDELGAKIYHLIPDSKTMLEGLIEHIIEFTDVDSIVITGGTGL
SKRDITADVVKSMYEKELDGFKIIFHNLSYGEVKYSTILSRASAGLYKGKIIYSLPGSINACKTALDIIKTETGHIIGHI
K

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Escherichia coli, GI1787000, Length=146, Percent_Identity=32.1917808219178, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1786190, Length=113, Percent_Identity=29.2035398230088, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564954, Length=164, Percent_Identity=29.8780487804878, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136978, Length=159, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24638841, Length=159, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17848; Mature: 17848

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHERISDVRYAVITVSDSRFNEIISGHDITDKSGEFLKDELGAKIYHLIPDSKTMLEGLI
CCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHHHH
EHIIEFTDVDSIVITGGTGLSKRDITADVVKSMYEKELDGFKIIFHNLSYGEVKYSTILS
HHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
RASAGLYKGKIIYSLPGSINACKTALDIIKTETGHIIGHIK
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MHERISDVRYAVITVSDSRFNEIISGHDITDKSGEFLKDELGAKIYHLIPDSKTMLEGLI
CCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHHHH
EHIIEFTDVDSIVITGGTGLSKRDITADVVKSMYEKELDGFKIIFHNLSYGEVKYSTILS
HHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
RASAGLYKGKIIYSLPGSINACKTALDIIKTETGHIIGHIK
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]