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The map label for this gene is bioI [H]

Identifier: 37521511

GI number: 37521511

Start: 2067770

End: 2069041

Strand: Reverse

Name: bioI [H]

Synonym: gll1942

Alternate gene names: 37521511

Gene position: 2069041-2067770 (Counterclockwise)

Preceding gene: 37521512

Following gene: 37521510

Centisome position: 44.41

GC content: 59.04

Gene sequence:

>1272_bases
ATGGATTCTGTCGCCAATCTCAATCAGGATGCGTTCGGCAATACGCTGCCCCAAACAGAAGCACCCTTTAAATTCAATGT
TTTCGATCCCGCTTTTCACGAAGATCCCTATCCGTTTTACGACCGTCTGCGCCGCGAGTCTCCCATCTATCGCAACTTTA
TGGGTGCCTGGGTATTTACCCGCTACAGCGATATCAAATCCATCCTGCGCGACCGGCGCTTTCGCGTCCTCGACAAGCCC
GGCTGGATCAAAAACAAAAATCGCTATCTCACACCGGATCAGGGAAACTTCGATGCCCTGGTCCGCTCCAGCAGCAAGTT
TTTCTTCTTCCTGGAACCTCCCGATCACGGCCGGTTGCGGGGACTGATCACCAAGGCTTTTAGCGCAAGTTTTGTCGATC
GGCTGCGTCCGCACGTCGAGGCGACCCTGGCGGATTTGCTGGGTAAGGTGCGCGAGCAAGGTGCGATGGACATCATGGCC
GACTTGGCCTGCCCGCTTCCGGCCATCGTCATTGCCCGGCTCATCGGAGTGCCGGCGGCGGATTATGCCCGGTTGGGGCA
CCTGTCGGACGAACTGGCGCGCATCTTCGACCCGGTGATTTCCCTGGAAGGCTATCTGCACTTAAATGCGGTGGTCGAGG
AATTCGGCAGTTATTTTCTTGATCTTGTCGCCGAGCACAAGCGACAGCCGGGCACGGATCTCATCGACAGTTTGATCGCC
GCCCAGGAGGAAGGCAACCGCCTCAGTGAGGAGGAAGTGGTCGCCGTCTGTATGCAGCTGTTTGCCGGGGGTGAAGAGAC
GACGGTCAATCTCATCGGCAACGGCATGCTCGCCCTGCTGACCCATCCGGAGCAACTGGAACTCCTGCGCAGTAAGCCGG
AGATCATCGCCGGCGCGGTCGAGGAGTTGCTGCGCTACGACAGTTCGATTCAACTGGTCGCCCGGGCGGCAATCGAGGAT
ATCGAGATAGAAGGTTGCACGATTGGCGCCGGTGAGCACGTACATCTGTACCTGGGGGCAGCCAACCGCGACCCGGCCCA
GTTTTTCGATCCCCACAGCTTGGATCTCACCCGCGTCGACAACCGCCATCTCGCTTTCGGCGACGGCATTCACCATTGCT
TCGGCGGTCCGCTGGCGCGTGTGGAAGGTCAGGTCGTCTTTCAAACCCTGGTGCAGCAATTCCCGAAGCTGCGCCTCGCG
GAGAGTCGGCGGCCCGAGCGGCGCGAAGGGACGCTCTTGCGTGGGTTGAAGACGTTGCCTGTCACCTTTTGA

Upstream 100 bases:

>100_bases
TTTTGGGAATTTATCAACATCGAATCGGTCGCCGAACACCTCGGCGCCTGATCAATGCTTGAAAAACCAGTTGCCCCGGC
TCACCATCGAGGAGCAGACC

Downstream 100 bases:

>100_bases
TGGCTGCGGGAGCAAACGGTATGGATAGAGAACCAATCGCCATCGTCGGGATGGGCTGCCGGTTTCCCGGCGGGGTCGAC
AGCCCCGGCCAATTCTGGCA

Product: cytochrome P-450 like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MDSVANLNQDAFGNTLPQTEAPFKFNVFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFTRYSDIKSILRDRRFRVLDKP
GWIKNKNRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLRGLITKAFSASFVDRLRPHVEATLADLLGKVREQGAMDIMA
DLACPLPAIVIARLIGVPAADYARLGHLSDELARIFDPVISLEGYLHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIA
AQEEGNRLSEEEVVAVCMQLFAGGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAVEELLRYDSSIQLVARAAIED
IEIEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVDNRHLAFGDGIHHCFGGPLARVEGQVVFQTLVQQFPKLRLA
ESRRPERREGTLLRGLKTLPVTF

Sequences:

>Translated_423_residues
MDSVANLNQDAFGNTLPQTEAPFKFNVFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFTRYSDIKSILRDRRFRVLDKP
GWIKNKNRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLRGLITKAFSASFVDRLRPHVEATLADLLGKVREQGAMDIMA
DLACPLPAIVIARLIGVPAADYARLGHLSDELARIFDPVISLEGYLHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIA
AQEEGNRLSEEEVVAVCMQLFAGGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAVEELLRYDSSIQLVARAAIED
IEIEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVDNRHLAFGDGIHHCFGGPLARVEGQVVFQTLVQQFPKLRLA
ESRRPERREGTLLRGLKTLPVTF
>Mature_423_residues
MDSVANLNQDAFGNTLPQTEAPFKFNVFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFTRYSDIKSILRDRRFRVLDKP
GWIKNKNRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLRGLITKAFSASFVDRLRPHVEATLADLLGKVREQGAMDIMA
DLACPLPAIVIARLIGVPAADYARLGHLSDELARIFDPVISLEGYLHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIA
AQEEGNRLSEEEVVAVCMQLFAGGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAVEELLRYDSSIQLVARAAIED
IEIEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVDNRHLAFGDGIHHCFGGPLARVEGQVVFQTLVQQFPKLRLA
ESRRPERREGTLLRGLKTLPVTF

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 47510; Mature: 47510

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVANLNQDAFGNTLPQTEAPFKFNVFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFT
CCCCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
RYSDIKSILRDRRFRVLDKPGWIKNKNRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLR
HHHHHHHHHHHCHHEECCCCCCCCCCCCEECCCCCCHHHHHCCCCCEEEEECCCCCCHHH
GLITKAFSASFVDRLRPHVEATLADLLGKVREQGAMDIMADLACPLPAIVIARLIGVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCH
DYARLGHLSDELARIFDPVISLEGYLHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AQEEGNRLSEEEVVAVCMQLFAGGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAV
HHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHCCHHHHHHHH
EELLRYDSSIQLVARAAIEDIEIEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVD
HHHHHCCCHHHHHHHHHHHHCEECCEEECCCCEEEEEEECCCCCCHHHCCCCCCEEEECC
NRHLAFGDGIHHCFGGPLARVEGQVVFQTLVQQFPKLRLAESRRPERREGTLLRGLKTLP
CCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHCCHHHHHHHHCC
VTF
CCC
>Mature Secondary Structure
MDSVANLNQDAFGNTLPQTEAPFKFNVFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFT
CCCCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
RYSDIKSILRDRRFRVLDKPGWIKNKNRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLR
HHHHHHHHHHHCHHEECCCCCCCCCCCCEECCCCCCHHHHHCCCCCEEEEECCCCCCHHH
GLITKAFSASFVDRLRPHVEATLADLLGKVREQGAMDIMADLACPLPAIVIARLIGVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCH
DYARLGHLSDELARIFDPVISLEGYLHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AQEEGNRLSEEEVVAVCMQLFAGGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAV
HHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHCCHHHHHHHH
EELLRYDSSIQLVARAAIEDIEIEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVD
HHHHHCCCHHHHHHHHHHHHCEECCEEECCCCEEEEEEECCCCCCHHHCCCCCCEEEECC
NRHLAFGDGIHHCFGGPLARVEGQVVFQTLVQQFPKLRLAESRRPERREGTLLRGLKTLP
CCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHCCHHHHHHHHCC
VTF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]